Author results

3Q0K
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CRYSTAL STRUCTURE OF HUMAN PACSIN 2 F-BAR
Descriptor:Protein kinase C and casein kinase substrate in neurons protein 2
Authors:Bai, X., Meng, G., Zheng, X.
Deposit date:2010-12-15
Release date:2012-02-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of human PACSIN 2 F-BAR domain
To be Published
3SYV
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CRYSTAL STRUCTURE OF MPACSIN 3 F-BAR DOMAIN MUTANT
Descriptor:Protein kinase C and casein kinase II substrate protein 3
Authors:Bai, X.
Deposit date:2011-07-18
Release date:2012-05-16
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
J.Biol.Chem., 287, 2012
2OT5
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CRYSTAL STRUCTURE OF THE HIV GP41 CORE WITH THE ENFUVIRTIDE RESISTANCE MUTATION N43D
Descriptor:HIV-1 gp41 glycoprotein
Authors:Bai, X., Seedorff, J.E., Green, J., Dwyer, J.J.
Deposit date:2007-02-07
Release date:2008-06-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
3Q84
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CRYSTAL STRUCTURE OF HUMAN PACSIN 1 F-BAR DOMAIN
Descriptor:Protein kinase C and casein kinase substrate in neurons protein 1
Authors:Bai, X.
Deposit date:2011-01-06
Release date:2012-02-22
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human PACSIN 1 F-BAR domain
To be Published
5A63
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CRYO-EM STRUCTURE OF THE HUMAN GAMMA-SECRETASE COMPLEX AT 3.4 ANGSTROM RESOLUTION.
Descriptor:NICASTRIN, PRESENILIN-1 (E.C.3.4.23.-), GAMMA-SECRETASE SUBUNIT APH-1A, GAMMA-SECRETASE SUBUNIT PEN-2
Authors:Bai, X., Yan, C., Yang, G., Lu, P., Ma, D., Sun, L., Zhou, R., Scheres, S.H.W., Shi, Y.
Deposit date:2015-06-24
Release date:2015-08-05
Last modified:2016-12-28
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:An Atomic Structure of Human Gamma-Secretase
Nature, 525, 2015
3QE6
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MOUSE PACSIN 3 F-BAR DOMAIN STRUCTURE
Descriptor:Protein kinase C and casein kinase II substrate protein 3
Authors:Meng, G., Bai, X., Zheng, X.
Deposit date:2011-01-19
Release date:2012-01-25
Last modified:2013-07-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Rigidity of wedge loop in PACSIN 3 protein is a key factor in dictating diameters of tubules
J.Biol.Chem., 287, 2012
3QNI
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CRYSTAL STRUCTURE OF HUMAN PACSIN 1 F-BAR DOMAIN
Descriptor:Protein kinase C and casein kinase substrate in neurons protein 1
Authors:Meng, G., Bai, X., Zheng, X.
Deposit date:2011-02-08
Release date:2011-08-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal structure of human PACSIN 1 F-BAR domain
to be published
4AYD
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STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 1 R106A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-20
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules
Plos Pathog., 8, 2012
4AYE
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STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 1 E283AE304A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-20
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYI
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STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 3 WILD TYPE
Descriptor:COMPLEMENT FACTOR H, LIPOPROTEIN GNA1870 CCOMPND 7
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.31 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYM
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STRUCTURE OF A COMPLEX BETWEEN CCPS 6 AND 7 OF HUMAN COMPLEMENT FACTOR H AND NEISSERIA MENINGITIDIS FHBP VARIANT 3 P106A MUTANT
Descriptor:COMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4AYN
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STRUCTURE OF THE C-TERMINAL BARREL OF NEISSERIA MENINGITIDIS FHBP VARIANT 2
Descriptor:FACTOR H-BINDING PROTEIN
Authors:Johnson, S., Tan, L., van der Veen, S., Caesar, J., Goicoechea De Jorge, E., Everett, R.J., Bai, X., Exley, R.M., Ward, P.N., Ruivo, N., Trivedi, K., Cumber, E., Jones, R., Newham, L., Staunton, D., Borrow, R., Pickering, M., Lea, S.M., Tang, C.M.
Deposit date:2012-06-21
Release date:2012-11-07
Last modified:2015-03-25
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8, 2012
4V91
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:Ribosome
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V92
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KLUYVEROMYCES LACTIS 80S RIBOSOME IN COMPLEX WITH CRPV-IRES
Descriptor:Ribosome
Authors:Fernandez, I.S., Bai, X., Scheres, S.H.W., Ramakrishnan, V.
Deposit date:2014-03-21
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
Cell(Cambridge,Mass.), 157, 2014
4V5X
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THE CRYO-EM STRUCTURE OF A 3D DNA-ORIGAMI OBJECT
Descriptor:DNA-origami object
Authors:Bai, X.C., Martin, T.G., Scheres, S.H.W., Dietz, H.
