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1VBX
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN EDTA SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBY
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, AND MN2+ BOUND
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, MANGANESE (II) ION, ...
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VBZ
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN BA2+ SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, BARIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC0
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN IMIDAZOLE AND SR2+ SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, STRONTIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC5
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CRYSTAL STRUCTURE OF THE WILD TYPE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, IN EDTA SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, SODIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
1VC6
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRODUCT WITH C75U MUTAION, CLEAVED IN IMIDAZOLE AND MG2+ SOLUTIONS
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, MAGNESIUM ION
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-04
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
4V42
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CRYSTAL STRUCTURE OF THE RIBOSOME AT 5.5 A RESOLUTION.
Descriptor:30S 16S RIBOSOMAL RNA, TRNA(PHE), A- AND P-SITE MESSENGER RNA CODONS, ...
Authors:Yusupov, M.M., Yusupova, G.Z., Baucom, A., Lieberman, K., Earnest, T.N., Cate, J.H.D., Noller, H.F.
Deposit date:2001-03-30
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (5.5 Å)
Cite:Crystal structure of the ribosome at 5.5 A resolution
Science, 292, 2001
4V49
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CRYSTAL STRUCTURE OF A STREPTOMYCIN DEPENDENT RIBOSOME FROM E. COLI 70S RIBOSOME.
Descriptor:16S RIBOSOMAL RNA, tRNA-Phe, mRNA, ...
Authors:Vila-Sanjurjo, A., Ridgeway, W.K., Seymaner, V., Zhang, W., Santoso, S., Yu, K., Cate, J.H.D.
Deposit date:2003-06-13
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (8.7 Å)
Cite:X-ray Crystal Structures of the WT and a Hyper-Accurate Ribosome From Escherichia Coli
Proc.Natl.Acad.Sci.USA, 100, 2003
4V4A
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CRYSTAL STRUCTURE OF THE WILD TYPE RIBOSOME FROM E. COLI 70S RIBOSOME.
Descriptor:16S RIBOSOMAL RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Vila-Sanjurjo, A., Ridgeway, W.K., Seymaner, V., Zhang, W., Santoso, S., Yu, K., Cate, J.H.D.
Deposit date:2003-06-13
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (9.5 Å)
Cite:X-ray crystal structures of the WT and a hyper-accurate ribosome from Escherichia coli
Proc.Natl.Acad.Sci.USA, 100, 2003
4V4H
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CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOME FROM ESCHERICHIA COLI IN COMPLEX WITH THE ANTIBIOTIC KASUGAMYIN AT 3.5A RESOLUTION.
Descriptor:16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S3, 30S RIBOSOMAL PROTEIN S4, ...
Authors:Schuwirth, B.S., Vila-Sanjurjo, A., Cate, J.H.D.
Deposit date:2006-08-04
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.46 Å)
Cite:Structural analysis of kasugamycin inhibition of translation.
Nat.Struct.Mol.Biol., 13, 2006
4V50
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CRYSTAL STRUCTURE OF RIBOSOME WITH MESSENGER RNA AND THE ANTICODON STEM-LOOP OF P-SITE TRNA.
Descriptor:16S ribosomal RNA, PHE TRNA (UNMODIFIED BASES), MRNA, ...
Authors:Berk, V., Zhang, W., Pai, R.D., Cate, J.H.D.
Deposit date:2006-08-16
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.22 Å)
Cite:Structural basis for mRNA and tRNA positioning on the ribosome.
Proc.Natl.Acad.Sci.Usa, 103, 2006
4V64
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CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOME FROM ESCHERICHIA COLI IN COMPLEX WITH HYGROMYCIN B.
Descriptor:16S ribosomal RNA, 30S ribosomal protein S3, 30S ribosomal protein S4, ...
Authors:Borovinskaya, M.A., Shoji, S., Fredrick, K., Cate, J.H.D.
