8HGP

The EREG-bound EGFR/HER2 ectodomain complex

Summary for 8HGP

• Entry DOI: 10.2210/pdb8hgp/pdb
• EMDB information: 34745
• Descriptor: Receptor tyrosine-protein kinase erbB-2, Epidermal growth factor receptor, Proepiregulin, ... (6 entities in total)
• Functional Keywords: membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 170418.96

Authors

Zhang, Z.,Bai, X. (deposition date: 2022-11-15, release date: 2023-02-08, Last modification date: 2023-03-01)

• Primary citation: Bai, X.,Sun, P.,Wang, X.,Long, C.,Liao, S.,Dang, S.,Zhuang, S.,Du, Y.,Zhang, X.,Li, N.,He, K.,Zhang, Z.; Structure and dynamics of the EGFR/HER2 heterodimer.; Cell Discov, 9:18-18, 2023; PubMed: 36781849; DOI: 10.1038/s41421-023-00523-5

Experimental method

ELECTRON MICROSCOPY (4.53 Å)