6BNE

Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, phosphate-bound complex

Summary for 6BNE

• Entry DOI: 10.2210/pdb6bne/pdb
• Related: 6BNC 6BND 6BNF
• Descriptor: Phosphoethanolamine transferase, SULFATE ION, GLYCEROL, ... (6 entities in total)
• Functional Keywords: antibiotic resistance, colistin, polymycin, phosphoethanolamine transferase, sulfatase fold, alpha/beta protein, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
• Biological source: Moraxella sp. HMSC061H09
• Total number of polymer chains: 1
• Total formula weight: 38505.67

Authors

Stogios, P.J.,Evdokimova, E.,Wawrzak, Z.,Di Leo, R.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-11-16, release date: 2018-01-31, Last modification date: 2023-10-04)

• Primary citation: Stogios, P.J.,Cox, G.,Zubyk, H.L.,Evdokimova, E.,Wawrzak, Z.,Wright, G.D.,Savchenko, A.; Substrate recognition by a colistin resistance enzyme from Moraxella catarrhalis.; ACS Chem. Biol., 2018; PubMed: 29631403; DOI: 10.1021/acschembio.8b00116

Experimental method

X-RAY DIFFRACTION (2.61 Å)