3UZC

Thermostabilised Adenosine A2A receptor in complex with 4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Adenosine A2A Receptor	polymer	329	36479.1	1	UniProt (P29274) Pfam (PF00001)	Homo sapiens (human)
2	B (A)	4-(3-amino-5-phenyl-1,2,4-triazin-6-yl)-2-chlorophenol	non-polymer		298.7	1	Chemie (T4E)

Sequence modifications

A: 1 - 317 (UniProt: P29274)

PDB	External Database	Details
Leu 54	Ala 54	engineered mutation
Ala 88	Thr 88	engineered mutation
Ala 107	Arg 107	engineered mutation
Ala 122	Lys 122	engineered mutation
Ala 202	Leu 202	engineered mutation
Ala 235	Leu 235	engineered mutation
Ala 239	Val 239	engineered mutation
Ala 277	Ser 277	engineered mutation
Ala 318	-	expression tag
Ala 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag
His 327	-	expression tag
His 328	-	expression tag
His 329	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	36479.1
Non-Polymers*	Number of molecules	1
	Total formula weight	298.7
All*	Total formula weight	36777.8

*Water molecules are not included.