Author results

1DMW
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CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN
Descriptor:PHENYLALANINE HYDROXYLASE, FE (III) ION, 7,8-DIHYDROBIOPTERIN
Authors:Erlandsen, H., Stevens, R.C., Flatmark, T.
Deposit date:1999-12-15
Release date:2000-03-24
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure and site-specific mutagenesis of pterin-bound human phenylalanine hydroxylase.
Biochemistry, 39, 2000
1LTU
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM, APO (NO IRON BOUND) STRUCTURE
Descriptor:PHENYLALANINE-4-HYDROXYLASE
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.74 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTV
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE WITH BOUND OXIDIZED FE(III)
Descriptor:PHENYLALANINE-4-HYDROXYLASE, FE (III) ION
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-20
Release date:2002-07-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1LTZ
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CRYSTAL STRUCTURE OF CHROMOBACTERIUM VIOLACEUM PHENYLALANINE HYDROXYLASE, STRUCTURE HAS BOUND IRON (III) AND OXIDIZED COFACTOR 7,8-DIHYDROBIOPTERIN
Descriptor:PHENYLALANINE-4-HYDROXYLASE, FE (III) ION, CHLORIDE ION, ...
Authors:Erlandsen, H., Kim, J.Y., Patch, M.G., Han, A., Volner, A., Abu-Omar, M.M., Stevens, R.C.
Deposit date:2002-05-21
Release date:2002-07-17
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates.
J.Mol.Biol., 320, 2002
1TDW
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CRYSTAL STRUCTURE OF DOUBLE TRUNCATED HUMAN PHENYLALANINE HYDROXYLASE BH4-RESPONSIVE PKU MUTANT A313T.
Descriptor:Phenylalanine-4-hydroxylase, FE (III) ION
Authors:Erlandsen, H., Pey, A.L., Gamez, A., Perez, B., Desviat, L.R., Aguado, C., Koch, R., Surendran, S., Tyring, S., Matalon, R., Scriver, C.R., Ugarte, M., Martinez, A., Stevens, R.C.
Deposit date:2004-05-24
Release date:2004-11-30
Last modified:2017-10-11
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
1TG2
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CRYSTAL STRUCTURE OF PHENYLALANINE HYDROXYLASE A313T MUTANT WITH 7,8-DIHYDROBIOPTERIN BOUND
Descriptor:Phenylalanine-4-hydroxylase, FE (III) ION, 2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-7,8-DIHYDRO-6H-PTERIDIN-4-ONE
Authors:Erlandsen, H., Pey, A.L., Gamez, A., Perez, B., Desviat, L.R., Aguado, C., Koch, R., Surendran, S., Tyring, S., Matalon, R., Scriver, C.R., Ugarte, M., Martinez, A., Stevens, R.C.
Deposit date:2004-05-28
Release date:2004-11-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Correction of kinetic and stability defects by tetrahydrobiopterin in phenylketonuria patients with certain phenylalanine hydroxylase mutations.
Proc.Natl.Acad.Sci.Usa, 101, 2004
3PAH
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HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND ADRENALINE INHIBITOR
Descriptor:PHENYLALANINE HYDROXYLASE, FE (III) ION, 4-[(1S)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
Authors:Erlandsen, H., Flatmark, T., Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-03-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
4PAH
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HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND NOR-ADRENALINE INHIBITOR
Descriptor:PHENYLALANINE HYDROXYLASE, FE (III) ION, L-NOREPINEPHRINE
Authors:Erlandsen, H., Flatmark, T., Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2013-02-20
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
5PAH
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HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND DOPAMINE INHIBITOR
Descriptor:PHENYLALANINE 4-MONOOXYGENASE, FE (III) ION, L-DOPAMINE
Authors:Erlandsen, H., Flatmark, T., Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
6PAH
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HUMAN PHENYLALANINE HYDROXYLASE CATALYTIC DOMAIN DIMER WITH BOUND L-DOPA (3,4-DIHYDROXYPHENYLALANINE) INHIBITOR
Descriptor:PHENYLALANINE 4-MONOOXYGENASE, FE (III) ION, 3,4-DIHYDROXYPHENYLALANINE
Authors:Erlandsen, H., Flatmark, T., Stevens, R.C.
