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4INS
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THE STRUCTURE OF 2ZN PIG INSULIN CRYSTALS AT 1.5 ANGSTROMS RESOLUTION
Descriptor:INSULIN (CHAIN A), INSULIN (CHAIN B), ZINC ION
Authors:Dodson, G.G., Dodson, E.J., Hodgkin, D.C., Isaacs, N.W., Vijayan, M.
Deposit date:1989-07-10
Release date:1990-04-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:The structure of 2Zn pig insulin crystals at 1.5 A resolution.
Philos.Trans.R.Soc.London,Ser.B, 319, 1988
2INS
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THE STRUCTURE OF DES-PHE B1 BOVINE INSULIN
Descriptor:DES-PHE B1 INSULIN (CHAIN A), DES-PHE B1 INSULIN (CHAIN B), ZINC ION
Authors:Smith, G.D., Duax, W.L., Dodson, E.J., Dodson, G.G., Degraaf, R.A.G., Reynolds, C.D.
Deposit date:1982-05-10
Release date:1982-08-05
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The Structure of Des-Phe B1 Bovine Insulin
Acta Crystallogr.,Sect.B, 38, 1982
1ZNI
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INSULIN
Descriptor:INSULIN, ZINC ION, CHLORIDE ION
Authors:Turkenburg, M.G.W., Whittingham, J.L., Dodson, G.G., Dodson, E.J., Xiao, B., Bentley, G.A.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2018-07-04
Method:X-RAY DIFFRACTION (1.498 Å)
Cite:Structure of insulin in 4-zinc insulin.
Nature, 261, 1976
3JSD
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INSULIN'S BIOSYNTHESIS AND ACTIVITY HAVE OPPOSING STRUCTURAL REQUIREMENTS: A NEW FACTOR IN NEONATAL DIABETES MELLITUS
Descriptor:Insulin A chain, Insulin B chain, ZINC ION, ...
Authors:Weiss, M.A., Wan, Z.L., Dodson, E.J., Liu, M., Xu, B., Hua, Q.X., Turkenburg, M., Whittingham, J., Nakagawa, S.H., Huang, K., Hu, S.Q., Jia, W.H., Wang, S.H., Brange, J., Whittaker, J., Arvan, P., Katsoyannis, P.G., Dodson, G.G.
Deposit date:2009-09-10
Release date:2010-09-15
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
1ZNJ
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INSULIN, MONOCLINIC CRYSTAL FORM
Descriptor:INSULIN, PHENOL, ZINC ION, ...
Authors:Turkenburg, M.G.W., Whittingham, J.L., Turkenburg, J.P., Dodson, G.G., Derewenda, U., Smith, G.D., Dodson, E.J., Derewenda, Z.S., Xiao, B.
Deposit date:1997-09-23
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure Determination and Refinement of Two Crystal Forms of Native Insulins
To be Published
3TGL
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STRUCTURE AND MOLECULAR MODEL REFINEMENT OF RHIZOMUCOR MIEHEI TRIACYLGLYCERIDE LIPASE: A CASE STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT
Descriptor:TRIACYL-GLYCEROL ACYLHYDROLASE
Authors:Brady, L., Brzozowski, A.M., Derewenda, Z.S., Dodson, E.J., Dodson, G.G., Tolley, S.P., Turkenburg, J.P., Christiansen, L., Huge-Jensen, B., Norskov, L., Thim, L.
Deposit date:1991-07-29
Release date:1993-07-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:STRUCTURE AND MOLECULAR-MODEL REFINEMENT OF RHIZOMUCOR-MIEHEI TRIACYLGLYCERIDE LIPASE - A CASE-STUDY OF THE USE OF SIMULATED ANNEALING IN PARTIAL MODEL REFINEMENT.
Acta Crystallogr.,Sect.B, 48, 1992
1MPJ
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X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL
Descriptor:PHENOL INSULIN, PHENOL, ZINC ION, ...
Authors:Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G.
Deposit date:1995-09-13
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
2TCI
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X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL
Descriptor:THIOCYANATE INSULIN, THIOCYANATE ION, ZINC ION
Authors:Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G.
Deposit date:1995-09-13
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
3MTH
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X-RAY CRYSTALLOGRAPHIC STUDIES ON HEXAMERIC INSULINS IN THE PRESENCE OF HELIX-STABILIZING AGENTS, THIOCYANATE, METHYLPARABEN AND PHENOL
Descriptor:METHYLPARABEN INSULIN, 4-HYDROXY-BENZOIC ACID METHYL ESTER, ZINC ION, ...
