Author results

3CD4
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REFINEMENT AND ANALYSIS OF THE FIRST TWO DOMAINS OF HUMAN CD4
Descriptor:T CELL SURFACE GLYCOPROTEIN CD4
Authors:Garrett, T.P.J., Wang, J., Yan, Y., Harrison, S.C.
Deposit date:1992-07-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Refinement and analysis of the structure of the first two domains of human CD4
J.Mol.Biol., 234, 1993
1MOX
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CRYSTAL STRUCTURE OF HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR (RESIDUES 1-501) IN COMPLEX WITH TGF-ALPHA
Descriptor:Epidermal Growth Factor Receptor, Transforming Growth Factor alpha, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Garrett, T.P.J., McKern, N.M., Lou, M., Elleman, T.C., Adams, T.E., Lovrecz, G.O., Zhu, H.-J., Walker, F., Frenkel, M.J., Hoyne, P.A., Jorissen, R.N., Nice, E.C., Burgess, A.W., Ward, C.W.
Deposit date:2002-09-10
Release date:2003-09-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal Structure of a Truncated Epidermal Growth Factor Receptor Extracellular Domain Bound to Transforming Growth Factor alpha
Cell(Cambridge,Mass.), 110, 2002
2A91
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CRYSTAL STRUCTURE OF ERBB2 DOMAINS 1-3
Descriptor:Receptor tyrosine-protein kinase erbB-2, N-ACETYL-D-GLUCOSAMINE
Authors:Garrett, T.P.J., McKern, N.M., Lou, M., Elleman, T.C., Adams, T.E., Lovrecz, G.O., Kofler, M., Jorissen, R.N., Nice, E.C., Burgess, A.W.
Deposit date:2005-07-11
Release date:2005-07-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Crystal Structure of a Truncated ErbB2 Ectodomain Reveals an Active Conformation, Poised to Interact with Other ErbB Receptors
Mol.Cell, 11, 2003
3G5V
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ANTIBODIES SPECIFICALLY TARGETING A LOCALLY MISFOLDED REGION OF TUMOR ASSOCIATED EGFR
Descriptor:806 light chain, 808 heavy chain, Epidermal Growth Factor Receptor peptide, ...
Authors:Garrett, T.P.J., Burgess, A.W., Huyton, T., Xu, Y.
Deposit date:2009-02-05
Release date:2010-02-09
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.001 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5X
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ANTIBODIES SPECIFICALLY TARGETING A LOCALLY MISFOLDED REGION OF TUMOR ASSOCIATED EGFR
Descriptor:806 light chain, 806 heavy chain
Authors:Garrett, T.P.J., Burgess, A.W.
Deposit date:2009-02-05
Release date:2009-12-15
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5Y
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ANTIBODIES SPECIFICALLY TARGETING A LOCALLY MISFOLDED REGION OF TUMOR ASSOCIATED EGFR
Descriptor:175 light chain, 175 heavy chain, EGFR peptide
Authors:Garrett, T.P.J., Burgess, A.W.
Deposit date:2009-02-05
Release date:2010-02-09
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
3G5Z
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ANTIBODIES SPECIFICALLY TARGETING A LOCALLY MISFOLDED REGION OF TUMOR ASSOCIATED EGFR
Descriptor:175 light chain, 175 heavy chain
Authors:Garrett, T.P.J., Burgess, A.W.
Deposit date:2009-02-05
Release date:2010-02-09
Last modified:2011-10-12
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Antibodies specifically targeting a locally misfolded region of tumor associated EGFR
Proc.Natl.Acad.Sci.USA, 106, 2009
1GHS
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THE THREE-DIMENSIONAL STRUCTURES OF TWO PLANT BETA-GLUCAN ENDOHYDROLASES WITH DISTINCT SUBSTRATE SPECIFICITIES
Descriptor:1,3-BETA-GLUCANASE
Authors:Garrett, T.P.J., Varghese, J.N.
Deposit date:1993-10-12
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities.
Proc.Natl.Acad.Sci.USA, 91, 1994
1IGR
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TYPE 1 INSULIN-LIKE GROWTH FACTOR RECEPTOR (DOMAINS 1-3)
Descriptor:INSULIN-LIKE GROWTH FACTOR RECEPTOR 1, N-ACETYL-D-GLUCOSAMINE, ALPHA-L-FUCOSE, ...
Authors:Garrett, T.P.J., Mckern, N.M., Lou, M., Frenkel, M.J., Bentley, J.D., Lovrecz, G.O., Elleman, T.C., Cosgrove, L.J., Ward, C.W.
Deposit date:1998-09-28
Release date:1999-09-27
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the first three domains of the type-1 insulin-like growth factor receptor.
Nature, 394, 1998
2HLA
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SPECIFICITY POCKETS FOR THE SIDE CHAINS OF PEPTIDE ANTIGENS IN HLA-AW68
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-Aw68), BETA 2-MICROGLOBULIN
Authors:Garrett, T.P.J., Saper, M.A., Wiley, D.C.
Deposit date:1989-10-05
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Specificity pockets for the side chains of peptide antigens in HLA-Aw68.
Nature, 342, 1989
1GHR
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THE THREE-DIMENSIONAL STRUCTURES OF TWO PLANT BETA-GLUCAN ENDOHYDROLASES WITH DISTINCT SUBSTRATE SPECIFICITIES
Descriptor:1,3-1,4-BETA-GLUCANASE
Authors:Varghese, J.N., Garrett, T.P.J.
Deposit date:1993-10-11
Release date:1994-11-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Three-dimensional structures of two plant beta-glucan endohydrolases with distinct substrate specificities.
Proc.Natl.Acad.Sci.USA, 91, 1994
2HR7
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INSULIN RECEPTOR (DOMAINS 1-3)
Descriptor:Insulin receptor, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Garrett, T.P.J., Ward, C.W.
Deposit date:2006-07-19
Release date:2006-08-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:The first three domains of the insulin receptor differ structurally from the insulin-like growth factor 1 receptor in the regions governing ligand specificity.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2PCY
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THE CRYSTAL STRUCTURE OF POPLAR APOPLASTOCYANIN AT 1.8-ANGSTROMS RESOLUTION. THE GEOMETRY OF THE COPPER-BINDING SITE IS CREATED BY THE POLYPEPTIDE
Descriptor:PLASTOCYANIN
Authors:Garrett, T.P.J., Guss, J.M., Freeman, H.C.
Deposit date:1983-11-03
Release date:1984-02-02
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of poplar apoplastocyanin at 1.8-A resolution. The geometry of the copper-binding site is created by the polypeptide
J.Biol.Chem., 259, 1984
1HSB
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DIFFERENT LENGTH PEPTIDES BIND TO HLA-AW68 SIMILARLY AT THEIR ENDS BUT BULGE OUT IN THE MIDDLE
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68.1), BETA 2-MICROGLOBULIN, BOUND PEPTIDE FRAGMENT, ...
Authors:Guo, H.-C., Strominger, J.L., Wiley, D.C.
Deposit date:1993-03-30
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle.
Nature, 360, 1992
1MOE
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THE THREE-DIMENSIONAL STRUCTURE OF AN ENGINEERED SCFV T84.66 DIMER OR DIABODY IN VL TO VH LINKAGE.
Descriptor:anti-CEA mAb T84.66, SULFATE ION
Authors:Carmichael, J.A., Power, B.E., Garrett, T.P.J., Yazaki, P.J., Shively, J.E., Raubischek, A.A., Wu, A.M., Hudson, P.J.
Deposit date:2002-09-09
Release date:2003-03-18
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The Crystal Structure of an Anti-CEA scFv Diabody Assembled from T84.66 scFvs in VL-to-VH Orientation: Implications for Diabody Flexibility
J.Mol.Biol., 326, 2003
2B8H
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A/NWS/WHALE/MAINE/1/84 (H1N9) REASSORTANT INFLUENZA VIRUS NEURAMINIDASE
Descriptor:Neuraminidase, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE, ...
Authors:Smith, B.J., Platis, D., Cox, M.M.J., Huyton, T., Joosten, R.P., McKimm-Breschkin, J.L., Zhang, J.-G., Luo, C.S., Lou, M.-Z., Garrett, T.P.J., Labrou, N.E.
Deposit date:2005-10-07
Release date:2006-09-05
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a calcium-deficient form of influenza virus neuraminidase: implications for substrate binding.
Acta Crystallogr.,Sect.D, 62, 2006
2Q7N
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CRYSTAL STRUCTURE OF LEUKEMIA INHIBITORY FACTOR IN COMPLEX WITH LIF RECEPTOR (DOMAINS 1-5)
Descriptor:Leukemia inhibitory factor receptor, Leukemia inhibitory factor, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Huyton, T., Zhang, J.G., Nicola, N.A., Garrett, T.P.J.
