2C77
EF-Tu complexed with a GTP analog and the antibiotic GE2270 A
Summary for 2C77
Entry DOI | 10.2210/pdb2c77/pdb |
Related | 1D8T 1E9W 1OLN 2C78 2JQ7 2ZJP 3CF5 |
Related PRD ID | PRD_000225 |
Descriptor | ELONGATION FACTOR TU-B, THIOCILLIN GE2270, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... (6 entities in total) |
Functional Keywords | hydrolase-antibiotic complex, thiopeptide, antibiotic, antibacterial, thiazole, oxazole, hydrolase, gtpase, translation elongation factor, protein synthesis, nucleotide-binding, phosphorylation, hydrolase/antibiotic |
Biological source | THERMUS THERMOPHILUS More |
Total number of polymer chains | 2 |
Total formula weight | 46863.19 |
Authors | Parmeggiani, A.,Krab, I.M.,Okamura, S.,Nielsen, R.C.,Nyborg, J.,Nissen, P. (deposition date: 2005-11-18, release date: 2006-03-16, Last modification date: 2023-12-13) |
Primary citation | Parmeggiani, A.,Krab, I.M.,Okamura, S.,Nielsen, R.C.,Nyborg, J.,Nissen, P. Structural basis of the action of pulvomycin and GE2270 A on elongation factor Tu. Biochemistry, 45:6846-6857, 2006 Cited by PubMed: 16734421DOI: 10.1021/bi0525122 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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