2ZJP

Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans

Summary for 2ZJP

Related1D8T 1E9W 1OLN 2C77 2JQ7 3CF5 2ZJQ 2ZJR
Related PRD IDPRD_000221
Descriptor50S RIBOSOMAL PROTEIN L33, 50S RIBOSOMAL PROTEIN L34, 50S RIBOSOMAL PROTEIN L35, ... (34 entities in total)
Functional Keywordsnosiheptide, thiopeptide, thiazole, antibiotic, l11, s50, antibacterial, ribosome-antibiotic complex, ribosome, zinc-finger, translation regulation, rna-binding, ribosome/antibiotic
Biological sourceDEINOCOCCUS RADIODURANS
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Total number of polymer chains31
Total molecular weight1366820.62
Authors
Harms, J.M.,Wilson, D.N.,Schluenzen, F.,Connell, S.R.,Stachelhaus, T.,Zaborowska, Z.,Spahn, C.M.T.,Fucini, P. (deposition date: 2008-03-07, release date: 2008-06-17, Last modification date: 2012-12-12)
Primary citation
Harms, J.M.,Wilson, D.N.,Schluenzen, F.,Connell, S.R.,Stachelhaus, T.,Zaborowska, Z.,Spahn, C.M.,Fucini, P.
Translational Regulation Via L11: Molecular Switches on the Ribosome Turned on and Off by Thiostrepton and Micrococcin.
Mol.Cell, 30:26-, 2008
PubMed: 18406324 (PDB entries with the same primary citation)
DOI: 10.1016/J.MOLCEL.2008.01.009
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (3.7 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone6415.0%8.5%5.8%0.49MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2zjp
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Molmil generated image of 2zjp
rotated about x axis by 90°
Molmil generated image of 2zjp
rotated about y axis by 90°