5W88
 
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5WCL
 | | NMR structure of the N-domain of troponin C bound to switch region of troponin I and 3-methyldiphenylamine (solvent exposed mode) | | Descriptor: | 3-methyl-N-phenylaniline, Troponin C, slow skeletal and cardiac muscles,Troponin I, ... | | Authors: | Cai, F, Hwang, P.M, Sykes, B.D. | | Deposit date: | 2017-06-30 | | Release date: | 2017-07-19 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
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6MV3
 | | NMR structure of the cNTnC-cTnI chimera bound to calcium desensitizer W7 | | Descriptor: | CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE, Troponin C, ... | | Authors: | Cai, F, Hwang, P.M, Sykes, B.D. | | Deposit date: | 2018-10-24 | | Release date: | 2018-11-14 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin.
Biochemistry, 57, 2018
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7UH9
 | | NMR structure of the cNTnC-cTnI chimera bound to W8 | | Descriptor: | CALCIUM ION, N-(7-aminoheptyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ... | | Authors: | Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D. | | Deposit date: | 2022-03-26 | | Release date: | 2022-06-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
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5VLN
 | | NMR structure of the N-domain of troponin C bound to switch region of troponin I | | Descriptor: | Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle | | Authors: | Cai, F, Hwang, P.M, Sykes, B.D. | | Deposit date: | 2017-04-25 | | Release date: | 2017-05-24 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Structures reveal details of small molecule binding to cardiac troponin.
J. Mol. Cell. Cardiol., 101, 2016
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4HT5
 | | CO2 concentrating mechanism protein P, CcmP form 1 | | Descriptor: | CO2 concentrating mechanism protein P | | Authors: | Cai, F, Sutter, M, Kerfeld, C.A. | | Deposit date: | 2012-10-31 | | Release date: | 2013-04-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.51 Å) | | Cite: | The structure of CcmP, a tandem bacterial microcompartment domain protein from the beta-carboxysome, forms a subcompartment within a microcompartment.
J.Biol.Chem., 288, 2013
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4HT7
 | | CO2 concentrating mechanism protein P, CcmP form 2 | | Descriptor: | CO2 concentrating mechanism protein P | | Authors: | Cai, F, Sutter, M, Kerfeld, C.A. | | Deposit date: | 2012-10-31 | | Release date: | 2013-04-17 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.301 Å) | | Cite: | The structure of CcmP, a tandem bacterial microcompartment domain protein from the beta-carboxysome, forms a subcompartment within a microcompartment.
J.Biol.Chem., 288, 2013
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7JGI
 | | NMR structure of the cNTnC-cTnI chimera bound to A7 | | Descriptor: | 7-{[(5-chloronaphthalen-1-yl)sulfonyl]amino}heptanoic acid, CALCIUM ION, Troponin C, ... | | Authors: | Cai, F, Robertson, I.M, Kampourakis, T, Klein, B.A, Sykes, B.D. | | Deposit date: | 2020-07-19 | | Release date: | 2020-09-02 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | The Role of Electrostatics in the Mechanism of Cardiac Thin Filament Based Sensitizers.
Acs Chem.Biol., 15, 2020
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7UHA
 | | NMR structure of the cNTnC-cTnI chimera bound to W6 | | Descriptor: | CALCIUM ION, N-(5-aminopentyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ... | | Authors: | Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D. | | Deposit date: | 2022-03-26 | | Release date: | 2022-06-15 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
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4OX7
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4OX8
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4OX6
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6U6O
 | | Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH846 | | Descriptor: | DH846 Fab heavy chain, DH846 Fab light chain | | Authors: | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | | Deposit date: | 2019-08-30 | | Release date: | 2021-03-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.806 Å) | | Cite: | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
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6U6M
 | | Crystal structure of a vaccine-elicited anti-HIV-1 rhesus macaque antibody DH840.1 | | Descriptor: | DH840.1 Fab heavy chain, DH840.1 Fab light chain | | Authors: | Chen, W.-H, Choe, M, Saunders, K.O, Joyce, M.G. | | Deposit date: | 2019-08-30 | | Release date: | 2021-03-24 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.683 Å) | | Cite: | Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates.
Plos Pathog., 17, 2021
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6P3B
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7LAB
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7LAA
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7LD1
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7LCN
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8G8D
 | | Crystal structure of DH1346 Fab in complex with HIV proximal MPER peptide | | Descriptor: | DH1346 heavy chain, DH1346 light chain, FLUORIDE ION, ... | | Authors: | Niyongabo, A, Janus, B.M, Ofek, G. | | Deposit date: | 2023-02-17 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.02 Å) | | Cite: | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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8G8A
 | | Crystal structure of DH1317.8 Fab in complex with HIV proximal MPER peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1317.8 heavy chain, DH1317.8 light chain, ... | | Authors: | Janus, B.M, Astavans, A, Ofek, G. | | Deposit date: | 2023-02-17 | | Release date: | 2024-05-22 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.44 Å) | | Cite: | Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans.
Cell, 187, 2024
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5NPL
 | | Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria, Yb-derivative at 2.8 A resolution | | Descriptor: | 10-((2R)-2-HYDROXYPROPYL)-1,4,7,10-TETRAAZACYCLODODECANE 1,4,7-TRIACETIC ACID, Similar to tr|Q8YYT1|Q8YYT1, YTTERBIUM (III) ION | | Authors: | Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S. | | Deposit date: | 2017-04-17 | | Release date: | 2018-05-30 | | Last modified: | 2018-07-11 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4JAN
 | | crystal structure of broadly neutralizing antibody CH103 in complex with HIV-1 gp120 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIGEN BINDING FRAGMENT OF HEAVY CHAIN of CH103, ANTIGEN BINDING FRAGMENT OF LIGHT CHAIN of CH103, ... | | Authors: | Zhou, T, Moquin, S, Zheng, A, Srivatsan, S, Kwong, P.D. | | Deposit date: | 2013-02-18 | | Release date: | 2013-04-03 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Nature, 496, 2013
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5NMU
 | | Structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria | | Descriptor: | CBS-CP12, CHLORIDE ION | | Authors: | Hackenberg, C, Hakanpaa, J, Antonyuk, S.V, Dittmann, E, Lamzin, V.S. | | Deposit date: | 2017-04-07 | | Release date: | 2018-05-16 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5NVD
 | | Crystal structure of hexameric CBS-CP12 protein from bloom-forming cyanobacteria at 2.5 A resolution in P6322 crystal form | | Descriptor: | CBS-CP12 | | Authors: | Hackenberg, C, Hakanpaa, J, Eigner, C, Antonyuk, S.V, Dittmann, E, Lamzin, V.S. | | Deposit date: | 2017-05-04 | | Release date: | 2018-05-30 | | Last modified: | 2024-01-17 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural and functional insights into the unique CBS-CP12 fusion protein family in cyanobacteria.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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