Author results

3CUO
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CRYSTAL STRUCTURE OF THE PREDICTED DNA-BINDING TRANSCRIPTIONAL REGULATOR FROM E. COLI
分子名称:Uncharacterized HTH-type transcriptional regulator ygaV
著者Zhang, R., Evdokimova, E., Kagan, O., Savchenko, A., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2008-04-16
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The crystal structure of the predicted DNA-binding transcriptional regulator from E. coli.
To be Published
3HFU
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CRYSTAL STRUCTURE OF THE LIGAND BINDING DOMAIN OF E. COLI CYNR WITH ITS SPECIFIC EFFECTOR AZIDE
分子名称:HTH-type transcriptional regulator cynR, AZIDE ION, 1,2-ETHANEDIOL
著者Singer, A.U., Evdokimova, E., Kagan, O., Dong, A., Edwards, A.M., Savchenko, A.
登録日2009-05-12
公開日2009-06-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the ligand binding domain of E. coli CynR with its specific effector azide
TO BE PUBLISHED
1RYL
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THE CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION YFBM FROM ESCHERICHIA COLI
分子名称:Hypothetical protein yfbM
著者Zhang, R., Evdokimova, E., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2003-12-22
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献1.6A crystal structure of a hypothetical protein yfbM from E. coli
To be Published
1YOC
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CRYSTAL STRUCTURE OF GENOMICS APC5556
分子名称:hypothetical protein PA1835, GLYCEROL
著者Dong, A., Evdokimova, E., Kudritskam, M., Zhang, R.G., Yakunin, A., Pai, E., Edwards, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2005-01-27
公開日2005-03-08
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of genomics AFPA1835 by Sulfur SAD methods
To be Published
3BRQ
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CRYSTAL STRUCTURE OF THE ESCHERICHIA COLI TRANSCRIPTIONAL REPRESSOR ASCG
分子名称:HTH-type transcriptional regulator ascG, FRUCTOSE, SULFATE ION, ...
著者Singer, A.U., Kagan, O., Evdokimova, E., Osipiuk, J., Joachimiak, A., Edwards, A.M., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2007-12-21
公開日2008-01-22
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the E. coli transcriptional repressor ascG.
To be Published
3HHL
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CRYSTAL STRUCTURE OF METHYLATED RPA0582 PROTEIN
分子名称:RPA0582, SULFATE ION, CHLORIDE ION, ...
著者Sledz, P., Niedzialkowska, E., Chruszcz, M., Porebski, P., Yim, V., Kudritska, M., Zimmerman, M.D., Evdokimova, E., Savchenko, A., Edwards, A., Joachimiak, A., Minor, W., Midwest Center for Structural Genomics (MCSG)
登録日2009-05-15
公開日2009-07-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal structure of methylated RPA0582 protein
To be Published
3UZR
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(2'')-IB, APO FORM
分子名称:Aminoglycoside phosphotransferase, MAGNESIUM ION, 1,2-ETHANEDIOL, ...
著者Stogios, P.J., Minasov, G., Singer, A.U., Tan, K., Nocek, B., Evdokimova, E., Egorova, E., Di Leo, R., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-12-07
公開日2011-12-21
最終更新日2011-12-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of aminoglycoside phosphotransferase APH(2'')-Ib, apo form
TO BE PUBLISHED
1SU1
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STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF YFCE, A PHOSPHOESTERASE FROM E. COLI
分子名称:Hypothetical protein yfcE, ZINC ION, SULFATE ION
著者Miller, D.J., Shuvalova, L., Evdokimova, E., Savchenko, A., Yakunin, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
登録日2004-03-25
公開日2004-08-17
最終更新日2018-10-03
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and biochemical characterization of a novel Mn2+-dependent phosphodiesterase encoded by the yfcE gene.
Protein Sci., 16, 2007
1YSP
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CRYSTAL STRUCTURE OF THE C-TERMINAL DOMAIN OF E. COLI TRANSCRIPTIONAL REGULATOR KDGR.