Deposit date:2012-10-09
Release date:2014-07-09
Last modified:2014-12-10
Method:ELECTRON MICROSCOPY (11.5 Å)
Cite:Cryo-Em Structure of a 3D DNA-Origami Object.
Proc.Natl.Acad.Sci.USA, 109, 2012
3CP1
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STRUCTURE OF A LONGER THERMALSTABLE CORE DOMAIN OF HIV-1 GP41 CONTAINING THE ENFUVIRTIDE RESISTANCE MUTATION N43D
Descriptor:Envelope glycoprotein
Authors:Wang, Z.M., Dwyer, J.J.
Deposit date:2008-03-30
Release date:2008-06-17
Last modified:2010-04-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
3CYO
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STRUCTURE OF A LONGER THERMALSTABLE CORE DOMAIN OF HIV-1 GP41 CONTAINING THE ENFUVIRTIDE RESISTANCE MUTATION N43D AND COMPLEMENTARY MUTATION E137K
Descriptor:Transmembrane protein
Authors:Wang, Z.M., Dwyer, J.J.
Deposit date:2008-04-25
Release date:2008-06-17
Last modified:2010-04-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure.
Biochemistry, 47, 2008
3J8H
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STRUCTURE OF THE RABBIT RYANODINE RECEPTOR RYR1 IN COMPLEX WITH FKBP12 AT 3.8 ANGSTROM RESOLUTION
Descriptor:Ryanodine receptor 1, Peptidyl-prolyl cis-trans isomerase FKBP1A (E.C.5.2.1.8)
Authors:Yan, Z., Bai, X., Yan, C., Wu, J., Scheres, S.H.W., Shi, Y., Yan, N.
Deposit date:2014-10-26
Release date:2014-12-10
Last modified:2015-02-25
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution.
Nature, 517, 2015
3J9K
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STRUCTURE OF DARK APOPTOSOME IN COMPLEX WITH DRONC CARD DOMAIN
Descriptor:Apaf-1 related killer DARK, Caspase Nc (E.C.3.4.22.-)
Authors:Pang, Y., Bai, X., Yan, C., Hao, Q., Chen, Z., Wang, J., Scheres, S.H.W., Shi, Y.
Deposit date:2015-02-04
Release date:2015-02-25
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29, 2015
3J9L
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STRUCTURE OF DARK APOPTOSOME FROM DROSOPHILA MELANOGASTER
Descriptor:Apaf-1 related killer DARK
Authors:Pang, Y., Bai, X., Yan, C., Hao, Q., Chen, Z., Wang, J., Scheres, S.H.W., Shi, Y.
Deposit date:2015-02-04
Release date:2015-02-25
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29, 2015
3JBT
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ATOMIC STRUCTURE OF THE APAF-1 APOPTOSOME
Descriptor:Apoptotic protease-activating factor 1, Cytochrome c
Authors:Zhou, M., Li, Y., Hu, Q., Bai, X., Huang, W., Yan, C., Scheres, S.H.W., Shi, Y.
Deposit date:2015-10-15
Release date:2015-11-18
Last modified:2017-01-18
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1
Genes Dev., 29, 2015
3MX7
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CRYSTAL STRUCTURE ANALYSIS OF HUMAN FAIM-NTD
Descriptor:Fas apoptotic inhibitory molecule 1
Authors:Li, G., Qu, L., Meng, G., Zheng, X.
Deposit date:2010-05-06
Release date:2011-05-18
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:The structure of human Fas apoptotic inhibitory molecule
To be Published
5JSG
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CRYSTAL STRUCTURE OF SPINDLIN1 BOUND TO COMPOUND EML405
Descriptor:Spindlin-1
Authors:Su, X., Li, H.
Deposit date:2016-05-08
Release date:2017-05-10
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Developing Spindlin1 Small Molecule Inhibitors Using Protein Microarrays
Nat.Chem.Biol., 2017
5JSJ
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CRYSTAL STRUCTURE OF SPINDLIN1 BOUND TO COMPOUND EML631
Descriptor:Spindlin-1
Authors:Su, X., Li, H.
Deposit date:2016-05-08
Release date:2017-05-24
Method:X-RAY DIFFRACTION (2.348 Å)
Cite:Envolving Spindlin1 Small Molecular Inhibitors Using Protein Microarrays
Nat.Chem.Biol., 2017
3BXW
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CRYSTAL STRUCTURE OF STABILIN-1 INTERACTING CHITINASE-LIKE PROTEIN, SI-CLP
Descriptor:Chitinase domain-containing protein 1
Authors:Meng, G., Green, T.J.
Deposit date:2008-01-15
Release date:2009-01-20
Last modified:2012-04-11
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of human stabilin-1 interacting chitinase-like protein (SI-CLP) reveals a saccharide-binding cleft with lower sugar-binding selectivity.
J.Biol.Chem., 285, 2010
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