6D3L

Crystal structure of unphosphorylated human PKR

Summary for 6D3L

Entry DOI	10.2210/pdb6d3l/pdb
Descriptor	Interferon-induced, double-stranded RNA-activated protein kinase (1 entity in total)
Functional Keywords	unphosphorylated, kinase, activation loop swapping, apo, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	37445.77
Authors	Erlandsen, H.,Mayo, C.,Robinson, V.L.,Cole, J.L. (deposition date: 2018-04-16, release date: 2019-07-10, Last modification date: 2023-10-04)
Primary citation	Mayo, C.B.,Erlandsen, H.,Mouser, D.J.,Feinstein, A.G.,Robinson, V.L.,May, E.R.,Cole, J.L. Structural Basis of Protein Kinase R Autophosphorylation. Biochemistry, 58:2967-2977, 2019 Cited by PubMed: 31246429 DOI: 10.1021/acs.biochem.9b00161 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation