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2ONK
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ABC TRANSPORTER MODBC IN COMPLEX WITH ITS BINDING PROTEIN MODA
Descriptor:Molybdate/tungstate ABC transporter, ATP-binding protein, permease protein, ...
Authors:Hollenstein, K., Frei, D.C., Locher, K.P.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of an ABC transporter in complex with its binding protein.
Nature, 446, 2007
2ONR
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CRYSTAL STRUCTURE OF A. FULGIDUS PERIPLASMIC BINDING PROTEIN MODA WITH BOUND MOLYBDATE
Descriptor:UPF0100 protein AF_0094, NITRATE ION, MAGNESIUM ION, ...
Authors:Hollenstein, K., Frei, D.C., Locher, K.P.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structure of an ABC transporter in complex with its binding protein.
Nature, 446, 2007
2ONS
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CRYSTAL STRUCTURE OF A. FULGIDUS PERIPLASMIC BINDING PROTEIN MODA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein AF_0094, TUNGSTATE(VI)ION, MAGNESIUM ION, ...
Authors:Hollenstein, K., Frei, D.C., Locher, K.P.
Deposit date:2007-01-24
Release date:2007-03-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structure of an ABC transporter in complex with its binding protein.
Nature, 446, 2007
4K5Y
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CRYSTAL STRUCTURE OF HUMAN CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRF1R) IN COMPLEX WITH THE ANTAGONIST CP-376395
Descriptor:Corticotropin-releasing factor receptor 1, T4-Lysozyme chimeric construct, 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, ...
Authors:Hollenstein, K., Kean, J., Bortolato, A., Cheng, R.K.Y., Dore, A.S., Jazayeri, A., Cooke, R.M., Weir, M., Marshall, F.H.
Deposit date:2013-04-15
Release date:2013-07-17
Last modified:2017-08-09
Method:X-RAY DIFFRACTION (2.977 Å)
Cite:Structure of class B GPCR corticotropin-releasing factor receptor 1.
Nature, 499, 2013
3CFX
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CRYSTAL STRUCTURE OF M. ACETIVORANS PERIPLASMIC BINDING PROTEIN MODA/WTPA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein MA_0280, MAGNESIUM ION, TUNGSTATE(VI)ION, ...
Authors:Comellas-Bigler, M., Hollenstein, K., Locher, K.P.
Deposit date:2008-03-04
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
J.Biol.Inorg.Chem., 14, 2009
3CFZ
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CRYSTAL STRUCTURE OF M. JANNASCHII PERIPLASMIC BINDING PROTEIN MODA/WTPA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein MJ1186, TUNGSTATE(VI)ION
Authors:Comellas-Bigler, M., Hollenstein, K., Locher, K.P.
Deposit date:2008-03-04
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
J.Biol.Inorg.Chem., 14, 2009
3CG1
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CRYSTAL STRUCTURE OF P. FURIOSUS PERIPLASMIC BINDING PROTEIN MODA/WTPA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein PF0080, TUNGSTATE(VI)ION
Authors:Comellas-Bigler, M., Hollenstein, K., Locher, K.P.
Deposit date:2008-03-04
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
J.Biol.Inorg.Chem., 14, 2009
3CG3
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CRYSTAL STRUCTURE OF P. HORIKOSHII PERIPLASMIC BINDING PROTEIN MODA/WTPA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein PH0151, TUNGSTATE(VI)ION
Authors:Comellas-Bigler, M., Hollenstein, K., Locher, K.P.
Deposit date:2008-03-04
Release date:2009-03-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
J.Biol.Inorg.Chem., 14, 2009
3CIJ
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CRYSTAL STRUCTURE OF A. FULGIDUS PERIPLASMIC BINDING PROTEIN MODA/WTPA WITH BOUND TUNGSTATE
Descriptor:UPF0100 protein AF_0094, TUNGSTATE(VI)ION, SULFATE ION
Authors:Comellas-Bigler, M., Hollenstein, K., Locher, K.P.
