6MV3
NMR structure of the cNTnC-cTnI chimera bound to calcium desensitizer W7
Summary for 6MV3
| Entry DOI | 10.2210/pdb6mv3/pdb |
| NMR Information | BMRB: 30529 |
| Descriptor | Troponin C, slow skeletal and cardiac muscles,Troponin I, cardiac muscle chimera, CALCIUM ION, N-(6-AMINOHEXYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE (3 entities in total) |
| Functional Keywords | cardiac troponin, calcium binding protein, ef hand, metal binding protein, calcium desensitizer, w7 |
| Biological source | Homo sapiens (Human) More |
| Total number of polymer chains | 1 |
| Total formula weight | 14567.07 |
| Authors | Cai, F.,Hwang, P.M.,Sykes, B.D. (deposition date: 2018-10-24, release date: 2018-11-14, Last modification date: 2023-06-14) |
| Primary citation | Cai, F.,Hwang, P.M.,Sykes, B.D. Structural Changes Induced by the Binding of the Calcium Desensitizer W7 to Cardiac Troponin. Biochemistry, 57:6461-6469, 2018 Cited by PubMed: 30376637DOI: 10.1021/acs.biochem.8b00882 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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