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2UXN
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BU of 2uxn by Molmil
Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation
Descriptor: CHLORIDE ION, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ...
Authors:Yang, M, Culhane, J.C, Szewczuk, L.M, Gocke, C.B, Brautigam, C.A, Tomchick, D.R, Machius, M, Cole, P.A, Yu, H.
Deposit date:2007-03-28
Release date:2007-05-29
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14, 2007
2UXX
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BU of 2uxx by Molmil
Human LSD1 Histone Demethylase-CoREST in complex with an FAD- tranylcypromine adduct
Descriptor: CHLORIDE ION, FAD-trans-2-Phenylcyclopropylamine Adduct, GLYCEROL, ...
Authors:Yang, M, Culhane, J.C, Machius, M, Cole, P.A, Yu, H.
Deposit date:2007-03-30
Release date:2007-08-21
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.74 Å)
Cite:Structural Basis for the Inhibition of the Lsd1 Histone Demethylase by the Antidepressant Trans-2-Phenylcyclopropylamine.
Biochemistry, 46, 2007
6PIK
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BU of 6pik by Molmil
Tetrameric cryo-EM ArnA
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2020-01-15
Method:ELECTRON MICROSCOPY (7.8 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
6PIH
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BU of 6pih by Molmil
Hexameric ArnA cryo-EM structure
Descriptor: Bifunctional polymyxin resistance protein ArnA, UDP-4-amino-4-deoxy-L-arabinose formyltransferase
Authors:Yang, M, Gehring, K.
Deposit date:2019-06-26
Release date:2019-07-31
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (6.6 Å)
Cite:Cryo-electron microscopy structures of ArnA, a key enzyme for polymyxin resistance, revealed unexpected oligomerizations and domain movements.
J.Struct.Biol., 208, 2019
2VFX
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BU of 2vfx by Molmil
Structure of the Symmetric Mad2 Dimer
Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, ...
Authors:Yang, M, Li, B, Liu, C.-J, Tomchick, D.R, Machius, M, Rizo, J, Yu, H, Luo, X.
Deposit date:2007-11-05
Release date:2008-03-18
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Insights Into MAD2 Regulation in the Spindle Checkpoint Revealed by the Crystal Structure of the Symmetric MAD2 Dimer.
Plos Biol., 6, 2008
7YDW
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BU of 7ydw by Molmil
Crystal structure of the MPND-DNA complex
Descriptor: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MPN domain-containing protein
Authors:Yang, M, Chen, Z.
Deposit date:2022-07-04
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.47 Å)
Cite:Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
7YDT
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BU of 7ydt by Molmil
Crystal structure of mouse MPND
Descriptor: MPN domain containing protein
Authors:Yang, M, Chen, Z.
Deposit date:2022-07-04
Release date:2023-02-15
Last modified:2023-03-08
Method:X-RAY DIFFRACTION (2.055 Å)
Cite:Structures of MPND Reveal the Molecular Recognition of Nucleosomes.
Int J Mol Sci, 24, 2023
2H2N
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BU of 2h2n by Molmil
Crystal structure of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
Descriptor: ACETATE ION, CALCIUM ION, Soluble calcium-activated nucleotidase 1
Authors:Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
Deposit date:2006-05-19
Release date:2006-07-18
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2H2U
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BU of 2h2u by Molmil
Crystal structure of the E130Y mutant of human soluble calcium-activated nucleotidase (SCAN) with calcium ion
Descriptor: CALCIUM ION, Soluble calcium-activated nucleotidase 1
Authors:Yang, M, Horii, K, Herr, A.B, Kirley, T.L.
Deposit date:2006-05-19
Release date:2006-07-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Calcium-dependent dimerization of human soluble calcium activated nucleotidase: characterization of the dimer interface.
J.Biol.Chem., 281, 2006
2IW5
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BU of 2iw5 by Molmil
Structural Basis for CoREST-Dependent Demethylation of Nucleosomes by the Human LSD1 Histone Demethylase
Descriptor: AMMONIUM ION, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ...
Authors:Yang, M, Gocke, C.B, Luo, X, Borek, D, Tomchick, D.R, Machius, M, Otwinowski, Z, Yu, H.
Deposit date:2006-06-26
Release date:2006-08-09
Last modified:2019-02-06
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Basis for Corest-Dependent Demethylation of Nucleosomes by the Human Lsd1 Histone Demethylase
Mol.Cell, 23, 2006
4HY6
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BU of 4hy6 by Molmil
Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
Descriptor: 6,6-dimethyl-3-(trifluoromethyl)-1,5,6,7-tetrahydro-4H-indazol-4-one, Heat shock protein HSP 90-alpha
Authors:Yang, M, Li, J, He, J.H.
Deposit date:2012-11-13
Release date:2013-05-15
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.649 Å)
Cite:Crystal Structure of the human Hsp90-alpha N-domain bound to the hsp90 inhibitor FJ1
to be published
4WNB
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BU of 4wnb by Molmil
Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis bound to 3-OPC-CoA
Descriptor: 3-oxo-4-pregnene-20-carboxyl-Coenzyme A, CADMIUM ION, CALCIUM ION, ...
Authors:Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M.
Deposit date:2014-10-11
Release date:2014-10-29
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.76 Å)
Cite:A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
4X28
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BU of 4x28 by Molmil
Crystal structure of the ChsE4-ChsE5 complex from Mycobacterium tuberculosis
Descriptor: Acyl-CoA dehydrogenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE
Authors:Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M.
