Author results

1D5S
  • Download 1d5s
  • View 1d5s
Molmil generated image of 1d5s
CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER
Descriptor:P1-ARG ANTITRYPSIN
Authors:Dunstone, M.A., Dai, W., Whisstock, J.C., Rossjohn, J., Pike, R.N., Feil, S.C., Le Bonneic, B.F., Parker, M.W., Bottomley, S.P.
Deposit date:1999-10-11
Release date:2000-04-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
4OEB
  • Download 4oeb
  • View 4oeb
Molmil generated image of 4oeb
STRUCTURE OF MEMBRANE BINDING PROTEIN PLEUROTOLYSIN A FROM PLEUROTUS OSTREATUS
Descriptor:Pleurotolysin A, SULFATE ION
Authors:Dunstone, M.A., Caradoc-Davies, T.T., Whisstock, J.C., Law, R.H.P.
Deposit date:2014-01-12
Release date:2015-02-18
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4OEJ
  • Download 4oej
  • View 4oej
Molmil generated image of 4oej
STRUCTURE OF MEMBRANE BINDING PROTEIN PLEUROTOLYSIN B FROM PLEUROTUS OSTREATUS
Descriptor:Pleurotolysin B, ACETATE ION, GLYCEROL, ...
Authors:Dunstone, M.A., Caradoc-Davies, T.T., Whisstock, J.C., Law, R.H.P.
Deposit date:2014-01-13
Release date:2015-02-18
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
6DLW
  • Download 6dlw
  • View 6dlw
Molmil generated image of 6dlw
COMPLEMENT COMPONENT POLYC9
Descriptor:Complement component C9, N-ACETYL-D-GLUCOSAMINE, BETA-D-MANNOSE
Authors:Dunstone, M.A., Spicer, B.A., Law, R.H.P.
Deposit date:2018-06-03
Release date:2018-09-12
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
1S9W
  • Download 1s9w
  • View 1s9w
Molmil generated image of 1s9w
CRYSTAL STRUCTURE ANALYSIS OF NY-ESO-1 EPITOPE, SLLMWITQC, IN COMPLEX WITH HLA-A2
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Webb, A.I., Dunstone, M.A., Chen, W., Aguilar, M.I., Chen, Q., Chang, L., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Rossjohn, J., Purcell, A.W.
Deposit date:2004-02-05
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004
1S9X
  • Download 1s9x
  • View 1s9x
Molmil generated image of 1s9x
CRYSTAL STRUCTURE ANALYSIS OF NY-ESO-1 EPITOPE ANALOGUE, SLLMWITQA, IN COMPLEX WITH HLA-A2
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Webb, A.I., Dunstone, M.A., Chen, W., Aguilar, M.I., Chen, Q., Chang, L., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Rossjohn, J., Purcell, A.W.
Deposit date:2004-02-05
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004
1S9Y
  • Download 1s9y
  • View 1s9y
Molmil generated image of 1s9y
CRYSTAL STRUCTURE ANALYSIS OF NY-ESO-1 EPITOPE ANALOGUE, SLLMWITQS, IN COMPLEX WITH HLA-A2
Descriptor:HLA class I histocompatibility antigen, A-2 alpha chain, Beta-2-microglobulin, ...
Authors:Webb, A.I., Dunstone, M.A., Chen, W., Aguilar, M.I., Chen, Q., Chang, L., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Rossjohn, J., Purcell, A.W.
Deposit date:2004-02-05
Release date:2004-09-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Functional and structural characteristics of NY-ESO-1-related HLA A2-restricted epitopes and the design of a novel immunogenic analogue
J.Biol.Chem., 279, 2004
1SY6
  • Download 1sy6
  • View 1sy6
Molmil generated image of 1sy6
CRYSTAL STRUCTURE OF CD3GAMMAEPSILON HETERODIMER IN COMPLEX WITH OKT3 FAB FRAGMENT
Descriptor:OKT3 Fab light chain, OKT3 Fab heavy chain, T-cell surface glycoprotein CD3 gamma/epsilon chain
Authors:Kjer-Nielsen, L., Dunstone, M.A., Kostenko, L., Ely, L.K., Beddoe, T., Misfud, N.A., Purcell, A.W., Brooks, A.G., McCluskey, J., Rossjohn, J.
Deposit date:2004-03-31
Release date:2004-05-25
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of the human T cell receptor CD3(epsilon)(gamma) heterodimer complexed to the therapeutic mAb OKT3.
Proc.Natl.Acad.Sci.USA, 101, 2004
1T0M
  • Download 1t0m
  • View 1t0m
Molmil generated image of 1t0m
CONFORMATIONAL SWITCH IN POLYMORPHIC H-2K MOLECULES CONTAINING AN HSV PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Webb, A.I., Borg, N.A., Dunstone, M.A., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Carbone, F.R., Bottomley, S.P., Purcell, A.W., Rossjohn, J.
