Author results

6CV9
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CYTOPLASMIC DOMAIN OF MTRPC6
Descriptor:Short transient receptor potential channel 6
Authors:Azumaya, C.M., Sierra-Valdez, F.J., Cordero-Morales, J.F., Nakagawa, T.
Deposit date:2018-03-27
Release date:2018-05-23
Last modified:2019-12-11
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Cryo-EM structure of the cytoplasmic domain of murine transient receptor potential cation channel subfamily C member 6 (TRPC6).
J. Biol. Chem., 293, 2018
6UQK
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CRYO-EM STRUCTURE OF TYPE 3 IP3 RECEPTOR REVEALING PRESENCE OF A SELF-BINDING PEPTIDE
Descriptor:inositol 1,4,5-triphosphate receptor, type 3, ZINC ION
Authors:Azumaya, C.M., Linton, E.A., Risener, C.J., Nakagawa, T., Karakas, E.
Deposit date:2019-10-20
Release date:2020-01-15
Last modified:2020-02-19
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Cryo-EM structure of human type-3 inositol triphosphate receptor reveals the presence of a self-binding peptide that acts as an antagonist.
J.Biol.Chem., 295, 2020
7KKJ
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STRUCTURE OF ANTI-SARS-COV-2 SPIKE NANOBODY MNB6
Descriptor:Synthetic nanobody mNb6, SULFATE ION, CHLORIDE ION
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-25
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKK
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY NB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody Nb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (3.03 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
7KKL
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SARS-COV-2 SPIKE IN COMPLEX WITH NEUTRALIZING NANOBODY MNB6
Descriptor:SARS-CoV-2 spike glycoprotein, Synthetic nanobody mNb6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Schoof, M.S., Faust, B.F., Saunders, R.A., Sangwan, S., Rezelj, V., Hoppe, N., Boone, M., Billesboelle, C.B., Puchades, C., Azumaya, C.M., Kratochvil, H.T., Zimanyi, M., Desphande, I., Liang, J., Dickinson, S., Nguyen, H.C., Chio, C.M., Merz, G.E., Thompson, M.C., Diwanji, D., Schaefer, K., Anand, A.A., Dobzinski, N., Zha, B.S., Simoneau, C.R., Leon, K., White, K.M., Chio, U.S., Gupta, M., Jin, M., Li, F., Liu, Y., Zhang, K., Bulkley, D., Sun, M., Smith, A.M., Rizo, A.N., Moss, F., Brilot, A.F., Pourmal, S., Trenker, R., Pospiech, T., Gupta, S., Barsi-Rhyne, B., Belyy, V., Barile-Hill, A.W., Nock, S., Liu, Y., Krogan, N.J., Ralston, C.Y., Swaney, D.L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Walter, P., Manglik, A., QCRG Structural Biology Consortium
Deposit date:2020-10-27
Release date:2020-11-11
Last modified:2020-11-25
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike.
Science, 2020
6D7L
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CYTOPLASMIC DOMAIN OF TRPC3
Descriptor:Short transient receptor potential channel 3
Authors:Sierra-Valdez, F.J., Azumaya, C.M., Nakagawa, T., Cordero-Morales, J.F.
Deposit date:2018-04-25
Release date:2018-08-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.
J. Biol. Chem., 293, 2018
6DJR
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FULL-LENGTH HUMAN TRPC3 IN GDN
Descriptor:Transient Receptor Potential Cation Channel Subfamily C Member 3
Authors:Sierra-Valdez, F.J., Azumaya, C.M., Nakagawa, T., Cordero-Morales, J.F.
Deposit date:2018-05-26
Release date:2018-08-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.
J. Biol. Chem., 293, 2018
6DJS
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HYBRID MODEL OF TRPC3 IN GDN
Descriptor:Short transient receptor potential channel 3
Authors:Sierra-Valdez, F.J., Azumaya, C.M., Nakagawa, T., Cordero-Morales, J.F.
Deposit date:2018-05-26
Release date:2018-08-29
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structure-function analyses of the ion channel TRPC3 reveal that its cytoplasmic domain allosterically modulates channel gating.
J. Biol. Chem., 293, 2018
6W4S
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STRUCTURE OF APO HUMAN FERROPORTIN IN LIPID NANODISC
Descriptor:Solute carrier family 40 member 1, Fab45D8 Heavy Chain, Fab45D8 Light Chain
Authors:Billesboelle, C.B., Azumaya, C.M., Gonen, S., Powers, A., Kretsch, R.C., Schneider, S., Arvedson, T., Dror, R.O., Cheng, Y., Manglik, A.
Deposit date:2020-03-11
Release date:2020-09-09
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
6W4V
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STRUCTURE OF ANTI-FERROPORTIN FAB45D8
Descriptor:Fab45D8 Light Chain, Fab45D8 Heavy Chain, 1,2-ETHANEDIOL
Authors:Billesboelle, C.B., Azumaya, C.M., Gonen, S., Powers, A., Kretsch, R.C., Schneider, S., Arvedson, T., Dror, R.O., Cheng, Y., Manglik, A.
Deposit date:2020-03-11
Release date:2020-09-09
Last modified:2020-11-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
6WBV
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STRUCTURE OF HUMAN FERROPORTIN BOUND TO HEPCIDIN AND COBALT IN LIPID NANODISC
Descriptor:Hepcidin, Solute carrier family 40 member 1, Fab45D8 Light Chain, ...
Authors:Billesboelle, C.B., Azumaya, C.M., Gonen, S., Powers, A., Kretsch, R.C., Schneider, S., Arvedson, T., Dror, R.O., Cheng, Y., Manglik, A.
Deposit date:2020-03-27
Release date:2020-09-09
Last modified:2020-11-11
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structure of hepcidin-bound ferroportin reveals iron homeostatic mechanisms.
Nature, 586, 2020
7KDT
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HUMAN TOM70 IN COMPLEX WITH SARS COV2 ORF9B
Descriptor:Mitochondrial import receptor subunit TOM70, ORF9b protein
Authors:QCRG Structural Biology Consortium
Deposit date:2020-10-09
Release date:2020-10-21
Last modified:2020-11-04
Method:ELECTRON MICROSCOPY (3.05 Å)
Cite:Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.
Science, 2020
4R1Z
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ZEBRA FISH CYTOCHROME P450 17A1 WITH ABIRATERONE
Descriptor:Cyp17a1 protein, PROTOPORPHYRIN IX CONTAINING FE, Abiraterone
Authors:Pallan, P.S., Egli, M.
Deposit date:2014-08-08
Release date:2014-12-31
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
4R20
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ZEBRA FISH CYTOCHROME P450 17A2 WITH ABIRATERONE
Descriptor:Cytochrome P450 family 17 polypeptide 2, PROTOPORPHYRIN IX CONTAINING FE, Abiraterone, ...
Authors:Pallan, P.S., Egli, M.
Deposit date:2014-08-08
Release date:2014-12-31
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.86 Å)
Cite:Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
4R21
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ZEBRA FISH CYTOCHROME P450 17A2 WITH PROGESTERONE
Descriptor:Cytochrome P450 family 17 polypeptide 2, PROTOPORPHYRIN IX CONTAINING FE, PROGESTERONE
Authors:Pallan, P.S., Egli, M.
Deposit date:2014-08-08
Release date:2014-12-31
Last modified:2015-03-04
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural and Kinetic Basis of Steroid 17 alpha, 20-Lyase Activity in Teleost Fish Cytochrome P450 17A1 and Its Absence in Cytochrome P450 17A2.
J.Biol.Chem., 290, 2015
171588
PDB entries from 2020-11-25