Deposit date:2008-03-11
Release date:2009-03-10
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Distorted octahedral coordination of tungstate in a subfamily of specific binding proteins.
J.Biol.Inorg.Chem., 14, 2009
3REY
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THERMOSTABILISED ADENOSINE A2A RECEPTOR IN COMPLEX WITH XAC
Descriptor:Adenosine receptor A2a, N-(2-aminoethyl)-2-[4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)phenoxy]acetamide
Authors:Dore, A.S., Robertson, N., Errey, J.C., Ng, I., Hollenstein, K., Tehan, B., Hurrell, E., Bennett, K., Congreve, M., Magnani, F., Tate, C.G., Weir, M., Marshall, F.H.
Deposit date:2011-04-05
Release date:2011-09-07
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.309 Å)
Cite:Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
Structure, 19, 2011
3RFM
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THERMOSTABILISED ADENOSINE A2A RECEPTOR IN COMPLEX WITH CAFFEINE
Descriptor:Adenosine receptor A2a, CAFFEINE
Authors:Dore, A.S., Robertson, N., Errey, J.C., Ng, I., Hollenstein, K., Tehan, B., Hurrell, E., Bennett, K., Congreve, M., Magnani, F., Tate, C.G., Weir, M., Marshall, F.H.
Deposit date:2011-04-06
Release date:2011-09-07
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.598 Å)
Cite:Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
Structure, 19, 2011
5UNF
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XFEL STRUCTURE OF HUMAN ANGIOTENSIN II TYPE 2 RECEPTOR (MONOCLINIC FORM) IN COMPLEX WITH COMPOUND 1 (N-BENZYL-N-(2-ETHYL-4-OXO-3-{[2'-(2H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL])
Descriptor:Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide
Authors:Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
Deposit date:2017-01-30
Release date:2017-04-05
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
5UNG
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XFEL STRUCTURE OF HUMAN ANGIOTENSIN II TYPE 2 RECEPTOR (ORTHORHOMBIC FORM) IN COMPLEX WITH COMPOUND 1 (N-BENZYL-N-(2-ETHYL-4-OXO-3-{[2'-(2H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL] METHYL}-3,4-DIHYDROQUINAZOLIN-6-YL)THIOPHENE-2-CARBOXAMIDE)
Descriptor:Chimera protein of Type-2 angiotensin II receptor and Soluble cytochrome b562, N-benzyl-N-(2-ethyl-4-oxo-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)thiophene-2-carboxamide, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ...
Authors:Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
Deposit date:2017-01-30
Release date:2017-04-05
Last modified:2018-11-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
5UNH
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SYNCHROTRON STRUCTURE OF HUMAN ANGIOTENSIN II TYPE 2 RECEPTOR IN COMPLEX WITH COMPOUND 2 (N-[(FURAN-2-YL)METHYL]-N-(4-OXO-2-PROPYL-3-{[2'-(2H-TETRAZOL-5-YL)[1,1'- BIPHENYL]-4-YL]METHYL}-3,4-DIHYDROQUINAZOLIN-6-YL)BENZAMIDE)
Descriptor:Soluble cytochrome b562,Type-2 angiotensin II receptor, N-[(furan-2-yl)methyl]-N-(4-oxo-2-propyl-3-{[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-3,4-dihydroquinazolin-6-yl)benzamide
Authors:Zhang, H., Han, G.W., Batyuk, A., Ishchenko, A., White, K.L., Patel, N., Sadybekov, A., Zamlynny, B., Rudd, M.T., Hollenstein, K., Tolstikova, A., White, T.A., Hunter, M.S., Weierstall, U., Liu, W., Babaoglu, K., Moore, E.L., Katz, R.D., Shipman, J.M., Garcia-Calvo, M., Sharma, S., Sheth, P., Soisson, S.M., Stevens, R.C., Katritch, V., Cherezov, V.
