9O04

CryoEM structure of the FBXO42-CCDC6-PP2Ac degradasome

Summary for 9O04

• Entry DOI: 10.2210/pdb9o04/pdb
• EMDB information: 49966
• Descriptor: Coiled-coil domain-containing protein 6, F-box only protein 42, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, ... (5 entities in total)
• Functional Keywords: e3 ligase, phosphatase, scaffolding, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 606641.22

Authors

Hsu, P.L.,Michaelian, N.,Azumaya, C.,Coassolo, S.,Yauch, R.L. (deposition date: 2025-04-02, release date: 2026-01-21)

• Primary citation: Hsu, P.L.,Michaelian, N.,Azumaya, C.,Coassolo, S.,Yauch, R.L.,Maculins, T.,Dimitrova, Y.; The SCFFBXO42-CCDC6 axis regulates proteosomal degradation of the catalytic subunit of PP2A; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)