Deposit date:2004-04-12
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance
J.Immunol., 173, 2004
1T0N
  • Download 1t0n
  • View 1t0n
Molmil generated image of 1t0n
CONFORMATIONAL SWITCH IN POLYMORPHIC H-2K MOLECULES CONTAINING AN HSV PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Webb, A.I., Borg, N.A., Dunstone, M.A., Kjer-Nielsen, L., Beddoe, T., McCluskey, J., Carbone, F.R., Bottomley, S.P., Purcell, A.W., Rossjohn, J.
Deposit date:2004-04-12
Release date:2004-11-23
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance
J.Immunol., 173, 2004
1YDP
  • Download 1ydp
  • View 1ydp
Molmil generated image of 1ydp
1.9A CRYSTAL STRUCTURE OF HLA-G
Descriptor:MHC class I antigen, Beta-2-microglobulin, histone 2a peptide, ...
Authors:Clements, C.S., Kjer-nielsen, L., Kostenko, L., Hoare, H.L., Dunstone, M.A., Moses, E., Freed, K., Brooks, A.G., Rossjohn, J., Mccluskey, J.
Deposit date:2004-12-25
Release date:2005-03-08
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure of HLA-G: A nonclassical MHC class I molecule expressed at the fetal-maternal interface
PROC.NATL.ACAD.SCI.USA, 102, 2005
1YN6
  • Download 1yn6
  • View 1yn6
Molmil generated image of 1yn6
CRYSTAL STRUCTURE OF A MOUSE MHC CLASS I PROTEIN, H2-DB, IN COMPLEX WITH A PEPTIDE FROM THE INFLUENZA A ACID POLYMERASE
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Turner, S.J., Kedzierska, K., Komodromou, H., La Gruta, N.L., Dunstone, M.A., Webb, A.I., Webby, R., Walden, H., Xie, W., McCluskey, J., Purcell, A.W., Rossjohn, J., Doherty, P.C.
Deposit date:2005-01-23
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
1YN7
  • Download 1yn7
  • View 1yn7
Molmil generated image of 1yn7
CRYSTAL STRUCTURE OF A MOUSE MHC CLASS I PROTEIN, H2-DB, IN COMPLEX WITH A MUTATED PEPTIDE (R7A) OF THE INFLUENZA A ACID POLYMERASE
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Turner, S.J., Kedzierska, K., Komodromou, H., La Gruta, N.L., Dunstone, M.A., Webb, A.I., Webby, R., Walden, H., Xie, W., McCluskey, J., Purcell, A.W., Rossjohn, J., Doherty, P.C.
Deposit date:2005-01-24
Release date:2005-06-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Lack of prominent peptide-major histocompatibility complex features limits repertoire diversity in virus-specific CD8+ T cell populations
Nat.Immunol., 6, 2005
2QP2
  • Download 2qp2
  • View 2qp2
Molmil generated image of 2qp2
STRUCTURE OF A MACPF/PERFORIN-LIKE PROTEIN
Descriptor:Unknown protein, CALCIUM ION
Authors:Rosado, C.J., Buckle, A.M., Law, R.H.P., Butcher, R.E., Kan, W.T., Bird, C.H., Ung, K., Browne, K.A., Baran, K., Bashtannyk-Puhalovich, T.A., Faux, N.G., Wong, W., Porter, C.J., Pike, R.N., Ellisdon, A.M., Pearce, M.C., Bottomley, S.P., Emsley, J., Smith, A.I., Rossjohn, J., Hartland, E.L., Voskoboinik, I., Trapani, J.A., Bird, P.I., Dunstone, M.A., Whisstock, J.C.
Deposit date:2007-07-22
Release date:2007-09-04
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (2 Å)
Cite:A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
2ZOK
  • Download 2zok
  • View 2zok
Molmil generated image of 2zok
CRYSTAL STRUCTURE OF H-2DB IN COMPLEX WITH JHMV EPITOPE S510
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Theodossis, A., Dunstone, M.A., Rossjohn, J.
Deposit date:2008-05-22
Release date:2008-06-10
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and biological basis of CTL escape in coronavirus-infected mice
J.Immunol., 180, 2008
2ZOL
  • Download 2zol
  • View 2zol
Molmil generated image of 2zol
CRYSTAL STRUCTURE OF H-2DB IN COMPLEX WITH THE W513S VARIANT OF JHMV EPITOPE S510
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Theodossis, A., Dunstone, M.A., Rossjohn, J.
Deposit date:2008-05-22
Release date:2008-06-10
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and biological basis of CTL escape in coronavirus-infected mice
J.Immunol., 180, 2008
2ZSV
  • Download 2zsv
  • View 2zsv
Molmil generated image of 2zsv
CRYSTAL STRUCTURE OF H-2KB IN COMPLEX WITH JHMV EPITOPE S598
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Theodossis, A., Dunstone, M.A., Rossjohn, J.
Deposit date:2008-09-18
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant.
Plos Pathog., 4, 2008
2ZSW
  • Download 2zsw
  • View 2zsw
Molmil generated image of 2zsw
CRYSTAL STRUCTURE OF H-2KB IN COMPLEX WITH THE Q600Y VARIANT OF JHMV EPITOPE S598
Descriptor:H-2 class I histocompatibility antigen, K-B alpha chain, Beta-2-microglobulin, ...
