5TGL

A MODEL FOR INTERFACIAL ACTIVATION IN LIPASES FROM THE STRUCTURE OF A FUNGAL LIPASE-INHIBITOR COMPLEX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006629	biological_process	lipid metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE HEE A 270

Chain	Residue
A	SER82
A	SER144
A	PHE251
A	HIS257

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site_id	CAT
Number of Residues	3
Details	CATALYTIC SITE

Chain	Residue
A	SER144
A	ASP203
A	HIS257

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Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. VAVTGHSLGG

Chain	Residue	Details
A	VAL138-GLY147

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000305|PubMed:2304552

Chain	Residue	Details
A	SER144

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: Charge relay system => ECO:0000305|PubMed:2304552

Chain	Residue	Details
A	ASP203
A	HIS257

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site_id	SWS_FT_FI3
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ASP256

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