Deposit date:2007-06-07
Release date:2007-07-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (4 Å)
Cite:An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor.
Proc.Natl.Acad.Sci.USA, 104, 2007
3L5H
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CRYSTAL STRUCTURE OF THE FULL ECTODOMAIN OF HUMAN GP130: NEW INSIGHTS INTO THE MOLECULAR ASSEMBLY OF RECEPTOR COMPLEXES
Descriptor:Interleukin-6 receptor subunit beta, SULFATE ION, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Xu, Y., Garrett, T.P.J., Zhang, J.G.
Deposit date:2009-12-21
Release date:2010-05-19
Last modified:2017-04-05
Method:X-RAY DIFFRACTION (3.6 Å)
Cite:Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
3L5I
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CRYSTAL STRUCTURE OF FNIII DOMAINS OF HUMAN GP130 (DOMAINS 4-6)
Descriptor:Interleukin-6 receptor subunit beta, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Kershaw, N.J., Zhang, J.-G., Garrett, T.P.J., Czabotar, P.E.
Deposit date:2009-12-22
Release date:2010-05-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
3L5J
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CRYSTAL STRUCTURE OF FNIII DOMAINS OF HUMAN GP130 (DOMAINS 4-6)
Descriptor:Interleukin-6 receptor subunit beta, 1,2-ETHANEDIOL, CHLORIDE ION
Authors:Kershaw, N.J., Zhang, J.-G., Garrett, T.P.J., Czabotar, P.E.
Deposit date:2009-12-22
Release date:2010-05-12
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (3.042 Å)
Cite:Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.
J.Biol.Chem., 285, 2010
1HSA
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THE THREE-DIMENSIONAL STRUCTURE OF HLA-B27 AT 2.1 ANGSTROMS RESOLUTION SUGGESTS A GENERAL MECHANISM FOR TIGHT PEPTIDE BINDING TO MHC
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-B*2705), BETA 2-MICROGLOBULIN, MODEL PEPTIDE SEQUENCE - ARAAAAAAA
Authors:Madden, D.R., Gorga, J.C., Strominger, J.L., Wiley, D.C.
Deposit date:1992-08-11
Release date:1992-10-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC.
Cell(Cambridge,Mass.), 70, 1992
1TMC
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THE THREE-DIMENSIONAL STRUCTURE OF A CLASS I MAJOR HISTOCOMPATIBILITY COMPLEX MOLECULE MISSING THE ALPHA3 DOMAIN OF THE HEAVY CHAIN
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-AW68), BETA 2-MICROGLOBULIN, DECAMERIC PEPTIDE (EVAPPEYHRK)
Authors:Collins, E.J., Garboczi, D.N., Karpusas, M.N., Wiley, D.C.
Deposit date:1994-12-19
Release date:1995-03-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The three-dimensional structure of a class I major histocompatibility complex molecule missing the alpha 3 domain of the heavy chain.
Proc.Natl.Acad.Sci.USA, 92, 1995
3HLA
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HUMAN CLASS I HISTOCOMPATIBILITY ANTIGEN A2.1
Descriptor:CLASS I HISTOCOMPATIBILITY ANTIGEN (HLA-A2.1) (ALPHA CHAIN), BETA 2-MICROGLOBULIN
Authors:Saper, M.A., Bjorkman, P.J., Wiley, D.C.
Deposit date:1989-10-06
Release date:1990-04-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Refined structure of the human histocompatibility antigen HLA-A2 at 2.6 A resolution.
J.Mol.Biol., 219, 1991
3PCY
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THE CRYSTAL STRUCTURE OF MERCURY-SUBSTITUTED POPLAR PLASTOCYANIN AT 1.9-ANGSTROMS RESOLUTION
Descriptor:PLASTOCYANIN, MERCURY (II) ION
Authors:Church, W.B., Guss, J.M., Potter, J.J., Freeman, H.C.
Deposit date:1985-12-10
Release date:1986-01-21
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The crystal structure of mercury-substituted poplar plastocyanin at 1.9-A resolution.
J.Biol.Chem., 261, 1986
4PCY
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CRYSTAL STRUCTURE ANALYSES OF REDUCED (CUI) POPLAR PLASTOCYANIN AT SIX PH VALUES
Descriptor:PLASTOCYANIN, COPPER (II) ION
Authors:Guss, J.M., Freeman, H.C.
Deposit date:1986-09-02
Release date:1987-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure analyses of reduced (CuI) poplar plastocyanin at six pH values.
J.Mol.Biol., 192, 1986
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