6BND

Crystal structure of the intrinsic colistin resistance enzyme ICR(Mc) from Moraxella catarrhalis, catalytic domain, Thr315Ala mutant mono-zinc and phosphoethanolamine complex

Summary for 6BND

Entry DOI	10.2210/pdb6bnd/pdb
Related	6BNC 6BNE 6BNF
Descriptor	Phosphoethanolamine transferase, ZINC ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... (6 entities in total)
Functional Keywords	antibiotic resistance, colistin, polymyxin, phosphoethanolamine transferase, sulfatase fold, alpha/beta protein, structural genomics, center for structural genomics of infectious diseases, csgid, transferase
Biological source	Moraxella sp. HMSC061H09
Total number of polymer chains	2
Total formula weight	80981.19
Authors	Stogios, P.J.,Evdokimova, E.,Wawrzak, Z.,Savchenko, A.,Anderson, W.F.,Satchell, K.J.,Joachimiak, A.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2017-11-16, release date: 2018-01-31, Last modification date: 2023-10-04)
Primary citation	Stogios, P.J.,Cox, G.,Zubyk, H.L.,Evdokimova, E.,Wawrzak, Z.,Wright, G.D.,Savchenko, A. Substrate Recognition by a Colistin Resistance Enzyme from Moraxella catarrhalis. ACS Chem. Biol., 13:1322-1332, 2018 Cited by PubMed: 29631403 DOI: 10.1021/acschembio.8b00116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation