6D3K
Crystal structure of unphosphorylated human PKR kinase domain in complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (B, A, C) | Interferon-induced, double-stranded RNA-activated protein kinase | polymer | 323 | 37445.8 | 3 | UniProt (P19525) Pfam (PF00069) | Homo sapiens (Human) | Eukaryotic translation initiation factor 2-alpha kinase 2, eIF-2A protein kinase 2, Interferon-inducible RNA-dependent protein kinase, P1/eIF-2A protein kinase, Protein kinase RNA-activated, Protein kinase R, Tyrosine-protein kinase EIF2AK2, p68 kinase |
| 2 | D, H, N (B, A, C) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 3 | Chemie (ADP) | |||
| 3 | E, I, O, T (B, A, C) | PHOSPHATE ION | non-polymer | 95.0 | 4 | Chemie (PO4) | |||
| 4 | F, J, P (B, A, C) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G, K, L, M, Q... (B, A, C) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | U, V, W (B, A, C) | water | water | 18.0 | 52 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112337.3 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2406.8 | |
| All* | Total formula weight | 114744.2 |
