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7S4U
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BU of 7s4u by Molmil
Cryo-EM structure of Cas9 in complex with 12-14MM DNA substrate, 5 minute time-point
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, Non-target strand, Target strand, ...
Authors:Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
Deposit date:2021-09-09
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
7S4X
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BU of 7s4x by Molmil
Cas9:gRNA in complex with 18-20MM DNA, 1 minute time-point, kinked active conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, MAGNESIUM ION, NTS, ...
Authors:Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
Deposit date:2021-09-09
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.76 Å)
Cite:Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
7SBB
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BU of 7sbb by Molmil
Structure of type I-D Cascade bound to a ssRNA target
Descriptor: Cas10d, Cas11d, Cas5d, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2021-09-24
Release date:2022-06-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural rearrangements allow nucleic acid discrimination by type I-D Cascade.
Nat Commun, 13, 2022
7SBA
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BU of 7sba by Molmil
Structure of type I-D Cascade bound to a dsDNA target
Descriptor: Cas10d, Cas11d, Cas5d, ...
Authors:Schwartz, E.A, Taylor, D.W.
Deposit date:2021-09-24
Release date:2022-06-08
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural rearrangements allow nucleic acid discrimination by type I-D Cascade.
Nat Commun, 13, 2022
7S9V
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BU of 7s9v by Molmil
DrmAB:ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DrmA, DrmB
Authors:Bravo, J.P.K, Taylor, D.W, Brouns, S.J.J, Aparicio-Maldonado, C.
Deposit date:2021-09-21
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
7S9W
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BU of 7s9w by Molmil
Structure of DrmAB:ADP:DNA complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, DNA (5'-D(P*TP*TP*TP*TP*TP*TP*T)-3'), DrmA, ...
Authors:Bravo, J.P.K, Taylor, D.W, Brounds, S.J.J, Aparicio-Maldonado, C.
Deposit date:2021-09-21
Release date:2022-06-15
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for broad anti-phage immunity by DISARM.
Nat Commun, 13, 2022
9BQV
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BU of 9bqv by Molmil
DdmD dimer apoprotein
Descriptor: Helicase/UvrB N-terminal domain-containing protein
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2024-05-10
Release date:2024-07-03
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Plasmid targeting and destruction by the DdmDE bacterial defence system.
Nature, 630, 2024
7S4V
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BU of 7s4v by Molmil
Cas9 bound to 12-14MM DNA, 60 min time-point, kinked conformation
Descriptor: CRISPR-associated endonuclease Cas9/Csn1, NTS, TS, ...
Authors:Bravo, J.P.K, Taylor, D.W, Liu, M.S, Johnson, K.A.
Deposit date:2021-09-09
Release date:2022-03-02
Last modified:2024-06-05
Method:ELECTRON MICROSCOPY (3.28 Å)
Cite:Structural basis for mismatch surveillance by CRISPR-Cas9.
Nature, 603, 2022
6MDR
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BU of 6mdr by Molmil
Cryo-EM structure of the Ceru+32/GFP-17 protomer
Descriptor: Ceru+32, GFP-17
Authors:Simon, A.J, Zhou, Y, Ramasubramani, V, Glaser, J, Pothukuchy, A, Golihar, J, Gerberich, J.C, Leggere, J.C, Morrow, B.R, Jung, C, Glotzer, S.C, Taylor, D.W, Ellington, A.D.
Deposit date:2018-09-05
Release date:2019-01-23
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (3.47 Å)
Cite:Supercharging enables organized assembly of synthetic biomolecules.
Nat Chem, 11, 2019
6N8K
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BU of 6n8k by Molmil
Cryo-EM structure of early cytoplasmic-immediate (ECI) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
8EW5
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BU of 8ew5 by Molmil
The structure of flightin within myosin thick filaments from Bombus ignitus flight muscle
Descriptor: Flightin
Authors:Li, J, Rahmani, H, Abbasi Yeganeh, F, Rastegarpouyani, H, Taylor, D.W, Wood, N.B, Previs, M.J, Iwamoto, H, Taylor, K.A.
Deposit date:2022-10-21
Release date:2023-01-04
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (6 Å)
Cite:Structure of the Flight Muscle Thick Filament from the Bumble Bee, Bombus ignitus , at 6 angstrom Resolution.
