6NPF

Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.

Summary for 6NPF

• Entry DOI: 10.2210/pdb6npf/pdb
• Related: 6D3Q
• Descriptor: Enolase, L(+)-TARTARIC ACID, SULFATE ION, ... (7 entities in total)
• Functional Keywords: natural inhibitor, complex, enolase, sf2312, lyase
• Biological source: Escherichia coli
• Total number of polymer chains: 6
• Total formula weight: 286848.39

Authors

Erlandsen, H.,Krucinska, J.,Lombardo, M.,Wright, D. (deposition date: 2019-01-17, release date: 2019-11-27, Last modification date: 2023-10-11)

• Primary citation: Krucinska, J.,Lombardo, M.N.,Erlandsen, H.,Hazeen, A.,Duay, S.S.,Pattis, J.G.,Robinson, V.L.,May, E.R.,Wright, D.L.; Functional and structural basis of E. coli enolase inhibition by SF2312: a mimic of the carbanion intermediate.; Sci Rep, 9:17106-17106, 2019; PubMed: 31745118; DOI: 10.1038/s41598-019-53301-3

Experimental method

X-RAY DIFFRACTION (2.57 Å)