Deposit date:1998-08-20
Release date:1999-04-27
Last modified:2011-08-31
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Crystallographic analysis of the human phenylalanine hydroxylase catalytic domain with bound catechol inhibitors at 2.0 A resolution.
Biochemistry, 37, 1998
1PAH
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HUMAN PHENYLALANINE HYDROXYLASE DIMER, RESIDUES 117-424
Descriptor:PHENYLALANINE HYDROXYLASE, FE (III) ION
Authors:Stevens, R.C., Erlandsen, H.
Deposit date:1997-10-25
Release date:1999-01-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:Crystal structure of the catalytic domain of human phenylalanine hydroxylase reveals the structural basis for phenylketonuria.
Nat.Struct.Biol., 4, 1997
2FRX
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CRYSTAL STRUCTURE OF YEBU, A M5C RNA METHYLTRANSFERASE FROM E.COLI
Descriptor:Hypothetical protein yebU
Authors:Erlandsen, H., Nordlund, P., Hallberg, B.M., Johnson, K.A., Ericsson, U.B.
Deposit date:2006-01-20
Release date:2006-08-29
Last modified:2018-05-23
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The structure of the RNA m5C methyltransferase YebU from Escherichia coli reveals a C-terminal RNA-recruiting PUA domain
J.Mol.Biol., 360, 2006
6BFY
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CRYSTAL STRUCTURE OF ENOLASE FROM ESCHERICHIA COLI WITH BOUND 2-PHOSPHOGLYCERATE SUBSTRATE
Descriptor:Enolase, 2-PHOSPHOGLYCERIC ACID, MAGNESIUM ION, ...
Authors:Erlandsen, H., Wright, D., Krucinska, J.
Deposit date:2017-10-27
Release date:2018-10-31
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
6BFZ
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CRYSTAL STRUCTURE OF ENOLASE FROM E. COLI WITH A MIXTURE OF APO FORM, SUBSTRATE, AND PRODUCT FORM
Descriptor:Enolase, MAGNESIUM ION, SULFATE ION, ...
Authors:Erlandsen, H., Wright, D., Krucinska, J.
Deposit date:2017-10-27
Release date:2018-10-31
Last modified:2019-03-20
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Structural and Functional Studies of Bacterial Enolase, a Potential Target against Gram-Negative Pathogens.
Biochemistry, 58, 2019
6D3K
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CRYSTAL STRUCTURE OF UNPHOSPHORYLATED HUMAN PKR KINASE DOMAIN IN COMPLEX WITH ADP
Descriptor:Interferon-induced, double-stranded RNA-activated protein kinase, ADENOSINE-5'-DIPHOSPHATE, ...
Authors:Erlandsen, H., Mayo, C.B., Robinson, V.L., Cole, J.L.
Deposit date:2018-04-16
Release date:2019-07-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural Basis of Protein Kinase R Autophosphorylation.
Biochemistry, 2019
6D3L
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CRYSTAL STRUCTURE OF UNPHOSPHORYLATED HUMAN PKR
Descriptor:Interferon-induced, double-stranded RNA-activated protein kinase
Authors:Erlandsen, H., Mayo, C., Robinson, V.L., Cole, J.L.
Deposit date:2018-04-16
Release date:2019-07-10
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structural Basis of Protein Kinase R Autophosphorylation.
Biochemistry, 2019
3QKW
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STRUCTURE OF STREPTOCOCCUS PARASANGUNINI GTF3 GLYCOSYLTRANSFERASE
Descriptor:Nucleotide sugar synthetase-like protein, URIDINE-5'-DIPHOSPHATE
Authors:Zhu, F., Erlandsen, H., Huang, Y., Ding, L., Zhou, M., Liang, X., Ma, J.-B., Wu, H.
Deposit date:2011-02-01
Release date:2011-06-08
Last modified:2011-08-10
Method:X-RAY DIFFRACTION (2.287 Å)
Cite:Structural and Functional Analysis of a New Subfamily of Glycosyltransferases Required for Glycosylation of Serine-rich Streptococcal Adhesins.
J.Biol.Chem., 286, 2011
3FHD
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CRYSTAL STRUCTURE OF THE SHUTOFF AND EXONUCLEASE PROTEIN FROM KAPOSIS SARCOMA ASSOCIATED HERPESVIRUS
Descriptor:ORF 37, SULFATE ION, MAGNESIUM ION
Authors:Dahlroth, S.L., Gurmu, D., Schmitzberger, F., Haas, J., Erlandsen, H., Nordlund, P.
