4V91
| Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES | Descriptor: | 25S RRNA, 5.8S RRNA, 5S RRNA, ... | Authors: | Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V. | Deposit date: | 2014-03-21 | Release date: | 2014-07-09 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome. Cell(Cambridge,Mass.), 157, 2014
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4V9I
| Crystal structure of thermus thermophilus 70S in complex with tRNAs and mRNA containing a pseudouridine in a stop codon | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S Ribosomal protein S10, ... | Authors: | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | Deposit date: | 2013-04-04 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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4V92
| Kluyveromyces lactis 80S ribosome in complex with CrPV-IRES | Descriptor: | 18S RRNA, ES1, ES10, ... | Authors: | Fernandez, I.S, Bai, X, Scheres, S.H.W, Ramakrishnan, V. | Deposit date: | 2014-03-21 | Release date: | 2014-07-09 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome. Cell(Cambridge,Mass.), 157, 2014
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4V8Z
| Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | Descriptor: | 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... | Authors: | Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. | Deposit date: | 2013-07-20 | Release date: | 2014-07-09 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (6.6 Å) | Cite: | Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
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4V8Y
| Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex | Descriptor: | 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ... | Authors: | Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W. | Deposit date: | 2013-07-20 | Release date: | 2014-07-09 | Last modified: | 2024-06-26 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular architecture of a eukaryotic translational initiation complex. Science, 342, 2013
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3BSQ
| Crystal structure of human kallikrein 7 produced as a secretion protein in E.coli | Descriptor: | Kallikrein-7, SULFATE ION | Authors: | Fernandez, I.S, Standker, L, Magert, H.J, Forssmann, W.G, Gimenez-Gallego, G, Romero, A. | Deposit date: | 2007-12-26 | Release date: | 2008-04-29 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6) J.Mol.Biol., 377, 2008
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3FIM
| Crystal structure of aryl-alcohol-oxidase from Pleurotus eryingii | Descriptor: | Aryl-alcohol oxidase, FLAVIN-ADENINE DINUCLEOTIDE | Authors: | Fernandez, I.S. | Deposit date: | 2008-12-12 | Release date: | 2009-11-03 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase Acta Crystallogr.,Sect.D, 65, 2009
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4JYA
| Crystal structures of pseudouridinilated stop codons with ASLs | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | Deposit date: | 2013-03-29 | Release date: | 2013-06-26 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (3.098 Å) | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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4JV5
| Crystal structures of pseudouridinilated stop codons with ASLs | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein 20, 30S ribosomal protein S10, ... | Authors: | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | Deposit date: | 2013-03-25 | Release date: | 2013-06-26 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (3.162 Å) | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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4K0K
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit complexed with a serine-ASL and mRNA containing a stop codon | Descriptor: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | Deposit date: | 2013-04-04 | Release date: | 2013-06-26 | Last modified: | 2013-08-21 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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3JUT
| Acidic Fibroblast Growth Factor (FGF-1) complexed with gentisic acid | Descriptor: | 2,5-dihydroxybenzoic acid, Heparin-binding growth factor 1 | Authors: | Fernandez, I.S, Gimenez-Gallego, G, Romero, A. | Deposit date: | 2009-09-15 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J.Biol.Chem., 285, 2010
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2YMZ
| Crystal structure of chicken Galectin 2 | Descriptor: | GALECTIN 2, SULFATE ION, beta-D-galactopyranose-(1-4)-beta-D-glucopyranose | Authors: | Fernandez, I.S, Ruiz, F.M, Solis, D, Gabius, H.-J, Romero, A. | Deposit date: | 2012-10-11 | Release date: | 2013-08-28 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Fine-Tuning of Prototype Chicken Galectins: Structure of Cg-2 and Structure-Activity Correlations Acta Crystallogr.,Sect.D, 69, 2013
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7UFI
| VchTnsC AAA+ ATPase with DNA, single heptamer | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*CP*TP*CP*CP*AP*GP*TP*AP*CP*AP*GP*CP*GP*CP*GP*GP*CP*TP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*CP*AP*GP*CP*CP*GP*CP*GP*CP*TP*GP*TP*AP*CP*TP*GP*GP*AP*G)-3'), ... | Authors: | Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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7UFM
| VchTnsC AAA+ with DNA (double heptamer) | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, DNA (36-MER), VchTnsC | Authors: | Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2022-03-22 | Release date: | 2022-06-08 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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3K1X
| Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate | Descriptor: | 2,5-dihydroxybenzenesulfonic acid, Heparin-binding growth factor 1 | Authors: | Romero, A, Fernandez, I.S, Gimenez-Gallego, G. | Deposit date: | 2009-09-29 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. J.Biol.Chem., 285, 2010
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6UZ7
| K.lactis 80S ribosome with p/PE tRNA and eIF5B | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Fernandez, I.S, Huang, B.Y. | Deposit date: | 2019-11-14 | Release date: | 2020-01-15 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Long-range interdomain communications in eIF5B regulate GTP hydrolysis and translation initiation. Proc.Natl.Acad.Sci.USA, 117, 2020
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6W2S
| Structure of the Cricket Paralysis Virus 5-UTR IRES (CrPV 5-UTR-IRES) bound to the small ribosomal subunit in the open state (Class 1) | Descriptor: | 18S rRNA, CrPV 5'-UTR IRES, Eukaryotic translation initiation factor 3 subunit A, ... | Authors: | Neupane, R, Pisareva, V, Rodriguez, C.F, Pisarev, A, Fernandez, I.S. | Deposit date: | 2020-03-08 | Release date: | 2020-04-22 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.47 Å) | Cite: | A complex IRES at the 5'-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife, 9, 2020
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4V9H
| Crystal structure of the ribosome bound to elongation factor G in the guanosine triphosphatase state | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Tourigny, D.S, Fernandez, I.S, Kelley, A.C, Ramakrishnan, V. | Deposit date: | 2013-03-25 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (2.857 Å) | Cite: | Elongation factor G bound to the ribosome in an intermediate state of translocation. Science, 340, 2013
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7RZY
| CryoEM structure of Vibrio cholerae transposon Tn6677 AAA+ ATPase TnsC | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Tn6677 Vibrio cholerae transposon TnsC (VchTnsC) | Authors: | Hoffmann, F.T, Kim, M, Beh, L.Y, Wang, J, Vo, P.L.H, Gelsinger, D.R, Acree, C, Mohabir, J.T, Fernandez, I.S, Sternberg, S.H. | Deposit date: | 2021-08-28 | Release date: | 2022-06-08 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Selective TnsC recruitment enhances the fidelity of RNA-guided transposition. Nature, 609, 2022
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6P5J
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P4H
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | Descriptor: | 18S rRNA, IAPV-IRES, RACK1, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-27 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5I
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2020-02-26 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P4G
| Structure of a mammalian small ribosomal subunit in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | Descriptor: | 18S rRNA, IAPV-IRES, RACK1, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-27 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5N
| Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-25 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5K
| Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | Deposit date: | 2019-05-30 | Release date: | 2019-09-18 | Last modified: | 2020-01-08 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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