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3BSQ
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CRYSTAL STRUCTURE OF HUMAN KALLIKREIN 7 PRODUCED AS A SECRETION PROTEIN IN E.COLI
Descriptor:Kallikrein-7 (E.C.3.4.21.117)
Authors:Fernandez, I.S., Standker, L., Magert, H.J., Forssmann, W.G., Gimenez-Gallego, G., Romero, A.
Deposit date:2007-12-26
Release date:2008-04-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human epidermal kallikrein 7 (hK7) synthesized directly in its native state in E. coli: insights into the atomic basis of its inhibition by LEKTI domain 6 (LD6)
J.Mol.Biol., 377, 2008
3FIM
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CRYSTAL STRUCTURE OF ARYL-ALCOHOL-OXIDASE FROM PLEUROTUS ERYINGII
Descriptor:Aryl-alcohol oxidase (E.C.1.1.3.7)
Authors:Fernandez, I.S.
Deposit date:2008-12-12
Release date:2009-11-03
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Novel structural features in the GMC family of oxidoreductases revealed by the crystal structure of fungal aryl-alcohol oxidase
Acta Crystallogr.,Sect.D, 65, 2009
3JUT
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ACIDIC FIBROBLAST GROWTH FACTOR (FGF-1) COMPLEXED WITH GENTISIC ACID
Descriptor:Heparin-binding growth factor 1
Authors:Fernandez, I.S., Gimenez-Gallego, G., Romero, A.
Deposit date:2009-09-15
Release date:2010-02-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
J.Biol.Chem., 285, 2010
4JV5
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CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS
Descriptor:PROTEIN/RNA Complex
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-03-25
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.162 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4JYA
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CRYSTAL STRUCTURES OF PSEUDOURIDINILATED STOP CODONS WITH ASLS
Descriptor:PROTEIN/RNA Complex
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-03-29
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.098 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4K0K
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CRYSTAL STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A SERINE-ASL AND MRNA CONTAINING A STOP CODON
Descriptor:PROTEIN/RNA Complex
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2013-06-26
Last modified:2013-08-21
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
4V8Y
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:80S Ribosome
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Molecular Architecture of a Eukaryotic Translational Initiation Complex.
Science, 342, 2013
4V8Z
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CRYO-EM RECONSTRUCTION OF THE 80S-EIF5B-MET-ITRNAMET EUKARYOTIC TRANSLATION INITIATION COMPLEX
Descriptor:80S Ribosome
Authors:Fernandez, I.S., Bai, X.C., Hussain, T., Kelley, A.C., Lorsch, J.R., Ramakrishnan, V., Scheres, S.H.W.
Deposit date:2013-07-20
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Molecular Architecture of a Eukaryotic Translational Initiation Complex.
Science, 342, 2013
4V91
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:Ribosome
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V92
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:Ribosome
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V9I
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CRYSTAL STRUCTURE OF THERMUS THERMOPHILUS 70S IN COMPLEX WITH TRNAS AND MRNA CONTAINING A PSEUDOURIDINE IN A STOP CODON
Descriptor:PROTEIN/RNA Complex
Authors:Fernandez, I.S., Ng, C.L., Kelley, A.C., Guowei, W., Yu, Y.T., Ramakrishnan, V.
Deposit date:2013-04-04
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature, 500, 2013
2YMZ
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CRYSTAL STRUCTURE OF CHICKEN GALECTIN 2
Descriptor:GALECTIN 2
Authors:Fernandez, I.S., Ruiz, F.M., Solis, D., Gabius, H.-J., Romero, A.
Deposit date:2012-10-11
Release date:2013-08-28
Last modified:2013-09-11
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Fine-Tuning of Prototype Chicken Galectins: Structure of Cg-2 and Structure-Activity Correlations
Acta Crystallogr.,Sect.D, 69, 2013
3K1X
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ACIDIC FIBROBLAST GROWTH FACTOR (FGF-1) COMPLEXED WITH DOBESILATE
Descriptor:Heparin-binding growth factor 1
Authors:Romero, A., Fernandez, I.S., Gimenez-Gallego, G.
Deposit date:2009-09-29
Release date:2010-02-02
Last modified:2010-05-12
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
J.Biol.Chem., 285, 2010
3J79
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, LARGE SUBUNIT
Descriptor:PROTEIN/RNA Complex
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-02
Release date:2014-07-16
Last modified:2015-06-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7A
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CRYO-EM STRUCTURE OF THE PLASMODIUM FALCIPARUM 80S RIBOSOME BOUND TO THE ANTI-PROTOZOAN DRUG EMETINE, SMALL SUBUNIT
Descriptor:PROTEIN/RNA Complex
Authors:Wong, W., Bai, X.C., Brown, A., Fernandez, I.S., Hanssen, E., Condron, M., Tan, Y.H., Baum, J., Scheres, S.H.W.
Deposit date:2014-06-03
Release date:2014-07-16
Last modified:2015-06-03
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine.
Elife, 3, 2014
3J7O
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STRUCTURE OF THE MAMMALIAN 60S RIBOSOMAL SUBUNIT
Descriptor:PROTEIN/RNA Complex
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2014-12-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7P
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STRUCTURE OF THE 80S MAMMALIAN RIBOSOME BOUND TO EEF2
Descriptor:PROTEIN/RNA Complex
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2015-04-15
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7Q
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STRUCTURE OF THE IDLE MAMMALIAN RIBOSOME-SEC61 COMPLEX
Descriptor:PROTEIN/RNA Complex
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2014-12-17
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J7R
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STRUCTURE OF THE TRANSLATING MAMMALIAN RIBOSOME-SEC61 COMPLEX
Descriptor:PROTEIN/RNA Complex
Authors:Voorhees, R.M., Fernandez, I.S., Scheres, S.H.W., Hegde, R.S.
Deposit date:2014-08-01
Release date:2014-09-03
Last modified:2015-04-15
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
3J80
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CRYOEM STRUCTURE OF 40S-EIF1-EIF1A PREINITIATION COMPLEX
Descriptor:PROTEIN/RNA Complex
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-28
Release date:2014-11-05
Last modified:2014-12-24
Method:ELECTRON MICROSCOPY (3.75 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
3J81
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CRYOEM STRUCTURE OF A PARTIAL YEAST 48S PREINITIATION COMPLEX
Descriptor:PROTEIN/RNA Complex
Authors:Hussain, T., Llacer, J.L., Fernandez, I.S., Savva, C.G., Ramakrishnan, V.
Deposit date:2014-08-29
Release date:2014-11-05
Last modified:2014-12-24
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
4KHP
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STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH DE-6-MSA-PACTAMYCIN
Descriptor:PROTEIN/RNA Complex
Authors:Tourigny, D.S., Fernandez, I.S., Kelley, A.C., Ramakrishnan, V.
Deposit date:2013-05-01
Release date:2013-06-05
Last modified:2013-10-30
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal Structure of a Bioactive Pactamycin Analog Bound to the 30S Ribosomal Subunit.
J.Mol.Biol., 425, 2013
4LD9
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CRYSTAL STRUCTURE OF THE N-TERMINALLY ACETYLATED BAH DOMAIN OF SIR3 BOUND TO THE NUCLEOSOME CORE PARTICLE
Descriptor:Histone H3.2, Histone H4, Histone H2A, Histone H2B 1.1, Regulatory protein SIR3
Authors:Arnaudo, N., Fernandez, I.S., McLaughlin, S.H., Peak-Chew, S.Y., Rhodes, D., Martino, F.
Deposit date:2013-06-24
Release date:2013-08-14
Last modified:2013-09-18
Method:X-RAY DIFFRACTION (3.306 Å)
Cite:The N-terminal acetylation of Sir3 stabilizes its binding to the nucleosome core particle.
Nat.Struct.Mol.Biol., 20, 2013
4V9H
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CRYSTAL STRUCTURE OF THE RIBOSOME BOUND TO ELONGATION FACTOR G IN THE GUANOSINE TRIPHOSPHATASE STATE
Descriptor:Ribosome
Authors:Tourigny, D.S., Fernandez, I.S., Kelley, A.C., Ramakrishnan, V.
Deposit date:2013-03-25
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (2.857 Å)
Cite:Elongation factor G bound to the ribosome in an intermediate state of translocation.
Science, 340, 2013
5IQR
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STRUCTURE OF RELA BOUND TO THE 70S RIBOSOME
Descriptor:50S ribosomal protein L2, 50S ribosomal protein L3, 50S ribosomal protein L4, 50S ribosomal protein L5, 50S ribosomal protein L6, 50S ribosomal protein L9, 50S ribosomal protein L10, 50S ribosomal protein L11, 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L15, 50S ribosomal protein L16, 50S ribosomal protein L17, 50S ribosomal protein L18, 50S ribosomal protein L19, 50S ribosomal protein L20, 50S ribosomal protein L21, 50S ribosomal protein L22, 50S ribosomal protein L23, 50S ribosomal protein L24, 50S ribosomal protein L25, 50S ribosomal protein L27, 50S ribosomal protein L28, 50S ribosomal protein L29, 50S ribosomal protein L30, 50S ribosomal protein L31, 50S ribosomal protein L32, 50S ribosomal protein L33, 50S ribosomal protein L34, 50S ribosomal protein L35, 50S ribosomal protein L36, 30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, 30S ribosomal protein S5, 30S ribosomal protein S6, 30S ribosomal protein S7, 30S ribosomal protein S8, 30S ribosomal protein S9, 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, 30S ribosomal protein S13, 30S ribosomal protein S14, 30S ribosomal protein S15, 30S ribosomal protein S16, 30S ribosomal protein S17, 30S ribosomal protein S18, 30S ribosomal protein S19, 30S ribosomal protein S20, 30S ribosomal protein S21, GTP pyrophosphokinase/RNA Complex
Authors:Brown, A., Fernandez, I.S., Gordiyenko, Y., Ramakrishnan, V.
Deposit date:2016-03-11
Release date:2016-05-04
Last modified:2016-09-28
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Ribosome-dependent activation of stringent control.
Nature, 534, 2016
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