5TGL

A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX

Summary for 5TGL

DescriptorLIPASE, N-HEXYLPHOSPHONATE ETHYL ESTER (2 entities in total)
Functional Keywordshydrolase(carboxylic esterase)
Biological sourceRhizomucor miehei (Mucor miehei)
Total number of polymer chains1
Total molecular weight29718.16
Authors
Brzozowski, A.M.,Derewenda, U.,Derewenda, Z.S.,Dodson, G.G.,Lawson, D.,Turkenburg, J.P.,Bjorkling, F.,Huge-Jensen, B.,Patkar, S.R.,Thim, L. (deposition date: 1991-10-30, release date: 1994-01-31, Last modification date: 2011-07-13)
Primary citation
Brzozowski, A.M.,Derewenda, U.,Derewenda, Z.S.,Dodson, G.G.,Lawson, D.M.,Turkenburg, J.P.,Bjorkling, F.,Huge-Jensen, B.,Patkar, S.A.,Thim, L.
A model for interfacial activation in lipases from the structure of a fungal lipase-inhibitor complex.
Nature, 351:491-494, 1991
PubMed: 2046751 (PDB entries with the same primary citation)
DOI: 10.1038/351491a0
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3 Å)
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Structure validation

ClashscoreSidechain outliers340MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution