3BSQ

Crystal structure of human kallikrein 7 produced as a secretion protein in E.coli

Summary for 3BSQ

Entry DOI	10.2210/pdb3bsq/pdb
Descriptor	Kallikrein-7, SULFATE ION (3 entities in total)
Functional Keywords	serine proteases, kallikreins, ld6, x-ray crystal structure, glycoprotein, hydrolase, secreted, zymogen
Biological source	Homo sapiens (human)
Cellular location	Secreted: P49862
Total number of polymer chains	3
Total formula weight	76193.57
Authors	Fernandez, I.S.,Standker, L.,Magert, H.J.,Forssmann, W.G.,Gimenez-Gallego, G.,Romero, A. (deposition date: 2007-12-26, release date: 2008-04-29, Last modification date: 2023-11-01)
Primary citation	Fernandez, I.S.,Standker, L.,Magert, H.J.,Forssmann, W.G.,Gimenez-Gallego, G.,Romero, A. Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6) J.Mol.Biol., 377:1488-1497, 2008 Cited by PubMed: 18329042 DOI: 10.1016/j.jmb.2008.01.089 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation