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294D
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INTERCALATED CYTOSINE MOTIF AND NOVEL ADENINE CLUSTERS IN THE CRYSTAL STRUCTURE OF TETRAHYMENA TELOMERE
分子名称:DNA (5'-D(*AP*AP*CP*CP*CP*C)-3')
著者Cai, L., Chen, L., Raghavan, S., Ratliff, R., Moyzis, R., Rich, A.
登録日1996-10-30
公開日1998-10-19
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere.
Nucleic Acids Res., 26, 1998
190D
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CRYSTAL STRUCTURE OF A FOUR-STRANDED INTERCALATED DNA: D(C4)
分子名称:DNA (5'-D(*CP*CP*CP*C)-3')
著者Chen, L., Cai, L., Zhang, X., Rich, A.
登録日1994-09-02
公開日1995-02-07
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a four-stranded intercalated DNA: d(C4).
Biochemistry, 33, 1994
1JPY
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CRYSTAL STRUCTURE OF IL-17F
分子名称:interleukin 17F, 2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE, N-ACETYL-D-GLUCOSAMINE, ...
著者Hymowitz, S.G., Filvaroff, E.H., Yin, J., Lee, J., Cai, L., Risser, P., Maruoka, M., Mao, W., Foster, J., Kelley, R., Pan, G., Gurney, A.L., de Vos, A.M., Starovasnik, M.A.
登録日2001-08-03
公開日2001-09-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding.
EMBO J., 20, 2001
2M0O
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THE SOLUTION STRUCTURE OF HUMAN PHF1 IN COMPLEX WITH H3K36ME3
分子名称:PHD finger protein 1, H3K36me3 peptide
著者Song, J., Patel, D.J.
登録日2012-10-30
公開日2013-01-16
最終更新日2013-02-27
実験手法SOLUTION NMR
主引用文献An H3K36 Methylation-Engaging Tudor Motif of Polycomb-like Proteins Mediates PRC2 Complex Targeting.
Mol.Cell, 49, 2013
2RBE
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THE DISCOVERY OF 2-ANILINOTHIAZOLONES AS 11BETA-HSD1 INHIBITORS
分子名称:Corticosteroid 11-beta-dehydrogenase isozyme 1, (5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Zhang, J., Jordan, S.R., Li, V.
登録日2007-09-18
公開日2008-01-15
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitors.
Bioorg.Med.Chem.Lett., 17, 2007
5TBP
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CRYSTAL STRUCTURE OF RXR-ALPHA LIGAND BINDING DOMAIN COMPLEXED WITH SYNTHETIC MODULATOR K8003
分子名称:Retinoic acid receptor RXR-alpha, [(1Z)-5-fluoro-2-methyl-1-{[4-(propan-2-yl)phenyl]methylidene}-1H-inden-3-yl]acetic acid, ACETATE ION, ...
著者Aleshin, A.E., Liddington, R.C., Su, Y., Zhang, X.
登録日2016-09-12
公開日2017-08-09
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Modulation of nongenomic activation of PI3K signalling by tetramerization of N-terminally-cleaved RXR alpha.
Nat Commun, 8, 2017
6MX8
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CRYSTAL STRUCTURE OF ANAPLASTIC LYMPHOMA KINASE (ALK) BOUND BY BRIGATINIB
分子名称:ALK tyrosine kinase receptor, 5-chloro-N~4~-[2-(dimethylphosphoryl)phenyl]-N~2~-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}pyrimidine-2,4-diamine
著者Dougan, D.R., Zhou, T.
登録日2018-10-30
公開日2018-12-12
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase.
J. Med. Chem., 59, 2016