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6B0T
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STRUCTURAL INSIGHTS INTO THE INDUCED-FIT INHIBITION OF FASCIN BY A SMALL MOLECULE
Descriptor:Fascin, 4-methyl-N-(1-{[4-(trifluoromethyl)phenyl]methyl}-1H-indazol-3-yl)-1,2-oxazole-5-carboxamide
Authors:Dey, R., Huang, X.Y.
Deposit date:2017-09-15
Release date:2018-04-18
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor.
J. Mol. Biol., 430, 2018
4HC7
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CRYSTAL STRUCTURE OF THE FULL DNA BINDING DOMAIN OF GATA3-COMPLEX 2
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2017-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HC9
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 3
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*TP*TP*CP*CP*TP*AP*AP*AP*TP*CP*AP*GP*AP*GP*AP*TP*AP*AP*CP*C)-3'), DNA (5'-D(*AP*AP*GP*GP*TP*TP*AP*TP*CP*TP*CP*TP*GP*AP*TP*TP*TP*AP*GP*G)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2014-12-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
4HCA
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DNA BINDING BY GATA TRANSCRIPTION FACTOR-COMPLEX 1
Descriptor:Trans-acting T-cell-specific transcription factor GATA-3, DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*AP*TP*CP*TP*GP*AP*TP*AP*AP*GP*AP*CP*G)-3'), DNA (5'-D(*TP*TP*CP*GP*TP*CP*TP*TP*AP*TP*CP*AP*GP*AP*TP*GP*GP*AP*CP*A)-3'), ...
Authors:Chen, Y., Bates, D.L., Dey, R., Chen, L.
Deposit date:2012-09-28
Release date:2012-12-05
Last modified:2013-01-02
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:DNA Binding by GATA Transcription Factor Suggests Mechanisms of DNA Looping and Long-Range Gene Regulation.
Cell Rep, 2, 2012
2FP1
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SECRETED CHORISMATE MUTASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Chorismate mutase, LEAD (II) ION
Authors:Okvist, M., Dey, R., Sasso, S., Grahn, E., Kast, P., Krengel, U.
Deposit date:2006-01-15
Release date:2006-03-28
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed
J.Mol.Biol., 357, 2006
2FP2
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SECRETED CHORISMATE MUTASE FROM MYCOBACTERIUM TUBERCULOSIS
Descriptor:Chorismate mutase, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID
Authors:Okvist, M., Dey, R., Sasso, S., Grahn, E., Kast, P., Krengel, U.
Deposit date:2006-01-15
Release date:2006-03-28
Last modified:2018-03-07
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:1.6A Crystal Structure of the Secreted Chorismate Mutase from Mycobacterium tuberculosis: Novel Fold Topology Revealed
J.Mol.Biol., 357, 2006
3KMD
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CRYSTAL STRUCTURE OF THE P53 CORE DOMAIN BOUND TO A FULL CONSENSUS SITE AS A SELF-ASSEMBLED TETRAMER
Descriptor:Cellular tumor antigen p53, 5'-D(*GP*GP*GP*CP*AP*TP*GP*CP*CP*TP*AP*GP*GP*CP*AP*TP*GP*CP*C)-3', ZINC ION
Authors:Chen, Y., Dey, R., Chen, L.
Deposit date:2009-11-10
Release date:2010-02-23
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystal structure of the p53 core domain bound to a full consensus site as a self-assembled tetramer.
Structure, 18, 2010
3KOV
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STRUCTURE OF MEF2A BOUND TO DNA REVEALS A COMPLETELY FOLDED MADS-BOX/MEF2 DOMAIN THAT RECOGNIZES DNA AND RECRUITS TRANSCRIPTION CO-FACTORS
Descriptor:Myocyte-specific enhancer factor 2A, DNA (5'-D(*AP*AP*CP*TP*AP*TP*TP*TP*AP*TP*AP*AP*G)-3'), DNA (5'-D(*TP*CP*TP*TP*AP*TP*AP*AP*AP*TP*AP*GP*T)-3')
Authors:Wu, Y., Dey, R., Han, A., Jayathilaka, N., Philips, M., Ye, J., Chen, L.
Deposit date:2009-11-14
Release date:2010-02-16
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structure of the MADS-box/MEF2 Domain of MEF2A Bound to DNA and Its Implication for Myocardin Recruitment.
J.Mol.Biol., 397, 2010
3MU6
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INHIBITING THE BINDING OF CLASS IIA HISTONE DEACETYLASES TO MYOCYTE ENHANCER FACTOR-2 BY SMALL MOLECULES
Descriptor:Myocyte-specific enhancer factor 2A, DNA (5'-D(*AP*AP*AP*GP*CP*TP*AP*TP*TP*AP*TP*TP*AP*GP*CP*TP*T)-3'), DNA (5'-D(*TP*AP*AP*GP*CP*TP*AP*AP*TP*AP*AP*TP*AP*GP*CP*TP*T)-3'), ...
Authors:Jayathilaka, N., Han, A., Gaffney, K., Dey, R., He, J., Ye, J., Gao, T., Petasis, N.A., Chen, L.
Deposit date:2010-05-01
Release date:2011-11-02
Last modified:2017-11-08
Method:X-RAY DIFFRACTION (2.434 Å)
Cite:Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2.
Nucleic Acids Res., 40, 2012