6BND
Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, Thr315Ala mutant mono-zinc and phosphoethanolamine complex
Summary for 6BND
Entry DOI | 10.2210/pdb6bnd/pdb |
Related | 6BNC 6BNE 6BNF |
Descriptor | Phosphoethanolamine transferase, ZINC ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... (6 entities in total) |
Functional Keywords | antibiotic resistance, colistin, polymyxin, phosphoethanolamine transferase, sulfatase fold, alpha/beta protein, structural genomics, center for structural genomics of infectious diseases, csgid, transferase |
Biological source | Moraxella sp. HMSC061H09 |
Total number of polymer chains | 2 |
Total formula weight | 80981.19 |
Authors | Stogios, P.J.,Evdokimova, E.,Wawrzak, Z.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-11-16, release date: 2018-01-31, Last modification date: 2023-10-04) |
Primary citation | Stogios, P.J.,Cox, G.,Zubyk, H.L.,Evdokimova, E.,Wawrzak, Z.,Wright, G.D.,Savchenko, A. Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis. ACS Chem. Biol., 13:1322-1332, 2018 Cited by PubMed: 29631403DOI: 10.1021/acschembio.8b00116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.66 Å) |
Structure validation
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