Authors:Theodossis, A., Dunstone, M.A., Rossjohn, J.
Deposit date:2008-09-18
Release date:2008-11-04
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant.
Plos Pathog., 4, 2008
3BUY
  • Download 3buy
  • View 3buy
Molmil generated image of 3buy
MHC-I IN COMPLEX WITH PEPTIDE
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Rossjohn, J., La Gruta, N.L., Purcell, A.W., Turner, S.J., Dunstone, M.A.
Deposit date:2008-01-03
Release date:2008-03-25
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Epitope-specific TCRbeta repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides
Proc.Natl.Acad.Sci.Usa, 105, 2008
3L3H
  • Download 3l3h
  • View 3l3h
Molmil generated image of 3l3h
X-RAY CRYSTAL STRUCTURE OF THE F6A MUTANT OF INFLUENZA A ACID POLYMERASE EPITOPE PA224 BOUND TO MURINE H2-DB MHC
Descriptor:H-2 class I histocompatibility antigen, D-B alpha chain, Beta-2-microglobulin, ...
Authors:Welland, A., Clements, C.S., Dunstone, M.A., Rossjohn, J.
Deposit date:2009-12-17
Release date:2010-03-16
Last modified:2014-02-26
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
4OV8
  • Download 4ov8
  • View 4ov8
Molmil generated image of 4ov8
CRYSTAL STRUCTURE OF THE TMH1-LOCK MUTANT OF THE MATURE FORM OF PLEUROTOLYSIN B
Descriptor:Pleurotolysin B, SULFATE ION, CHLORIDE ION, ...
Authors:Kondos, S.C., Law, R.H.P., Whisstock, J.C., Dunstone, M.A.
Deposit date:2014-02-20
Release date:2015-02-18
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
Plos Biol., 13, 2015
4V2T
  • Download 4v2t
  • View 4v2t
Molmil generated image of 4v2t
MEMBRANE EMBEDDED PLEUROTOLYSIN PORE WITH 13 FOLD SYMMETRY
Descriptor:PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N., Kondos, S.C., Farabella, I., Law, R.H.P., Reboul, C.F., Caradoc-Davies, T.T., Spicer, B.A., Kleifeld, O., Perugini, M., Ekkel, S., Hatfaludi, T., Oliver, K., Hotze, E.M., Tweten, R.K., Whisstock, J.C., Topf, M., Dunstone, M.A., Saibil, H.R.
Deposit date:2014-10-15
Release date:2015-02-18
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (11 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3A
  • Download 4v3a
  • View 4v3a
Molmil generated image of 4v3a
MEMBRANE BOUND PLEUROTOLYSIN PREPORE (TMH1 LOCK) TRAPPED WITH ENGINEERED DISULPHIDE CROSS-LINK
Descriptor:PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N., Kondos, S.C., Farabella, I., Law, R.H.P., Reboul, C.F., CaradocDavies, T.T., Spicer, B.A., Kleifeld, O., Perugini, M., Ekkel, S., Hatfaludi, T., Oliver, K., Hotze, E.M., Tweten, R.K., Whisstock, J.C., Topf, M., Dunstone, M.A., Saibil, H.R.
Deposit date:2014-10-17
Release date:2015-02-18
Last modified:2017-08-30
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3M
  • Download 4v3m
  • View 4v3m
Molmil generated image of 4v3m
MEMBRANE BOUND PLEUROTOLYSIN PREPORE (TMH2 HELIX LOCK) TRAPPED WITH ENGINEERED DISULPHIDE CROSS-LINK
Descriptor:PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N., Kondos, S.C., Farabella, I., Law, R.H.P., Reboul, C.F., Caradoc-Davies, T.T., Spicer, B.A., Kleifeld, O., Perugini, M., Ekkel, S., Hatfaludi, T., Oliver, K., Hotze, E.M., Tweten, R.K., Whisstock, J.C., Topf, M., Dunstone, M.A., Saibil, H.R.
Deposit date:2014-10-20
Release date:2015-02-18
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (17 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3N
  • Download 4v3n
  • View 4v3n
Molmil generated image of 4v3n
MEMBRANE BOUND PLEUROTOLYSIN PREPORE (TMH2 STRAND LOCK) TRAPPED WITH ENGINEERED DISULPHIDE CROSS-LINK
Descriptor:PLEUROTOLYSIN A, PLEUROTOLYSIN B
Authors:Lukoyanova, N., Kondos, S.C., Farabella, I., Law, R.H.P., Reboul, C.F., Caradoc-Davies, T.T., Spicer, B.A., Kleifeld, O., Perugini, M., Ekkel, S., Hatfaludi, T., Oliver, K., Hotze, E.M., Tweten, R.K., Whisstock, J.C., Topf, M., Dunstone, M.A., Saibil, H.R.
Deposit date:2014-10-20
Release date:2015-02-18
Last modified:2017-08-23
Method:ELECTRON MICROSCOPY (14 Å)
Cite:Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
<12>