Deposit date:2017-01-30
Release date:2017-04-05
Last modified:2017-05-10
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis for selectivity and diversity in angiotensin II receptors.
Nature, 544, 2017
2QI9
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ABC-TRANSPORTER BTUCD IN COMPLEX WITH ITS PERIPLASMIC BINDING PROTEIN BTUF
Descriptor:Vitamin B12 import system permease protein btuC, Vitamin B12 import ATP-binding protein btuD, Vitamin B12-binding protein btuF, ...
Authors:Hvorup, R.N., Goetz, B.A., Niederer, M., Hollenstein, K., Perozo, E., Locher, K.P.
Deposit date:2007-07-03
Release date:2007-08-14
Last modified:2017-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Asymmetry in the structure of the ABC transporter-binding protein complex BtuCD-BtuF.
Science, 317, 2007
3UZA
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THERMOSTABILISED ADENOSINE A2A RECEPTOR IN COMPLEX WITH 6-(2,6-DIMETHYLPYRIDIN-4-YL)-5-PHENYL-1,2,4-TRIAZIN-3-AMINE
Descriptor:Adenosine receptor A2a, 6-(2,6-dimethylpyridin-4-yl)-5-phenyl-1,2,4-triazin-3-amine
Authors:Congreve, M., Andrews, S.P., Dore, A.S., Hollenstein, K., Hurrell, E., Langmead, C.J., Mason, J.S., Ng, I.W., Tehan, B., Zhukov, A., Weir, M., Marshall, F.H.
Deposit date:2011-12-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (3.273 Å)
Cite:Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design
J.Med.Chem., 55, 2012
3UZC
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THERMOSTABILISED ADENOSINE A2A RECEPTOR IN COMPLEX WITH 4-(3-AMINO-5-PHENYL-1,2,4-TRIAZIN-6-YL)-2-CHLOROPHENOL
Descriptor:Adenosine A2A Receptor, 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol
Authors:Congreve, M., Andrews, S.P., Dore, A.S., Hollenstein, K., Hurrell, E., Langmead, C.J., Mason, J.S., Ng, I.W., Zhukov, A., Weir, M., Marshall, F.H.
Deposit date:2011-12-07
Release date:2012-03-21
Method:X-RAY DIFFRACTION (3.341 Å)
Cite:Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design
J.Med.Chem., 55, 2012
4Z9G
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CRYSTAL STRUCTURE OF HUMAN CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRF1R) IN COMPLEX WITH THE ANTAGONIST CP-376395 IN A HEXAGONAL SETTING WITH TRANSLATIONAL NON-CRYSTALLOGRAPHIC SYMMETRY
Descriptor:Corticotropin-releasing factor receptor 1,Lysozyme,Corticotropin-releasing factor receptor 1, OLEIC ACID, 3,6-dimethyl-N-(pentan-3-yl)-2-(2,4,6-trimethylphenoxy)pyridin-4-amine, ...
Authors:Dore, A.S., Bortolato, A., Hollenstein, K., Cheng, R.K.Y., Read, R.J., Marshall, F.H.
Deposit date:2015-04-10
Release date:2016-06-29
Last modified:2017-12-06
Method:X-RAY DIFFRACTION (3.183 Å)
Cite:Decoding Corticotropin-Releasing Factor Receptor Type 1 Crystal Structures.
Curr Mol Pharmacol, 10, 2017
3PWH
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THERMOSTABILISED ADENOSINE A2A RECEPTOR
Descriptor:Adenosine receptor A2a, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol
Authors:Dore, A.S., Robertson, N., Errey, J.C., Ng, I., Tehan, B., Hurrell, E., Magnani, F., Tate, C.G., Weir, M., Marshall, F.H.
Deposit date:2010-12-08
Release date:2011-09-07
Last modified:2012-06-20
Method:X-RAY DIFFRACTION (3.296 Å)
Cite:Structure of the adenosine A(2A) receptor in complex with ZM241385 and the xanthines XAC and caffeine
Structure, 19, 2011