6D3K
Crystal structure of unphosphorylated human PKR kinase domain in complex with ADP
Summary for 6D3K
Entry DOI | 10.2210/pdb6d3k/pdb |
Descriptor | Interferon-induced, double-stranded RNA-activated protein kinase, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | unphosphorylated, kinase, complex, activation loop swapping, dimer, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 114744.16 |
Authors | Erlandsen, H.,Mayo, C.B.,Robinson, V.L.,Cole, J.L. (deposition date: 2018-04-16, release date: 2019-07-10, Last modification date: 2023-10-04) |
Primary citation | Mayo, C.B.,Erlandsen, H.,Mouser, D.J.,Feinstein, A.G.,Robinson, V.L.,May, E.R.,Cole, J.L. Structural Basis of Protein Kinase R Autophosphorylation. Biochemistry, 58:2967-2977, 2019 Cited by PubMed: 31246429DOI: 10.1021/acs.biochem.9b00161 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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