6U69

Crystal structure of Yck2 from Candida albicans, apoenzyme

Summary for 6U69

Entry DOI	10.2210/pdb6u69/pdb
Descriptor	Serine/threonine protein kinase, SULFATE ION, GLYCEROL, ... (5 entities in total)
Functional Keywords	casein kinase 1, yck2, kinase, structural genomics, center for structural genomics of infectious diseases, niaid, national institute of allergy and infectious diseases, csgid, transferase
Biological source	Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Total number of polymer chains	1
Total formula weight	35620.86
Authors	Stogios, P.J.,Evdokimova, E.,Di Leo, R.,Savchenko, A.,Joachimiak, A.,Satchell, K.J.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2019-08-29, release date: 2019-10-09, Last modification date: 2023-10-11)
Primary citation	Caplan, T.,Lorente-Macias, A.,Stogios, P.J.,Evdokimova, E.,Hyde, S.,Wellington, M.A.,Liston, S.,Iyer, K.R.,Puumala, E.,Shekhar-Guturja, T.,Robbins, N.,Savchenko, A.,Krysan, D.J.,Whitesell, L.,Zuercher, W.J.,Cowen, L.E. Overcoming Fungal Echinocandin Resistance through Inhibition of the Non-essential Stress Kinase Yck2. Cell Chem Biol, 27:269-282.e5, 2020 Cited by PubMed: 31924499 DOI: 10.1016/j.chembiol.2019.12.008 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.61 Å)

Structure validation