4OV8

Crystal Structure of the TMH1-lock mutant of the mature form of pleurotolysin B

Summary for 4OV8

Entry DOI	10.2210/pdb4ov8/pdb
Descriptor	Pleurotolysin B, SULFATE ION, CHLORIDE ION, ... (5 entities in total)
Functional Keywords	tmh1-lock, macpf domain, pore-forming protein, pleurtolysin a component, toxin
Biological source	Pleurotus ostreatus (Oyster mushroom)
Total number of polymer chains	1
Total formula weight	52656.41
Authors	Kondos, S.C.,Law, R.H.P.,Whisstock, J.C.,Dunstone, M.A. (deposition date: 2014-02-20, release date: 2015-02-18, Last modification date: 2023-11-08)
Primary citation	Lukoyanova, N.,Kondos, S.C.,Farabella, I.,Law, R.H.P.,Reboul, C.F.,Caradoc-Davies, T.T.,Spicer, B.A.,Kleifeld, O.,Traore, D.A.,Ekkel, S.M.,Voskoboinik, I.,Trapani, J.A.,Hatfaludi, T.,Oliver, K.,Hotze, E.M.,Tweten, R.K.,Whisstock, J.C.,Topf, M.,Saibil, H.R.,Dunstone, M.A. Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin Plos Biol., 13:e1002049-e1002049, 2015 Cited by PubMed: 25654333 DOI: 10.1371/journal.pbio.1002049 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation