2ZJP

Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	1	50S RIBOSOMAL PROTEIN L33	polymer	55	6374.5	1	UniProt (Q9RSS4) Pfam (PF00471) In PDB	DEINOCOCCUS RADIODURANS
2	2	50S RIBOSOMAL PROTEIN L34	polymer	47	5626.6	1	UniProt (Q9RSH2) Pfam (PF00468) In PDB	DEINOCOCCUS RADIODURANS
3	3	50S RIBOSOMAL PROTEIN L35	polymer	66	7448.1	1	UniProt (Q9RSW6) Pfam (PF01632) In PDB	DEINOCOCCUS RADIODURANS
4	4	50S RIBOSOMAL PROTEIN L36	polymer	37	4322.3	1	UniProt (Q9RSK0) Pfam (PF00444) In PDB	DEINOCOCCUS RADIODURANS
5	5	NOSIHEPTIDE	polymer	13	1195.3	1	UniProt (C6FX52) In PDB BIRD (PRD_000221)	STREPTOMYCES ACTUOSUS
6	A	50S RIBOSOMAL PROTEIN L2	polymer	274	29976.6	1	UniProt (Q9RXJ9) Pfam (PF00181) Pfam (PF03947) In PDB	DEINOCOCCUS RADIODURANS
7	B	50S RIBOSOMAL PROTEIN L3	polymer	211	22477.2	1	UniProt (Q9RXK2) Pfam (PF00297) In PDB	DEINOCOCCUS RADIODURANS
8	C	50S RIBOSOMAL PROTEIN L4	polymer	205	22308.2	1	UniProt (Q9RXK1) Pfam (PF00573) In PDB	DEINOCOCCUS RADIODURANS
9	D	50S RIBOSOMAL PROTEIN L5	polymer	180	20379.9	1	UniProt (Q9RXJ0) Pfam (PF00673) Pfam (PF00281) In PDB	DEINOCOCCUS RADIODURANS
10	E	50S RIBOSOMAL PROTEIN L6	polymer	185	19613.6	1	UniProt (Q9RSL3) Pfam (PF00347) In PDB	DEINOCOCCUS RADIODURANS
11	F	50S RIBOSOMAL PROTEIN L11	polymer	144	14889.2	1	UniProt (Q9RSS7) Pfam (PF03946) Pfam (PF00298) In PDB	DEINOCOCCUS RADIODURANS
12	G	50S RIBOSOMAL PROTEIN L13	polymer	174	19223.2	1	UniProt (Q9RXY1) Pfam (PF00572) In PDB	DEINOCOCCUS RADIODURANS
13	H	50S RIBOSOMAL PROTEIN L14	polymer	134	14256.5	1	UniProt (Q9RXJ2) Pfam (PF00238) In PDB	DEINOCOCCUS RADIODURANS
14	I	50S RIBOSOMAL PROTEIN L15	polymer	156	16894.2	1	UniProt (Q9RSK9) Pfam (PF00828) In PDB	DEINOCOCCUS RADIODURANS
15	J	50S RIBOSOMAL PROTEIN L16	polymer	142	16257.2	1	UniProt (Q9RXJ5) Pfam (PF00252) In PDB	DEINOCOCCUS RADIODURANS
16	K	50S RIBOSOMAL PROTEIN L17	polymer	116	12926.1	1	UniProt (Q9RSJ5) Pfam (PF01196) In PDB	DEINOCOCCUS RADIODURANS
17	L	50S RIBOSOMAL PROTEIN L18	polymer	114	12163.9	1	UniProt (Q9RSL2) Pfam (PF00861) In PDB	DEINOCOCCUS RADIODURANS
18	M	50S RIBOSOMAL PROTEIN L19	polymer	166	18347.8	1	UniProt (Q9RWB4) Pfam (PF01245) In PDB	DEINOCOCCUS RADIODURANS
19	N	50S RIBOSOMAL PROTEIN L20	polymer	118	13991.3	1	UniProt (Q9RSW7) Pfam (PF00453) In PDB	DEINOCOCCUS RADIODURANS
20	O	50S RIBOSOMAL PROTEIN L21	polymer	100	11165.7	1	UniProt (Q9RY64) Pfam (PF00829) In PDB	DEINOCOCCUS RADIODURANS
21	P	50S RIBOSOMAL PROTEIN L22	polymer	134	15190.9	1	UniProt (Q9RXJ7) Pfam (PF00237) In PDB	DEINOCOCCUS RADIODURANS
22	Q	50S RIBOSOMAL PROTEIN L23	polymer	95	10539.2	1	UniProt (Q9RXK0) Pfam (PF00276) In PDB	DEINOCOCCUS RADIODURANS
23	R	50S RIBOSOMAL PROTEIN L24	polymer	115	12384.4	1	UniProt (Q9RXJ1) Pfam (PF00467) Pfam (PF17136) In PDB	DEINOCOCCUS RADIODURANS
24	S	50S RIBOSOMAL PROTEIN L25	polymer	237	25415.4	1	UniProt (Q9RX88) Pfam (PF01386) Pfam (PF14693) In PDB	DEINOCOCCUS RADIODURANS	GENERAL STRESS PROTEIN CTC
25	T	50S RIBOSOMAL PROTEIN L27	polymer	91	9609.1	1	UniProt (Q9RY65) Pfam (PF01016) In PDB	DEINOCOCCUS RADIODURANS
26	U	50S RIBOSOMAL PROTEIN L28	polymer	81	8982.6	1	UniProt (Q9RRG8) Pfam (PF00830) In PDB	DEINOCOCCUS RADIODURANS
27	V	50S RIBOSOMAL PROTEIN L29	polymer	67	7775.0	1	UniProt (Q9RXJ4) Pfam (PF00831) In PDB	DEINOCOCCUS RADIODURANS
28	W	50S RIBOSOMAL PROTEIN L30	polymer	55	6079.2	1	UniProt (Q9RSL0) Pfam (PF00327) In PDB	DEINOCOCCUS RADIODURANS
29	X	RIBOSOMAL 23S RNA	polymer	2880	933405.0	1	GenBank (AE000513)	DEINOCOCCUS RADIODURANS
30	Y	50S RIBOSOMAL PROTEIN L32	polymer	60	6810.0	1	UniProt (P49228) Pfam (PF01783) In PDB	DEINOCOCCUS RADIODURANS
31	Z	RIBOSOMAL 5S RNA	polymer	123	39605.7	1	GenBank (AE000513)	DEINOCOCCUS RADIODURANS
32	4, Y	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
33	5	4-(hydroxymethyl)-3-methyl-1H-indole-2-carboxylic acid	non-polymer		205.2	1	BIRD (PRD_000221) Chemie (NO1)
34	X, M, Z	MAGNESIUM ION	non-polymer		24.3	35	Chemie (MG)

Sequence modifications

J: 2 - 142 (UniProt: Q9RXJ5)

PDB	External Database	Details
Met 1	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	31
	Total formula weight	1365633.9
Non-Polymers*	Number of molecules	38
	Total formula weight	1186.7
All*	Total formula weight	1366820.6

*Water molecules are not included.