4V8W

Structure and conformational variability of the Mycobacterium tuberculosis fatty acid synthase multienzyme complex

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004312	molecular_function	fatty acid synthase activity
A	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
A	0005835	cellular_component	fatty acid synthase complex
A	0006633	biological_process	fatty acid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
B	0004312	molecular_function	fatty acid synthase activity
B	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
B	0005835	cellular_component	fatty acid synthase complex
B	0006633	biological_process	fatty acid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
C	0004312	molecular_function	fatty acid synthase activity
C	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C	0005835	cellular_component	fatty acid synthase complex
C	0006633	biological_process	fatty acid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
D	0004312	molecular_function	fatty acid synthase activity
D	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
D	0005835	cellular_component	fatty acid synthase complex
D	0006633	biological_process	fatty acid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
E	0004312	molecular_function	fatty acid synthase activity
E	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
E	0005835	cellular_component	fatty acid synthase complex
E	0006633	biological_process	fatty acid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
F	0004312	molecular_function	fatty acid synthase activity
F	0004318	molecular_function	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F	0005835	cellular_component	fatty acid synthase complex
F	0006633	biological_process	fatty acid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue FMN D 4000

Chain	Residue
D	ALA433
D	GLU577
D	ALA581
D	GLY582
D	GLY613
D	GLY614
D	GLY646
D	THR647
D	ILE892
D	ALA897
D	GLY434
D	MET435
D	THR436
D	PRO437
D	ASN488
D	LEU490
D	SER523
D	LYS550

---

site_id	AC2
Number of Residues	18
Details	binding site for residue FMN E 4000

Chain	Residue
E	ALA433
E	GLY434
E	MET435
E	THR436
E	PRO437
E	ASN488
E	LEU490
E	SER523
E	LYS550
E	GLU577
E	ALA581
E	GLY582
E	GLY613
E	GLY614
E	GLY646
E	THR647
E	ILE892
E	ALA897

---

site_id	AC3
Number of Residues	18
Details	binding site for residue FMN F 4000

Chain	Residue
F	ALA433
F	GLY434
F	MET435
F	THR436
F	PRO437
F	ASN488
F	LEU490
F	SER523
F	LYS550
F	GLU577
F	ALA581
F	GLY582
F	GLY613
F	GLY614
F	GLY646
F	THR647
F	ILE892
F	ALA897

---

site_id	AC4
Number of Residues	18
Details	binding site for residue FMN A 4000

Chain	Residue
A	ALA433
A	GLY434
A	MET435
A	THR436
A	PRO437
A	ASN488
A	LEU490
A	SER523
A	LYS550
A	GLU577
A	ALA581
A	GLY582
A	GLY613
A	GLY614
A	GLY646
A	THR647
A	ILE892
A	ALA897

---

site_id	AC5
Number of Residues	18
Details	binding site for residue FMN B 4000

Chain	Residue
B	ALA433
B	GLY434
B	MET435
B	THR436
B	PRO437
B	ASN488
B	LEU490
B	SER523
B	LYS550
B	GLU577
B	ALA581
B	GLY582
B	GLY613
B	GLY614
B	GLY646
B	THR647
B	ILE892
B	ALA897

---

site_id	AC6
Number of Residues	18
Details	binding site for residue FMN C 4000

Chain	Residue
C	GLU577
C	ALA581
C	GLY582
C	GLY613
C	GLY614
C	GLY646
C	THR647
C	ILE892
C	ALA897
C	ALA433
C	GLY434
C	MET435
C	THR436
C	PRO437
C	ASN488
C	LEU490
C	SER523
C	LYS550

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