4V3N
Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link
Summary for 4V3N
Entry DOI | 10.2210/pdb4v3n/pdb |
Related | 4V2T 4V3A 4V3M |
EMDB information | 2796 |
Descriptor | PLEUROTOLYSIN A, PLEUROTOLYSIN B (2 entities in total) |
Functional Keywords | transport protein, macpf/cdc superfamily, pore-forming proteins |
Biological source | PLEUROTUS OSTREATUS (OYSTER MUSHROOM) More |
Total number of polymer chains | 3 |
Total formula weight | 72615.75 |
Authors | Lukoyanova, N.,Kondos, S.C.,Farabella, I.,Law, R.H.P.,Reboul, C.F.,Caradoc-Davies, T.T.,Spicer, B.A.,Kleifeld, O.,Perugini, M.,Ekkel, S.,Hatfaludi, T.,Oliver, K.,Hotze, E.M.,Tweten, R.K.,Whisstock, J.C.,Topf, M.,Dunstone, M.A.,Saibil, H.R. (deposition date: 2014-10-20, release date: 2015-02-18, Last modification date: 2024-05-08) |
Primary citation | Lukoyanova, N.,Kondos, S.C.,Farabella, I.,Law, R.H.P.,Reboul, C.F.,Caradoc-Davies, T.T.,Spicer, B.A.,Kleifeld, O.,Traore, D.A.K.,Ekkel, S.M.,Voskoboinik, I.,Trapani, J.A.,Hatfaludi, T.,Oliver, K.,Hotze, E.M.,Tweten, R.K.,Whisstock, J.C.,Topf, M.,Saibil, H.R.,Dunstone, M.A. Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin. Plos Biol., 13:02049-, 2015 Cited by PubMed: 25654333DOI: 10.1371/JOURNAL.PBIO.1002049 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (14 Å) |
Structure validation
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