Authors:Whittingham, J.L., Dodson, E.J., Moody, P.C.E., Dodson, G.G.
Deposit date:1995-09-13
Release date:1996-01-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray crystallographic studies on hexameric insulins in the presence of helix-stabilizing agents, thiocyanate, methylparaben, and phenol.
Biochemistry, 34, 1995
3ROV
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INSULIN'S BIOSYNTHESIS AND ACTIVITY HAVE OPPOSING STRUCTURAL REQUIREMENTS: A NEW FACTOR IN NEONATAL DIABETES MELLITUS
Descriptor:Insulin, PHENOL, ZINC ION, ...
Authors:Weiss, M.A., Wan, Z.L., Dodson, E.J., Liu, M., Xu, B., Hua, Q.X., Turkenburg, M., Whittingham, J., Nakagawa, S.H., Huang, K., Hu, S.Q., Jia, W.H., Wang, S.H., Brange, J., Whittaker, J., Arvan, P., Katsoyannis, P.G., Dodson, G.G.
Deposit date:2011-04-26
Release date:2012-05-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insulin's biosynthesis and activity have opposing structural requirements: a new factor in neonatal diabetes mellitus
To be Published
1GQM
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THE STRUCTURE OF S100A12 IN A HEXAMERIC FORM AND ITS PROPOSED ROLE IN RECEPTOR SIGNALLING
Descriptor:CALGRANULIN C, CALCIUM ION
Authors:Moroz, O.V., Antson, A.A., Dodson, E.G., Burrel, H.J., Grist, S.J., Lloyd, R.M., Maitland, N.J., Dodson, G.G., Wilson, K.S., Lukanidin, E., Bronstein, I.B.
Deposit date:2001-11-26
Release date:2002-02-28
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:The Structure of S100A12 in a Hexameric Form and its Proposed Role in Receptor Signalling
Acta Crystallogr.,Sect.D, 58, 2002
1QAW
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REGULATORY FEATURES OF THE TRP OPERON AND THE CRYSTAL STRUCTURE OF THE TRP RNA-BINDING ATTENUATION PROTEIN FROM BACILLUS STEAROTHERMOPHILUS.
Descriptor:TRP RNA-BINDING ATTENUATION PROTEIN, TRYPTOPHAN
Authors:Chen, X.-P., Antson, A.A., Yang, M., Baumann, C., Dodson, E.J., Dodson, G.G., Gollnick, P.
Deposit date:1999-03-31
Release date:1999-04-16
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Regulatory features of the trp operon and the crystal structure of the trp RNA-binding attenuation protein from Bacillus stearothermophilus.
J.Mol.Biol., 289, 1999
2Z71
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STRUCTURE OF TRUNCATED MUTANT CYS1GLY OF PENICILLIN V ACYLASE FROM BACILLUS SPHAERICUS CO-CRYSTALLIZED WITH PENICILLIN V
Descriptor:Penicillin acylase, (2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID
Authors:Pathak, M.C., Brannigan, J., Dodson, G.G., Suresh, C.G.
Deposit date:2007-08-10
Release date:2008-08-26
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Studies on the catalysis and post translational processing of penicillin V acylase
To be published
3P2X
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INSULIN FIBRILLATION IS THE JANUS FACE OF INDUCED FIT. A CHIARAL CLAMP STABILIZES THE NATIVE STATE AT THE EXPENSE OF ACTIVITY
Descriptor:Insulin, ZINC ION, CHLORIDE ION, ...
Authors:Hua, Q.X., Wan, Z.L., Huang, K., Hu, S.Q., Phillip, N.F., Jia, W.H., Whittingham, J., Dodson, G.G., Katsoyannis, P.G., Weiss, M.A.
Deposit date:2010-10-04
Release date:2011-11-23
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (2 Å)
Cite:Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
3P33
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INSULIN FIBRILLATION IS THE JANUS FACE OF INDUCED FIT. A CHIRAL CLAMP STABILIZES THE NATIVE STATE AT THE EXPENSE OF ACTIVITY
Descriptor:Insulin, PHENOL, ZINC ION, ...
Authors:Hua, Q.X., Wan, Z.L., Huang, K., Hu, S.Q., Phillip, N.F., Jia, W.H., Whittingham, J., Dodson, G.G., Katsoyannis, P.G., Weiss, M.A.
