6AOK
Crystal structure of Legionella pneumophila effector Ceg4 with N-terminal TEV protease cleavage sequence
Summary for 6AOK
Entry DOI | 10.2210/pdb6aok/pdb |
Related | 6AOJ |
Descriptor | Ceg4, MAGNESIUM ION, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | effector, legionella pneumophila, infection, had-like phosphatase, alpha/beta protein, phosphotyrosine, hydrolase |
Biological source | Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513) |
Total number of polymer chains | 1 |
Total formula weight | 25833.95 |
Authors | Stogios, P.J.,Cuff, M.E.,Nocek, B.,Evdokimova, E.,Egorova, O.,Yim, V.,Di Leo, R.,Savchenko, A. (deposition date: 2017-08-16, release date: 2018-01-10, Last modification date: 2018-03-28) |
Primary citation | Quaile, A.T.,Stogios, P.J.,Egorova, O.,Evdokimova, E.,Valleau, D.,Nocek, B.,Kompella, P.S.,Peisajovich, S.,Yakunin, A.F.,Ensminger, A.W.,Savchenko, A. TheLegionella pneumophilaeffector Ceg4 is a phosphotyrosine phosphatase that attenuates activation of eukaryotic MAPK pathways. J. Biol. Chem., 293:3307-3320, 2018 Cited by PubMed: 29301934DOI: 10.1074/jbc.M117.812727 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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