5W88

NMR structure of the N-domain of troponin C bound to switch region of troponin I and 3-methyldiphenylamine (peptide mode)

Summary for 5W88

• Entry DOI: 10.2210/pdb5w88/pdb
• NMR Information: BMRB: 30308
• Descriptor: Troponin C, Troponin I, 3-methyl-N-phenylaniline (2 entities in total)
• Functional Keywords: cardiac troponin, calcium binding protein, ef hand, metal binding protein, calcium sensitizer
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 13678.64

Authors

Cai, F.,Hwang, P.M.,Sykes, B.D. (deposition date: 2017-06-21, release date: 2017-07-12, Last modification date: 2024-05-15)

• Primary citation: Cai, F.,Li, M.X.,Pineda-Sanabria, S.E.,Gelozia, S.,Lindert, S.,West, F.,Sykes, B.D.,Hwang, P.M.; Structures reveal details of small molecule binding to cardiac troponin.; J. Mol. Cell. Cardiol., 101:134-144, 2016; PubMed: 27825981; DOI: 10.1016/j.yjmcc.2016.10.016

Experimental method

SOLUTION NMR