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4AYE

Structure of a complex between CCPs 6 and 7 of Human Complement Factor H and Neisseria meningitidis FHbp Variant 1 E283AE304A mutant

Summary for 4AYE
Entry DOI10.2210/pdb4aye/pdb
Related1FHC 1HAQ 1HCC 1HFH 1HFI 1KOV 2G7I 2JGW 2JGX 2UWN 2V8E 2W80 2W81 2WII 2XQW 2Y7S 4AYD
DescriptorCOMPLEMENT FACTOR H, FACTOR H BINDING PROTEIN, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsimmune system, antigens, bacterial proteins, vaccines
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted: P08603
Total number of polymer chains6
Total formula weight127161.72
Authors
Primary citationJohnson, S.,Tan, L.,Van Der Veen, S.,Caesar, J.,Goicoechea De Jorge, E.,Harding, R.J.,Bai, X.,Exley, R.M.,Ward, P.N.,Ruivo, N.,Trivedi, K.,Cumber, E.,Jones, R.,Newham, L.,Staunton, D.,Ufret-Vincenty, R.,Borrow, R.,Pickering, M.C.,Lea, S.M.,Tang, C.M.
Design and Evaluation of Meningococcal Vaccines Through Structure-Based Modification of Host and Pathogen Molecules.
Plos Pathog., 8:2981-, 2012
Cited by
PubMed: 23133374
DOI: 10.1371/JOURNAL.PPAT.1002981
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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