Int J Mol Sci, 24, 2022
8D49
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BU of 8d49 by Molmil
Structure of Cas12a2 binary complex
Descriptor: OrfB_Zn_ribbon domain-containing protein, RNA (26-MER)
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2022-06-01
Release date:2023-01-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8D4A
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BU of 8d4a by Molmil
Cas12a2 quaternary complex
Descriptor: DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*TP*TP*TP*TP*T)-3'), MAGNESIUM ION, ...
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2022-06-01
Release date:2023-01-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.74 Å)
Cite:RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8D4B
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BU of 8d4b by Molmil
Structure of Cas12a2 ternary complex
Descriptor: OrfB_Zn_ribbon domain-containing protein, RNA (28-MER), RNA (41-MER)
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2022-06-01
Release date:2023-01-18
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.92 Å)
Cite:RNA targeting unleashes indiscriminate nuclease activity of CRISPR-Cas12a2.
Nature, 613, 2023
8DFS
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BU of 8dfs by Molmil
type I-C Cascade bound to AcrIF2
Descriptor: Anti-CRISPR protein 30, CRISPR-associated protein, CT1133 family, ...
Authors:O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
Deposit date:2022-06-22
Release date:2023-02-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
8DFO
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BU of 8dfo by Molmil
type I-C Cascade bound to AcrIC4
Descriptor: AcrIC4, CRISPR-associated protein, CT1133 family, ...
Authors:O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
Deposit date:2022-06-22
Release date:2023-02-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
8DFA
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BU of 8dfa by Molmil
type I-C Cascade bound to ssDNA target
Descriptor: CRISPR-associated protein, CT1133 family, TM1801 family, ...
Authors:O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
Deposit date:2022-06-21
Release date:2023-02-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
8DEJ
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BU of 8dej by Molmil
D. vulgaris type I-C Cascade bound to dsDNA target
Descriptor: CRISPR-associated protein, CT1133 family, TM1801 family, ...
Authors:O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
Deposit date:2022-06-20
Release date:2023-02-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.86 Å)
Cite:Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
8DEX
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BU of 8dex by Molmil
type I-C Cascade
Descriptor: CRISPR-associated protein, CT1133 family, TM1801 family, ...
Authors:O'Brien, R.E, Bravo, J.P.K, Ramos, D, Hibshman, G.N, Wright, J.T, Taylor, D.W.
Deposit date:2022-06-21
Release date:2023-02-15
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Structural snapshots of R-loop formation by a type I-C CRISPR Cascade.
Mol.Cell, 83, 2023
7UG6
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BU of 7ug6 by Molmil
Cryo-EM structure of pre-60S ribosomal subunit, unmethylated G2922
Descriptor: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
Authors:Yelland, J.N, Bravo, J.P.K, Black, J.J.B, Taylor, D.W, Johnson, A.W.
Deposit date:2022-03-24
Release date:2022-12-21
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:A single 2'-O-methylation of ribosomal RNA gates assembly of a functional ribosome.
Nat.Struct.Mol.Biol., 30, 2023
6N8O
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BU of 6n8o by Molmil
Cryo-EM structure of Rpl10-inserted (RI) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8J
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BU of 6n8j by Molmil
Cryo-EM structure of late nuclear (LN) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal protein L11-A, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8L
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BU of 6n8l by Molmil
Cryo-EM structure of early cytoplasmic-late (ECL) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8M
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BU of 6n8m by Molmil
Cryo-EM structure of pre-Lsg1 (PL) pre-60S ribosomal subunit
Descriptor: 5.8S RNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019
6N8N
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BU of 6n8n by Molmil
Cryo-EM structure of Lsg1-engaged (LE) pre-60S ribosomal subunit
Descriptor: 5.8S rRNA, 5S rRNA, 60S ribosomal export protein NMD3, ...
Authors:Zhou, Y, Musalgaonkar, S, Johnson, A.W, Taylor, D.W.
Deposit date:2018-11-29
Release date:2019-03-13
Last modified:2020-01-08
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Tightly-orchestrated rearrangements govern catalytic center assembly of the ribosome.
Nat Commun, 10, 2019

 

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