Author results

2OM7
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STRUCTURAL BASIS FOR INTERACTION OF THE RIBOSOME WITH THE SWITCH REGIONS OF GTP-BOUND ELONGATION FACTORS
分子名称:Fragment of 16S rRNA (h14), Fragment of 16S rRNA (h15), Fragment of 16S rRNA (h44), ...
著者Connell, S.R., Wilson, D.N., Rost, M., Schueler, M., Giesebrecht, J., Dabrowski, M., Mielke, T., Fucini, P., Spahn, C.M.T.
登録日2007-01-21
公開日2008-01-15
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors.
Mol.Cell, 25, 2007
3DEG
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COMPLEX OF ELONGATING ESCHERICHIA COLI 70S RIBOSOME AND EF4(LEPA)-GMPPNP
分子名称:A/L-tRNA, P-tRNA, 30S RNA helix 8, ...
著者Connell, S.R., Topf, M., Qin, Y., Wilson, D.N., Mielke, T., Fucini, P., Nierhaus, K.H., Spahn, C.M.T.
登録日2008-06-10
公開日2008-08-19
最終更新日2014-04-16
実験手法ELECTRON MICROSCOPY (10.9 Å)
主引用文献A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
Nat.Struct.Mol.Biol., 15, 2008
2NOQ
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STRUCTURE OF RIBOSOME-BOUND CRICKET PARALYSIS VIRUS IRES RNA
分子名称:CrPV IRES, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Schuler, M., Connell, S.R., Lescoute, A., Giesebrecht, J., Dabrowski, M., Schroeer, B., Mielke, T., Penczek, P.A., Westhof, E., Spahn, C.M.T.
登録日2006-10-26
公開日2006-11-21
最終更新日2012-02-15
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structure of the ribosome-bound cricket paralysis virus IRES RNA.
Nat.Struct.Mol.Biol., 13, 2006
2ZJP
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THIOPEPTIDE ANTIBIOTIC NOSIHEPTIDE BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
分子名称:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
著者Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
登録日2008-03-07
公開日2008-06-17
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
2ZJQ
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INTERACTION OF L7 WITH L11 INDUCED BY MICROCCOCIN BINDING TO THE DEINOCOCCUS RADIODURANS 50S SUBUNIT
分子名称:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
著者Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
登録日2008-03-08
公開日2008-06-17
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
2ZJR
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REFINED NATIVE STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT (50S) FROM DEINOCOCCUS RADIODURANS
分子名称:ribosomal 23S RNA, ribosomal 5S RNA, 50S ribosomal protein L2, ...
著者Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
登録日2008-03-08
公開日2008-06-17
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin.
Mol.Cell, 30, 2008
3CF5
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THIOPEPTIDE ANTIBIOTIC THIOSTREPTON BOUND TO THE LARGE RIBOSOMAL SUBUNIT OF DEINOCOCCUS RADIODURANS
分子名称:50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ...
著者Harms, J.M., Wilson, D.N., Schluenzen, F., Connell, S.R., Stachelhaus, T., Zaborowska, Z., Spahn, C.M.T., Fucini, P.
登録日2008-03-02
公開日2008-06-17
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30, 2008
3DLL
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THE OXAZOLIDINONE ANTIBIOTICS PERTURB THE RIBOSOMAL PEPTIDYL-TRANSFERASE CENTER AND EFFECT TRNA POSITIONING
分子名称:rRNA-23S ribosomal RNA, rRNA-5S ribosomal RNA, 50S ribosomal protein L2, ...
著者Wilson, D.N., Schluenzen, F., Harms, J.M., Starosta, A.L., Connell, S.R., Fucini, P.
登録日2008-06-27
公開日2008-09-16
最終更新日2015-07-22
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
Proc.Natl.Acad.Sci.Usa, 105, 2008
4V5M
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TRNA TRANLOCATION ON THE 70S RIBOSOME: THE PRE-TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(PRE)
分子名称:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
登録日2010-10-01
公開日2014-07-09
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.8 Å)
主引用文献Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V5N
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TRNA TRANSLOCATION ON THE 70S RIBOSOME: THE POST- TRANSLOCATIONAL TRANSLOCATION INTERMEDIATE TI(POST)
分子名称:16S RRNA, 30S RIBOSOMAL PROTEIN S2, 30S RIBOSOMAL PROTEIN S3, ...
著者Ratje, A.H., Loerke, J., Mikolajka, A., Bruenner, M., Hildebrand, P.W., Starosta, A.L., Doenhoefer, A., Connell, S.R., Fucini, P., Mielke, T., Whitford, P.C., Onuchic, J.N., Yu, Y., Sanbonmatsu, K.Y., Hartmann, R.K., Penczek, P.A., Wilson, D.N., Spahn, C.M.T.
登録日2010-10-21
公開日2014-07-09
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Head Swivel on the Ribosome Facilitates Translocation by Means of Intra-Subunit tRNA Hybrid Sites.
Nature, 468, 2010
4V8V
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STRUCTURE AND CONFORMATIONAL VARIABILITY OF THE MYCOBACTERIUM TUBERCULOSIS FATTY ACID SYNTHASE MULTIENZYME COMPLEX
分子名称:TYPE-I FATTY ACID SYNTHASE, FLAVIN MONONUCLEOTIDE
著者Ciccarelli, L., Connell, S.R., Enderle, M., Mills, D.J., Vonck, J., Grininger, M.
登録日2013-04-18
公開日2014-07-09
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4V8W
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STRUCTURE AND CONFORMATIONAL VARIABILITY OF THE MYCOBACTERIUM TUBERCULOSIS FATTY ACID SYNTHASE MULTIENZYME COMPLEX
分子名称:TYPE-I FATTY ACID SYNTHASE, FLAVIN MONONUCLEOTIDE
著者Ciccarelli, L., Connell, S.R., Enderle, M., Mills, D.J., Vonck, J., Grininger, M.
登録日2013-04-18
公開日2014-07-09
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (17.5 Å)
主引用文献Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21, 2013
4YHH
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH TIGECYCLINE
分子名称:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
著者Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Dhimole, N., Zhou, S., Lopez-Alonso, J.P., Connell, S.R., Fucini, P.
登録日2015-02-27
公開日2015-04-08
最終更新日2016-02-03
実験手法X-RAY DIFFRACTION (3.417 Å)
主引用文献Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Antimicrob.Agents Chemother., 59, 2015
5DM6
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS
分子名称:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
著者Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
登録日2015-09-08
公開日2015-11-11
最終更新日2016-02-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5DM7
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CRYSTAL STRUCTURE OF THE 50S RIBOSOMAL SUBUNIT FROM DEINOCOCCUS RADIODURANS IN COMPLEX WITH HYGROMYCIN A
分子名称:50S ribosomal protein L1, 50S ribosomal protein L2, 50S ribosomal protein L3, ...
著者Kaminishi, T., Schedlbauer, A., Ochoa-Lizarralde, B., Connell, S.R., Fucini, P.
登録日2015-09-08
公開日2015-11-11
最終更新日2015-11-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.
Nucleic Acids Res., 43, 2015
5IWA
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CRYSTAL STRUCTURE OF THE 30S RIBOSOMAL SUBUNIT FROM THERMUS THERMOPHILUS IN COMPLEX WITH THE GE81112 PEPTIDE ANTIBIOTIC
分子名称:30S ribosomal protein S2, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
著者Schedlbauer, A., Kaminishi, T., Ochoa-Lizarralde, B., Chieko, N., Masahito, K., Takemoto, C., Yokoyama, S., Connell, S.R., Fucini, P.
登録日2016-03-22
公開日2016-04-27
最終更新日2017-04-05
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding.
Proc.Natl.Acad.Sci.USA, 113, 2016
5NO2
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE)
分子名称:16S ribosomal RNA, 30S ribosomal protein S4, 30S ribosomal protein S5, ...
著者Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
登録日2017-04-10
公開日2017-05-24
最終更新日2017-09-13
実験手法ELECTRON MICROSCOPY (5.16 Å)
主引用文献RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO3
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE WITHOUT US3)
分子名称:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
著者Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
登録日2017-04-10
公開日2017-05-31
最終更新日2017-09-13
実験手法ELECTRON MICROSCOPY (5.16 Å)
主引用文献RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5NO4
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RSGA-GDPNP BOUND TO THE 30S RIBOSOMAL SUBUNIT (RSGA ASSEMBLY INTERMEDIATE WITH US3)
分子名称:16S ribosomal RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
著者Lopez-Alonso, J.P., Kaminishi, T., Kikuchi, T., Hirata, Y., Iturrioz, I., Dhimole, N., Schedlbauer, A., Hase, Y., Goto, S., Kurita, D., Muto, A., Zhou, S., Naoe, C., Mills, D.J., Gil-Carton, D., Takemoto, C., Himeno, H., Fucini, P., Connell, S.R.
登録日2017-04-10
公開日2017-05-31
最終更新日2017-09-13
実験手法ELECTRON MICROSCOPY (5.16 Å)
主引用文献RsgA couples the maturation state of the 30S ribosomal decoding center to activation of its GTPase pocket.
Nucleic Acids Res., 45, 2017
5ME0
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STRUCTURE OF THE 30S PRE-INITIATION COMPLEX 1 (30S IC-1) STALLED BY GE81112
分子名称:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
著者Lopez-Alonso, J.P., Fabbretti, A., Kaminishi, T., Iturrioz, I., Brandi, L., Gil Carton, D., Gualerzi, C., Fucini, P., Connell, S.
登録日2016-11-14
公開日2017-01-11
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
5ME1
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STRUCTURE OF THE 30S PRE-INITIATION COMPLEX 2 (30S IC-2) STALLED BY GE81112
分子名称:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
著者Lopez-Alonso, J.P., Fabbretti, A., Kaminishi, T., Iturrioz, I., Brandi, L., Gil Carton, D., Gualerzi, C., Fucini, P., Connell, S.
登録日2016-11-14
公開日2017-01-11
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (13.5 Å)
主引用文献Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways.
Nucleic Acids Res., 45, 2017
4V68
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T. THERMOPHILUS 70S RIBOSOME IN COMPLEX WITH MRNA, TRNAS AND EF-TU.GDP.KIRROMYCIN TERNARY COMPLEX, FITTED TO A 6.4 A CRYO-EM MAP.
分子名称:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S4, ...
著者Schuette, J.-C., Spahn, C.M.T.
登録日2008-12-11
公開日2014-07-09
最終更新日2015-03-25
実験手法ELECTRON MICROSCOPY (6.4 Å)
主引用文献GTPase activation of elongation factor EF-Tu by the ribosome during decoding
Embo J., 28, 2009