分子名称:Transcriptional regulator kdgR, SULFATE ION
著者Bochkarev, A., Lunin, V.V., Ezersky, A., Evdokimova, E., Skarina, T., Xu, X., Borek, D., Joachimiak, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2005-02-08
公開日2005-03-22
最終更新日2011-10-05
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of effector binding specificity in IclR transcriptional regulators
To be Published
2HXR
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STRUCTURE OF THE LIGAND BINDING DOMAIN OF E. COLI CYNR, A TRANSCRIPTIONAL REGULATOR CONTROLLING CYANATE METABOLISM
分子名称:HTH-type transcriptional regulator cynR
著者Singer, A.U., Cuff, M.E., Evdokimova, E., Kagan, O., Joachimiak, A., Edwards, A.M., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2006-08-03
公開日2006-08-22
最終更新日2017-10-18
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献The structure of CynR, a transcriptional regulator, both in the presence and absence of sodium azide, its activator ligand
To be Published
4DBX
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(2")-ID/APH(2")-IVA
分子名称:APH(2")-ID
著者Stogios, P.J., Minasov, G., Tan, K., Nocek, B., Singer, A.U., Evdokimova, E., Egorova, E., Di Leo, R., Li, H., Shakya, T., Wright, G.D., Savchenko, A., Anderson, W.F., Midwest Center for Structural Genomics (MCSG)
登録日2012-01-16
公開日2012-02-01
最終更新日2012-04-25
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
4DFB
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(2")-ID/APH(2")-IVA IN COMPLEX WITH KANAMYCIN
分子名称:APH(2")-Id, KANAMYCIN A, CHLORIDE ION
著者Stogios, P.J., Minasov, G., Osipiuk, J., Evdokimova, E., Egorova, E., Di leo, R., Li, H., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-01-23
公開日2012-02-08
最終更新日2012-10-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
4DFU
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INHIBITION OF AN ANTIBIOTIC RESISTANCE ENZYME: CRYSTAL STRUCTURE OF AMINOGLYCOSIDE PHOSPHOTRANSFERASE APH(2")-ID/APH(2")-IVA IN COMPLEX WITH KANAMYCIN INHIBITED WITH QUERCETIN
分子名称:APH(2")-Id, KANAMYCIN A, 3,5,7,3',4'-PENTAHYDROXYFLAVONE, ...
著者Stogios, P.J., Minasov, G., Dong, A., Evdokimova, E., Egorova, E., Di Leo, R., Li, H., Shakya, T., Wright, G.D., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-01-24
公開日2012-02-08
最終更新日2012-02-22
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A small molecule discrimination map of the antibiotic resistance kinome.
Chem.Biol., 18, 2011
5US1
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CRYSTAL STRUCTURE OF AMINOGLYCOSIDE ACETYLTRANSFERASE AAC(2')-IA IN COMPLEX WITH N2'-ACETYLGENTAMICIN C1A AND COENZYME A
分子名称:Aminoglycoside 2'-N-acetyltransferase, (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-(acetylamino)-6-amino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranoside, D(-)-TARTARIC ACID, ...
著者Stogios, P.J., Evdokimova, E., Xu, Z., Wawrzak, Z., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2017-02-13
公開日2017-03-15
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.
ACS Infect Dis, 4, 2018
6CD7
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CRYSTAL STRUCTURE OF APH(2")-IVA IN COMPLEX WITH PLAZOMICIN
分子名称:APH(2'')-Id, CHLORIDE ION, (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-{[(2S,3R)-3-amino-6-{[(2-hydroxyethyl)amino]methyl}-3,4-dihydro-2H-pyran-2-yl]oxy}-2-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide
著者Stogios, P.J., Evdokimova, E., Dong, A., Di Leo, R., Savchenko, A., Satchell, K.J., Joachimiak, J., Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2018-02-08
公開日2018-02-28
最終更新日2018-06-20
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.
ACS Infect Dis, 4, 2018
1KTN
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STRUCTURAL GENOMICS, PROTEIN EC1535
分子名称:2-deoxyribose-5-phosphate aldolase
著者Zhang, R., Joachimiak, A., Edwards, A., Skarina, T., Evdokimova, E., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2002-01-16
公開日2002-08-14
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献The 1.5A crystal structure of 2-deoxyribose-5-phosphate aldlase
To be Published
1KXJ
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THE CRYSTAL STRUCTURE OF GLUTAMINE AMIDOTRANSFERASE FROM THERMOTOGA MARITIMA
分子名称:Amidotransferase hisH, PHOSPHATE ION
著者Korolev, S., Skarina, T., Evdokimova, E., Beasley, S., Edwards, A., Joachimiak, A., Savchenko, A., Midwest Center for Structural Genomics (MCSG)
登録日2002-01-31
公開日2002-03-20
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of glutamine amidotransferase from Thermotoga maritima
Proteins, 49, 2002
1NN4
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STRUCTURAL GENOMICS, RPIB/ALSB
分子名称:Ribose 5-phosphate isomerase B
著者Zhang, R.G., Andersson, C.E., Mowbray, S.L., Savchenko, A., Skarina, T., Evdokimova, E., Beasley, S.L., Arrowsmith, C., Edwards, A.M., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2003-01-12
公開日2003-07-29
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The 2.2 A resolution structure of RpiB/AlsB from Escherichia coli illustrates a new approach to the ribose-5-phosphate isomerase reaction.
J.Mol.Biol., 332, 2003
1O8B
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STRUCTURE OF ESCHERICHIA COLI RIBOSE-5-PHOSPHATE ISOMERASE, RPIA, COMPLEXED WITH ARABINOSE-5-PHOSPHATE.
分子名称:RIBOSE 5-PHOSPHATE ISOMERASE, BETA-D-ARABINOFURANOSE-5'-PHOSPHATE
著者Zhang, R.-g., Andersson, C.E., Savchenko, A., Skarina, T., Evdokimova, E., Beasley, S., Arrowsmith, C.H., Edwards, A.M., Joachimiak, A., Mowbray, S.L., Midwest Center for Structural Genomics (MCSG)
登録日2002-11-26
公開日2003-01-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structure of Escherichia Coli Ribose-5-Phosphate Isomerase: A Ubiquitous Enzyme of the Pentose Phosphate Pathway and the Calvin Cycle
Structure, 11, 2003
1P9Q
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STRUCTURE OF A HYPOTHETICAL PROTEIN AF0491 FROM ARCHAEOGLOBUS FULGIDUS
分子名称:Hypothetical protein AF0491
著者Savchenko, A., Evdokimova, E., Skarina, T., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A.
登録日2003-05-12
公開日2004-06-08
最終更新日2018-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Shwachman-Bodian-Diamond syndrome protein family is involved in RNA metabolism.
J.Biol.Chem., 280, 2005
1QW2
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CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION TA1206 FROM THERMOPLASMA ACIDOPHILUM
分子名称:conserved hypothetical protein TA1206
著者Savchenko, A., Evdokimova, E., Kudrytska, M., Edwards, A.E., Christendat, D., Midwest Center for Structural Genomics (MCSG)
登録日2003-08-30
公開日2004-03-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal Structure of a Hypothetical Protein "TA1206" from Thermoplasma acidophilum
To be Published
1RLK
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STRUCTURE OF CONSERVED PROTEIN OF UNKNOWN FUNCTION TA0108 FROM THERMOPLASMA ACIDOPHILUM
分子名称:Hypothetical protein Ta0108, SULFATE ION, GLYCEROL
著者Osipiuk, J., Evdokimova, E., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2003-11-25
公開日2003-12-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structure of conserved hypothetical protein TA0108 from Thermoplasma acidophilum
To be Published
1SED
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CRYSTAL STRUCTURE OF PROTEIN OF UNKNOWN FUNCTION YHAL FROM BACILLUS SUBTILIS
分子名称:Hypothetical protein yhaI, ZINC ION, SODIUM ION, ...
著者Kim, Y., Joachimiak, A., Evdokimova, E., Savchenko, A., Edwards, A., Midwest Center for Structural Genomics (MCSG)
登録日2004-02-17
公開日2004-05-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The Crystal Structure of the Hypothetical Protein YhaI, APC1180 from Bacillus subtilis
To be Published
1SH8
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1.5 A CRYSTAL STRUCTURE OF A PROTEIN OF UNKNOWN FUNCTION PA5026 FROM PSEUDOMONAS AERUGINOSA, PROBABLE THIOESTERASE
分子名称:hypothetical protein PA5026
著者Zhang, R., Evdokimova, E., Savchenko, A., Edwards, A., Joachimiak, A., Midwest Center for Structural Genomics (MCSG)
登録日2004-02-25
公開日2004-07-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献1.5A crystal structure of a hypothetical protein PA5026 from Pseudomonas aeruginosa
To be Published
1TE2
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PUTATIVE PHOSPHATASE YNIC FROM ESCHERICHIA COLI K12
分子名称:2-deoxyglucose-6-P phosphatase, 2-PHOSPHOGLYCOLIC ACID, CALCIUM ION
著者Kim, Y., Joachimiak, A., Evdokimova, E., Savchenko, A., Edwards, A., Midwest Center for Structural Genomics (MCSG)
登録日2004-05-24
公開日2004-08-03
最終更新日2015-06-24
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Crystal Structure of Putative Phosphatase Ynic from Escherichia coli K12
To be Published