Deposit date:2008-06-11
Release date:2014-07-09
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis for hygromycin B inhibition of protein biosynthesis
Rna, 14, 2008
6OLE
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX (CDH1-RNC) STALLED BY A DRUG-LIKE MOLECULE WITH AP AND PE TRNAS
Descriptor:18S ribosomal RNA, 40S ribosomal protein SA, 40S ribosomal protein S3a, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLF
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX (CDH1-RNC) STALLED BY A DRUG-LIKE MOLECULE WITH AA AND PE TRNAS
Descriptor:18S ribosomal RNA, 40S ribosomal protein SA, 40S ribosomal protein S3a, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLG
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX STALLED BY A DRUG-LIKE SMALL MOLECULE (CDH1_RNC WITH PP TRNA)
Descriptor:60S ribosomal protein L8, 40S ribosomal protein SA, 60S ribosomal protein L3, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLI
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STRUCTURE OF HUMAN RIBOSOME NASCENT CHAIN COMPLEX SELECTIVELY STALLED BY A DRUG-LIKE SMALL MOLECULE (USO1-RNC)
Descriptor:18S ribosomal RNA, 40S ribosomal protein SA, 40S ribosomal protein S3a, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-16
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OLZ
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX (PCSK9-RNC) STALLED BY A DRUG-LIKE MOLECULE WITH PP TRNA
Descriptor:60S ribosomal protein L8, 40S ribosomal protein SA, 60S ribosomal protein L3, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM0
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX (PCSK9-RNC) STALLED BY A DRUG-LIKE MOLECULE WITH AP AND PE TRNAS
Descriptor:18S ribosomal RNA, 40S ribosomal protein SA, 40S ribosomal protein S3a, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-17
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
6OM7
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HUMAN RIBOSOME NASCENT CHAIN COMPLEX (PCSK9-RNC) STALLED BY A DRUG-LIKE SMALL MOLECULE WITH AA AND PE TRNAS
Descriptor:18S ribosomal RNA, 40S ribosomal protein SA, 40S ribosomal protein S3a, ...
Authors:Li, W., Cate, J.H.D.
Deposit date:2019-04-18
Release date:2019-06-19
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule.
Nat.Struct.Mol.Biol., 26, 2019
4V9C
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ALLOSTERIC CONTROL OF THE RIBOSOME BY SMALL-MOLECULE ANTIBIOTICS
Descriptor:16S ribosomal RNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Cate, J.H.D., Pulk, A., Blanchard, S.C., Wang, L., Feldman, M.B., Wasserman, M.R., Altman, R.
Deposit date:2012-07-25
Release date:2014-07-09
Last modified:2014-12-10
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Allosteric control of the ribosome by small-molecule antibiotics.
Nat.Struct.Mol.Biol., 19, 2012
1JGO
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THE PATH OF MESSENGER RNA THROUGH THE RIBOSOME. THIS FILE, 1JGO, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
Descriptor:30S 16S ribosomal RNA, tRNA(Phe), MESSENGER RNA MK27, ...
Authors:Yusupova, G.Z., Yusupov, M.M., Cate, J.H.D., Noller, H.F.
Deposit date:2001-06-26
Release date:2001-07-20
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (5.6 Å)
Cite:The path of messenger RNA through the ribosome.
Cell(Cambridge,Mass.), 106, 2001
1JGP
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THE PATH OF MESSENGER RNA THROUGH THE RIBOSOME. THIS FILE, 1JGP, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
Descriptor:30S 16S ribosomal RNA, tRNA(Phe), MESSENGER RNA MV36, ...
Authors:Yusupova, G.Z., Yusupov, M.M., Cate, J.H.D., Noller, H.F.
Deposit date:2001-06-26
Release date:2001-07-20
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (7 Å)
Cite:The path of messenger RNA through the ribosome.
Cell(Cambridge,Mass.), 106, 2001
1JGQ
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THE PATH OF MESSENGER RNA THROUGH THE RIBOSOME. THIS FILE, 1JGQ, CONTAINS THE 30S RIBOSOME SUBUNIT, THREE TRNA, AND MRNA MOLECULES. 50S RIBOSOME SUBUNIT IS IN THE FILE 1GIY
Descriptor:30S 16S ribosomal RNA, tRNA(Phe), MESSENGER RNA MF36, ...
Authors:Yusupova, G.Z., Yusupov, M.M., Cate, J.H.D., Noller, H.F.
Deposit date:2001-06-26
Release date:2001-07-20
Last modified:2018-02-14
Method:X-RAY DIFFRACTION (5 Å)
Cite:The path of messenger RNA through the ribosome.
Cell(Cambridge,Mass.), 106, 2001
1SJF
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CRYSTAL STRUCTURE OF THE HEPATITIS DELTA VIRUS GEMONIC RIBOZYME PRECURSOR, WITH C75U MUTAION, IN COBALT HEXAMMINE SOLUTION
Descriptor:Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A, COBALT HEXAMMINE(III)
Authors:Ke, A., Zhou, K., Ding, F., Cate, J.H.D., Doudna, J.A.
Deposit date:2004-03-03
Release date:2004-05-18
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A conformational switch controls hepatitis delta virus ribozyme catalysis.
Nature, 429, 2004
4U1U
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CRYSTAL STRUCTURE OF THE E. COLI RIBOSOME BOUND TO QUINUPRISTIN.
Descriptor:16S rRNA, 30S ribosomal protein S2, 30S ribosomal protein S3, ...
Authors:Noeske, J., Huang, J., Olivier, N.B., Giacobbe, R.A., Zambrowski, M., Cate, J.H.D.
Deposit date:2014-07-16
Release date:2014-07-30
Last modified:2017-11-22
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob.Agents Chemother., 58, 2014
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