6NPF

Structure of E.coli enolase in complex with an analog of the natural product SF-2312 metabolite.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, F...)	Enolase	polymer	449	47373.7	6	UniProt (B7MLA0) Pfam (PF03952) Pfam (PF00113) UniProt (by SIFTS) (P0A6P9)	Escherichia coli	2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase
2	G, L, R (A, B, C)	L(+)-TARTARIC ACID	non-polymer		150.1	3	Chemie (TLA)
3	AA, DA, EA, H, J... (F, A, B, C, D)	SULFATE ION	non-polymer		96.1	11	Chemie (SO4)
4	BA, FA, I, M, Q... (F, E, A, B, C...)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
5	K, N, T, Y (A, B, C, D)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	CA, GA, U (F, E, D)	[(3S)-1-hydroxy-2,5-dioxopyrrolidin-3-yl]phosphonic acid	non-polymer		195.1	3	Chemie (KVM)
7	HA, IA, JA, KA, LA... (A, B, C, D, F...)	water	water		18.0	249	Chemie (HOH)

Sequence modifications

A, B, C, D, F, E: 0 - 431 (UniProt: B7MLA0)

PDB	External Database	Details
Gly -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
Met -14	-	expression tag
Ala -13	-	expression tag
Ser -12	-	expression tag
Met -11	-	expression tag
Thr -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Gln -7	-	expression tag
Gln -6	-	expression tag
Met -5	-	expression tag
Gly -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	284242.0
Non-Polymers*	Number of molecules	27
	Total formula weight	2606.4
All*	Total formula weight	286848.4

*Water molecules are not included.