Deposit date:2014-11-26
Release date:2015-02-18
Last modified:2019-12-18
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
Acs Infect Dis., 1, 2015
4W78
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BU of 4w78 by Molmil
Crystal structure of the ChsH1-ChsH2 complex from Mycobacterium tuberculosis
Descriptor: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Guja, K.E, Yang, M, Sampson, N, Garcia-Diaz, M.
Deposit date:2014-08-21
Release date:2014-10-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.541 Å)
Cite:A Distinct MaoC-like Enoyl-CoA Hydratase Architecture Mediates Cholesterol Catabolism in Mycobacterium tuberculosis.
Acs Chem.Biol., 9, 2014
5I5O
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BU of 5i5o by Molmil
Crystal Structure of N-terminal Domain of Matrix Protein of Thogoto Virus at Neutral pH.
Descriptor: Matrix protein
Authors:Liu, Y, Liang, H, Yang, M.
Deposit date:2016-02-15
Release date:2016-08-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (2.682 Å)
Cite:pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
5I5N
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BU of 5i5n by Molmil
Crystal Structure of N-terminal Domain of Matrix Protein of Thogoto Virus at Acidic pH.
Descriptor: Matrix protein
Authors:Liu, Y, Liang, H, Yang, M.
Deposit date:2016-02-15
Release date:2016-08-17
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.418 Å)
Cite:pH-dependent conformational changes of a Thogoto virus matrix protein reveal mechanisms of viral assembly and uncoating
J.Gen.Virol., 97, 2016
4IKG
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BU of 4ikg by Molmil
Crystal structure of cell death-inducing DFFA-like effector c
Descriptor: Cell death activator CIDE-3, IODIDE ION
Authors:Yang, M, Gao, J.
Deposit date:2012-12-26
Release date:2014-06-04
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9318 Å)
Cite:Perilipin1 promotes unilocular lipid droplet formation through the activation of Fsp27 in adipocytes.
Nat Commun, 4, 2013
4NQJ
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BU of 4nqj by Molmil
Structure of coiled-coil domain
Descriptor: DODECYL-BETA-D-MALTOSIDE, E3 ubiquitin-protein ligase TRIM69
Authors:Yang, M, Li, Y.
Deposit date:2013-11-25
Release date:2014-05-21
Last modified:2022-08-24
Method:X-RAY DIFFRACTION (2.152 Å)
Cite:Structural insights into the TRIM family of ubiquitin E3 ligases.
Cell Res., 24, 2014
3T9N
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BU of 3t9n by Molmil
Crystal structure of a membrane protein
Descriptor: DODECYL-BETA-D-MALTOSIDE, Small-conductance mechanosensitive channel
Authors:Yang, M, Zhang, X, Ge, J, Wang, J.
Deposit date:2011-08-03
Release date:2012-10-31
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.456 Å)
Cite:Structure and molecular mechanism of an anion-selective mechanosensitive channel of small conductance
Proc.Natl.Acad.Sci.USA, 109, 2012
4PSX
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BU of 4psx by Molmil
Crystal structure of histone acetyltransferase complex
Descriptor: COENZYME A, Histone H3, Histone H4, ...
Authors:Yang, M, Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.509 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
4PSW
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BU of 4psw by Molmil
Crystal structure of histone acetyltransferase complex
Descriptor: COENZYME A, Histone H4 type VIII, Histone acetyltransferase type B catalytic subunit, ...
Authors:Yang, M, Li, Y.
Deposit date:2014-03-08
Release date:2014-07-09
Method:X-RAY DIFFRACTION (2.101 Å)
Cite:Hat2p recognizes the histone H3 tail to specify the acetylation of the newly synthesized H3/H4 heterodimer by the Hat1p/Hat2p complex
Genes Dev., 28, 2014
5WY5
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BU of 5wy5 by Molmil
Crystal structure of MAGEG1 and NSE1 complex
Descriptor: MAGNESIUM ION, Melanoma-associated antigen G1, Non-structural maintenance of chromosomes element 1 homolog, ...
Authors:Yang, M, Gao, J.
Deposit date:2017-01-11
Release date:2017-05-03
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.92 Å)
Cite:Mage-Ring Protein Complexes Comprise A Family Of E3 Ubiquitin Ligases.
Mol.Cell, 39, 2010
5YE2
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BU of 5ye2 by Molmil
mammalian endo-lysosomal TRPML1 channel inserting into amphipol
Descriptor: mammalian endo-lysosomal TRPML1 channel
Authors:Yang, M, Gao, N.
Deposit date:2017-09-15
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE1
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BU of 5ye1 by Molmil
structure of endo-lysosomal TRPML1 channel inserting into amphipol: state 2
Descriptor: Mucolipin-1
Authors:Yang, M, Gao, N.
Deposit date:2017-09-15
Release date:2017-12-27
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017
5YE5
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BU of 5ye5 by Molmil
structure of endo-lysosomal TRPML1 channel inserting into nanodisc
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, mammalian endo-lysosomal TRPML1 channel
Authors:Yang, M, Gao, N.
Deposit date:2017-09-15
Release date:2017-11-15
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Cryo-EM structures of the mammalian endo-lysosomal TRPML1 channel elucidate the combined regulation mechanism
Protein Cell, 8, 2017

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