Summary for 3UZC
| Related | 3UZA 3PWH 3RFM 3REY |
|---|---|
| Descriptor | Adenosine A2A Receptor, 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol (2 entities in total) |
| Functional Keywords | 7tm, gpcr, g-protein, membrane protein, signaling protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cell membrane; Multi-pass membrane protein P29274 |
| Total number of polymer chains | 1 |
| Total molecular weight | 36777.83 |
| Authors | Congreve, M.,Andrews, S.P.,Dore, A.S.,Hollenstein, K.,Hurrell, E.,Langmead, C.J.,Mason, J.S.,Ng, I.W.,Zhukov, A.,Weir, M.,Marshall, F.H. (deposition date: 2011-12-07, release date: 2012-03-21) |
| Primary citation | Congreve, M.,Andrews, S.P.,Dore, A.S.,Hollenstein, K.,Hurrell, E.,Langmead, C.J.,Mason, J.S.,Ng, I.W.,Tehan, B.,Zhukov, A.,Weir, M.,Marshall, F.H. Discovery of 1,2,4-Triazine Derivatives as Adenosine A(2A) Antagonists using Structure Based Drug Design J.Med.Chem., 55:1898-1903, 2012 PubMed: 22220592 (PDB entries with the same primary citation) DOI: 10.1021/jm201376w  Import into Mendeley |
| Experimental method | X-RAY DIFFRACTION (3.341 Å) |
