4WK6

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG) (G141A) from Vibrio cholerae in complex with NADPH

Summary for 4WK6

• Entry DOI: 10.2210/pdb4wk6/pdb
• Related: 3OP4 3RRO 3RSH 3TZC 3TZH 3TZK 3U09 4I08 4WJZ
• Descriptor: 3-oxoacyl-[acyl-carrier protein] reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, PENTAETHYLENE GLYCOL, ... (4 entities in total)
• Functional Keywords: structural genomics, center for structural genomics of infectious diseases, csgid, oxidoreductase, fabg, acyl carrier protein, cell plasma
• Biological source: Vibrio cholerae 12129(1)
• Total number of polymer chains: 4
• Total formula weight: 108708.53

Authors

Hou, J.,Zheng, H.,Anderson, W.F.,Minor, W.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-10-01, release date: 2014-11-12, Last modification date: 2023-12-27)

• Primary citation: Hou, J.,Zheng, H.,Chruszcz, M.,Zimmerman, M.D.,Shumilin, I.A.,Osinski, T.,Demas, M.,Grimshaw, S.,Minor, W.; Dissecting the Structural Elements for the Activation of beta-Ketoacyl-(Acyl Carrier Protein) Reductase from Vibrio cholerae.; J.Bacteriol., 198:463-476, 2015; PubMed: 26553852; DOI: 10.1128/JB.00360-15

Experimental method

X-RAY DIFFRACTION (2.21 Å)