3KCU | | STRUCTURE OF FORMATE CHANNEL | | Descriptor: | Probable formate transporter 1, 2-(6-(2-CYCLOHEXYLETHOXY)-TETRAHYDRO-4,5-DIHYDROXY-2(HYDROXYMETHYL)-2H-PYRAN-3-YLOXY)-TETRAHYDRO-6(HYDROXYMETHYL)-2H-PYRAN-3,4,5-TRIOL | | Authors: | Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-01 | | Last modified: | 2014-01-22 | | Method: | X-RAY DIFFRACTION (2.243 Å) | | Cite: | Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
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3KCV | | STRUCTURE OF FORMATE CHANNEL | | Descriptor: | Probable formate transporter 1 | | Authors: | Wang, Y., Huang, Y., Wang, J., Yan, N., Shi, Y. | | Deposit date: | 2009-10-22 | | Release date: | 2009-12-01 | | Last modified: | 2018-02-21 | | Method: | X-RAY DIFFRACTION (3.198 Å) | | Cite: | Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel
Nature, 462, 2009
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6K3H | |
3GX8 | | STRUCTURAL AND BIOCHEMICAL CHARACTERIZATION OF YEAST MONOTHIOL GLUTAREDOXIN GRX5 | | Descriptor: | Monothiol glutaredoxin-5, mitochondrial, SULFATE ION | | Authors: | Wang, Y., He, Y.X., Yu, J., Xiong, Y., Chen, Y., Zhou, C.Z. | | Deposit date: | 2009-04-01 | | Release date: | 2010-04-14 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.673 Å) | | Cite: | Structural and biochemical characterization of yeast monothiol glutaredoxin Grx5
To be Published
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4ZHQ | |
4ZI7 | |
4ZOL | |
5BMV | | CRYSTAL STRUCTURE OF TUBULIN-STATHMIN-TTL-VINBLASTINE COMPLEX | | Descriptor: | Tubulin alpha-1B chain, Tubulin beta chain, Stathmin-4, ... | | Authors: | Wang, Y., Chen, Q., Zhang, R. | | Deposit date: | 2015-05-23 | | Release date: | 2016-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural Insights into the Pharmacophore of Vinca Domain Inhibitors of Microtubules.
Mol.Pharmacol., 89, 2016
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6J07 | | CRYSTAL STRUCTURE OF HUMAN TERB2 AND TERB1 | | Descriptor: | Telomere repeats-binding bouquet formation protein 2, Telomere repeats-binding bouquet formation protein 1, ZINC ION | | Authors: | Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M. | | Deposit date: | 2018-12-21 | | Release date: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (3.298 Å) | | Cite: | The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
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6J08 | | CRYSTAL STRUCTURE OF HUMAN MAJIN AND TERB2 | | Descriptor: | Membrane-anchored junction protein, Telomere repeats-binding bouquet formation protein 2 | | Authors: | Wang, Y., Chen, Y., Wu, J., Huang, C., Lei, M. | | Deposit date: | 2018-12-21 | | Release date: | 2019-02-27 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | The meiotic TERB1-TERB2-MAJIN complex tethers telomeres to the nuclear envelope.
Nat Commun, 10, 2019
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3TDL | | STRUCTURE OF HUMAN SERUM ALBUMIN IN COMPLEX WITH DAUDA | | Descriptor: | Serum albumin, MYRISTIC ACID, 11-({[5-(dimethylamino)naphthalen-1-yl]sulfonyl}amino)undecanoic acid | | Authors: | Wang, Y., Luo, Z., Shi, X., Wang, H., Nie, L. | | Deposit date: | 2011-08-11 | | Release date: | 2012-06-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin
Protein Sci., 20, 2011
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5EX7 | | CRYSTAL STRUCTURE OF BRAT NHL DOMAIN IN COMPLEX WITH AN 8-NT HUNCHBACK MRNA | | Descriptor: | Brain tumor protein, RNA (5'-R(P*UP*UP*UP*GP*UP*UP*GP*U)-3') | | Authors: | Wang, Y., Yu, Z., Wang, M., Liu, C.P., Yang, N., Xu, R.M. | | Deposit date: | 2015-11-23 | | Release date: | 2015-12-09 | | Last modified: | 2017-10-18 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Crystal structure of Brat NHL domain in complex with an 8-nt hunchback mRNA
To Be Published
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5IJB | | THE LIGAND-FREE STRUCTURE OF THE MOUSE TLR4/MD-2 COMPLEX | | Descriptor: | Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ... | | Authors: | Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B. | | Deposit date: | 2016-03-01 | | Release date: | 2016-04-27 | | Last modified: | 2016-05-04 | | Method: | X-RAY DIFFRACTION (2.91 Å) | | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IJC | | THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/NEOSEPTIN-3 COMPLEX | | Descriptor: | Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ... | | Authors: | Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B. | | Deposit date: | 2016-03-01 | | Release date: | 2016-04-27 | | Last modified: | 2016-05-04 | | Method: | X-RAY DIFFRACTION (2.57 Å) | | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5IJD | | THE CRYSTAL STRUCTURE OF MOUSE TLR4/MD-2/LIPID A COMPLEX | | Descriptor: | Toll-like receptor 4, Variable lymphocyte receptor B chimera, Lymphocyte antigen 96, ... | | Authors: | Wang, Y., Su, L., Morin, M.D., Jones, B.T., Whitby, L.R., Surakattula, M., Huang, H., Shi, H., Choi, J.H., Wang, K., Moresco, E.M., Berger, M., Zhan, X., Zhang, H., Boger, D.L., Beutler, B. | | Deposit date: | 2016-03-01 | | Release date: | 2016-04-27 | | Last modified: | 2016-05-04 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS.
Proc.Natl.Acad.Sci.USA, 113, 2016
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5Y7L | |
3B44 | | CRYSTAL STRUCTURE OF GLPG W136A MUTANT | | Descriptor: | glpG, B-NONYLGLUCOSIDE | | Authors: | Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y. | | Deposit date: | 2007-10-23 | | Release date: | 2008-01-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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3B45 | | CRYSTAL STRUCTURE OF GLPG AT 1.9A RESOLUTION | | Descriptor: | glpG, B-NONYLGLUCOSIDE | | Authors: | Wang, Y., Maegawa, S., Akiyama, Y., Ha, Y. | | Deposit date: | 2007-10-23 | | Release date: | 2008-01-22 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | The role of L1 loop in the mechanism of rhomboid intramembrane protease GlpG.
J.Mol.Biol., 374, 2007
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4XT9 | | RORGAMMA (263-509) COMPLEXED WITH GSK2435341A AND SRC2 | | Descriptor: | Nuclear receptor ROR-gamma, LYS-ILE-LEU-HIS-ARG-LEU-LEU-GLN, N-[4-(2,5-dichlorophenyl)-5-phenyl-1,3-thiazol-2-yl]-2-[4-(ethylsulfonyl)phenyl]acetamide, ... | | Authors: | Wang, Y., Ma, Y. | | Deposit date: | 2015-01-23 | | Release date: | 2015-08-12 | | Last modified: | 2015-09-16 | | Method: | X-RAY DIFFRACTION (2.25 Å) | | Cite: | Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR gamma t inverse agonists
Bioorg.Med.Chem., 23, 2015
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5C8Y | | CRYSTAL STRUCTURE OF T2R-TTL-PLINABULIN COMPLEX | | Descriptor: | Tubulin alpha, Tubulin beta, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-06-26 | | Release date: | 2015-11-04 | | Last modified: | 2016-01-27 | | Method: | X-RAY DIFFRACTION (2.594 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
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5CA0 | | CRYSTAL STRUCTURE OF T2R-TTL-LEXIBULIN COMPLEX | | Descriptor: | Tubulin alpha-1B chain, Uncharacterized protein, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-06-29 | | Release date: | 2015-11-04 | | Last modified: | 2016-01-27 | | Method: | X-RAY DIFFRACTION (2.501 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
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5CA1 | | CRYSTAL STRUCTURE OF T2R-TTL-NOCODAZOLE COMPLEX | | Descriptor: | Tubulin alpha, Tubulin beta-2 chain, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-06-29 | | Release date: | 2015-11-04 | | Last modified: | 2016-01-27 | | Method: | X-RAY DIFFRACTION (2.401 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
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5CB4 | | CRYSTAL STRUCTURE OF T2R-TTL-TIVANTINIB COMPLEX | | Descriptor: | Tubulin alpha, Tubulin beta, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-06-30 | | Release date: | 2015-11-04 | | Last modified: | 2016-01-27 | | Method: | X-RAY DIFFRACTION (2.193 Å) | | Cite: | Structures of a diverse set of colchicine binding site inhibitors in complex with tubulin provide a rationale for drug discovery.
Febs J., 283, 2016
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5EZY | | CRYSTAL STRUCTURE OF T2R-TTL-TACCALONOLIDE AJ COMPLEX | | Descriptor: | Tubulin alpha-1B chain, Tubulin beta-2B chain, Stathmin-4, ... | | Authors: | Wang, Y., Yu, Y., Chen, Q., Yang, J. | | Deposit date: | 2015-11-27 | | Release date: | 2017-01-11 | | Last modified: | 2017-06-21 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Mechanism of microtubule stabilization by taccalonolide AJ
Nat Commun, 8, 2017
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6O58 | | HUMAN MCU-EMRE COMPLEX, DIMER OF CHANNEL | | Descriptor: | Calcium uniporter protein, mitochondrial, Essential MCU regulator, ... | | Authors: | Wang, Y., Bai, X., Jiang, Y. | | Deposit date: | 2019-03-01 | | Release date: | 2019-05-22 | | Last modified: | 2019-05-29 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structural Mechanism of EMRE-Dependent Gating of the Human Mitochondrial Calcium Uniporter.
Cell, 177, 2019
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