Deposit date:2008-12-09
Release date:2009-11-24
Last modified:2011-07-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structure of the shutoff and exonuclease protein from the oncogenic Kaposi's sarcoma-associated herpesvirus
Febs J., 276, 2009
1MLW
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CRYSTAL STRUCTURE OF HUMAN TRYPTOPHAN HYDROXYLASE WITH BOUND 7,8-DIHYDRO-L-BIOPTERIN COFACTOR AND FE(III)
Descriptor:Tryptophan 5-monooxygenase, FE (III) ION, 7,8-DIHYDROBIOPTERIN
Authors:Wang, L., Erlandsen, H., Haavik, J., Knappskog, P.M., Stevens, R.C.
Deposit date:2002-08-31
Release date:2002-12-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.71 Å)
Cite:Three-dimensional structure of human tryptophan hydroxylase and its implications for the biosynthesis of the neurotransmitters serotonin and melatonin
Biochemistry, 41, 2002
2PAH
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TETRAMERIC HUMAN PHENYLALANINE HYDROXYLASE
Descriptor:PROTEIN (PHENYLALANINE HYDROXYLASE), FE (III) ION
Authors:Stevens, R.C., Fusetti, F., Erlandsen, H.
Deposit date:1998-05-26
Release date:1999-10-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria.
J.Biol.Chem., 273, 1998
2VEC
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THE CRYSTAL STRUCTURE OF THE PROTEIN YHAK FROM ESCHERICHIA COLI
Descriptor:PIRIN-LIKE PROTEIN YHAK, CHLORIDE ION
Authors:Gurmu, D., Lu, J., Johnson, K.A., Nordlund, P., Holmgren, A., Erlandsen, H.
Deposit date:2007-10-18
Release date:2008-07-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:The Crystal Structure of the Protein Yhak from Escherichia Coli Reveals a New Subclass of Redox Sensitive Enterobacterial Bicupins.
Proteins, 74, 2008
1O3U
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CRYSTAL STRUCTURE OF AN HEPN DOMAIN PROTEIN (TM0613) FROM THERMOTOGA MARITIMA AT 1.75 A RESOLUTION
Descriptor:conserved hypothetical protein TM0613
Authors:Joint Center for Structural Genomics (JCSG)
Deposit date:2003-03-28
Release date:2003-04-22
Last modified:2018-07-18
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of an HEPN domain protein (TM0613) from Thermotoga maritima at 1.75 A resolution.
PROTEINS, 54, 2004
4PFX
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THE HIGHLY CONSERVED DOMAIN OF UNKNOWN FUNCTION 1792 HAS A DISTINCT GLYCOSYLTRANSFERASE FOLD
Descriptor:Putative glycosyltransferase (GalT1), URIDINE-5'-DIPHOSPHATE, ACETATE ION
Authors:Zhang, H., Wu, H.
Deposit date:2014-04-30
Release date:2014-07-23
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.
Nat Commun, 5, 2014
4PHR
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DOMAIN OF UNKNOWN FUNCTION 1792 (DUF1792) WITH MANGANESE
Descriptor:Putative glycosyltransferase (GalT1), URIDINE-5'-DIPHOSPHATE, MANGANESE (II) ION, ...
Authors:Zhang, H., Wu, H.
Deposit date:2014-05-06
Release date:2014-08-06
Last modified:2015-10-14
Method:X-RAY DIFFRACTION (1.34 Å)
Cite:The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.
Nat Commun, 5, 2014
4PHS
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SELENOMETHIONINE SUBSTITUTED STRUCTURE OF DOMAIN OF UNKNOWN FUNCTION 1792 (DUF1792)
Descriptor:Putative glycosyltransferase (GalT1), URIDINE-5'-DIPHOSPHATE
Authors:Zhang, H., Wu, H.
Deposit date:2014-05-06
Release date:2014-08-06
Last modified:2017-09-27
Method:X-RAY DIFFRACTION (1.54 Å)
Cite:The highly conserved domain of unknown function 1792 has a distinct glycosyltransferase fold.
Nat Commun, 5, 2014
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