4V8W

Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex

This is a large structure.

Summary for 4V8W

Related4BJD 4BJE
Integrates4BJF 4BJG
EMDB information2357
DescriptorTYPE-I FATTY ACID SYNTHASE, FLAVIN MONONUCLEOTIDE (2 entities in total)
Functional Keywordshydrolase, fatty acid synthesis, sample heterogeneity, protein flexibility, codimensional principal component analysis
Biological sourceMYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains6
Total molecular weight1982065.88
Authors
Ciccarelli, L.,Connell, S.R.,Enderle, M.,Mills, D.J.,Vonck, J.,Grininger, M. (deposition date: 2013-04-18, release date: 2014-07-09, Last modification date: 2017-08-02)
Primary citation
Ciccarelli, L.,Connell, S.R.,Enderle, M.,Mills, D.J.,Vonck, J.,Grininger, M.
Structure and Conformational Variability of the Mycobacterium Tuberculosis Fatty Acid Synthase Multienzyme Complex.
Structure, 21:1251-, 2013
PubMed: 23746808 (PDB entries with the same primary citation)
DOI: 10.1016/J.STR.2013.04.023
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY (17.5 Å)
?

Structure validation

ClashscoreRamachandran outliersSidechain outliers200.7%4.9%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 4v8w
no rotation
Molmil generated image of 4v8w
rotated about x axis by 90°
Molmil generated image of 4v8w
rotated about y axis by 90°