Deposit date:2010-10-04
Release date:2011-11-23
Last modified:2014-10-15
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Insulin fibrillation is the Janus face of induced fit. A chiral clamp stabilizes the native state at the expense of activity
To be Published
6INS
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X-RAY ANALYSIS OF THE SINGLE CHAIN B29-A1 PEPTIDE-LINKED INSULIN MOLECULE. A COMPLETELY INACTIVE ANALOGUE
Descriptor:INSULIN, ZINC ION
Authors:Derewenda, U., Derewenda, Z., Dodson, E.J., Dodson, G.G., Bing, X., Markussen, J.
Deposit date:1992-11-25
Release date:1994-01-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:X-ray analysis of the single chain B29-A1 peptide-linked insulin molecule. A completely inactive analogue.
J.Mol.Biol., 220, 1991
1AX4
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TRYPTOPHANASE FROM PROTEUS VULGARIS
Descriptor:TRYPTOPHANASE, POTASSIUM ION
Authors:Isupov, M.N., Antson, A.A., Dodson, E.J., Dodson, G.G., Dementieva, I.S., Zakomirdina, L.N., Wilson, K.S., Dauter, Z., Lebedev, A.A., Harutyunyan, E.H.
Deposit date:1997-10-28
Release date:1998-01-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystal structure of tryptophanase.
J.Mol.Biol., 276, 1998
1IZA
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
1IZB
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ROLE OF B13 GLU IN INSULIN ASSEMBLY: THE HEXAMER STRUCTURE OF RECOMBINANT MUTANT (B13 GLU-> GLN) INSULIN
Descriptor:INSULIN, ZINC ION
Authors:Xiao, B., Dodson, G.G.
Deposit date:1992-10-16
Release date:1993-10-31
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Role of B13 Glu in insulin assembly. The hexamer structure of recombinant mutant (B13 Glu-->Gln) insulin.
J.Mol.Biol., 228, 1992
1GKF
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CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM
Descriptor:PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ...
Authors:McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A.
Deposit date:2001-08-13
Release date:2002-01-04
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.41 Å)
Cite:Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
1GM7
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CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM
Descriptor:PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ...
Authors:McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A.
Deposit date:2001-09-11
Release date:2001-11-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
1GM8
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CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM
Descriptor:PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, CALCIUM ION, ...
Authors:McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A.
Deposit date:2001-09-11
Release date:2001-11-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
1GM9
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CRYSTAL STRUCTURES OF PENICILLIN ACYLASE ENZYME-SUBSTRATE COMPLEXES: STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM
Descriptor:PENICILLIN G ACYLASE ALPHA SUBUNIT, PENICILLIN G ACYLASE BETA SUBUNIT, 1,2-ETHANEDIOL, ...
Authors:McVey, C.E., Walsh, M.A., Dodson, G.G., Wilson, K.S., Brannigan, J.A.
Deposit date:2001-09-12
Release date:2001-11-28
Last modified:2019-07-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structures of Penicillin Acylase Enzyme- Substrate Complexes: Structural Insights Into the Catalytic Mechanism
J.Mol.Biol., 313, 2001
1PMB
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THE DETERMINATION OF THE CRYSTAL STRUCTURE OF RECOMBINANT PIG MYOGLOBIN BY MOLECULAR REPLACEMENT AND ITS REFINEMENT
Descriptor:MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE
Authors:Smerdon, S.J., Oldfield, T.J., Dodson, E.J., Dodson, G.G., Hubbard, R.E., Wilkinson, A.J.
Deposit date:1989-11-27
Release date:1990-01-15
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Determination of the crystal structure of recombinant pig myoglobin by molecular replacement and its refinement.
Acta Crystallogr.,Sect.B, 46, 1990
1GZR
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HUMAN INSULIN-LIKE GROWTH FACTOR; ESRF DATA
Descriptor:INSULIN-LIKE GROWTH FACTOR I, N-DODECYL-N,N-DIMETHYL-3-AMMONIO-1-PROPANESULFONATE
Authors:Brzozowski, A.M., Dodson, E.J., Dodson, G.G., Murshudov, G., Verma, C., Turkenburg, J.P., De Bree, F.M., Dauter, Z.
Deposit date:2002-05-28
Release date:2002-07-25
Last modified:2019-05-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural Origins of the Functional Divergence of Human Insulin-Like Growth Factor-I and Insulin
Biochemistry, 41, 2002