3JT1
| Legionella pneumophila glucosyltransferase Lgt1, UDP-bound form | Descriptor: | Putative uncharacterized protein, URIDINE-5'-DIPHOSPHATE | Authors: | Lu, W, Du, J, Belyi, Y, Stahl, M, Zivilikidis, T, Gerhardt, S, Aktories, K, Einsle, O. | Deposit date: | 2009-09-11 | Release date: | 2010-02-02 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural Basis of the Action of Glucosyltransferase Lgt1 from Legionella pneumophila. J.Mol.Biol., 2009
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3JSZ
| Legionella pneumophila glucosyltransferase Lgt1 N293A with UDP-Glc | Descriptor: | MAGNESIUM ION, Putative uncharacterized protein, URIDINE-5'-DIPHOSPHATE-GLUCOSE | Authors: | Lu, W, Du, J, Belyi, Y, Stahl, M, Zivilikidis, T, Gerhardt, S, Aktories, K, Einsle, O. | Deposit date: | 2009-09-11 | Release date: | 2010-02-02 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural Basis of the Action of Glucosyltransferase Lgt1 from Legionella pneumophila. J.Mol.Biol., 2009
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5UP2
| Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, Ro 25-6981, MK-801 and a GluN2B-specific Fab, at pH 6.5 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GluN2B-specific Fab, ... | Authors: | Lu, W, Du, J, Goehring, A, Gouaux, E. | Deposit date: | 2017-02-01 | Release date: | 2017-03-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (6 Å) | Cite: | Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation. Science, 355, 2017
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5UOW
| Triheteromeric NMDA receptor GluN1/GluN2A/GluN2B in complex with glycine, glutamate, MK-801 and a GluN2B-specific Fab, at pH 6.5 | Descriptor: | (5S,10R)-5-methyl-10,11-dihydro-5H-5,10-epiminodibenzo[a,d][7]annulene, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLUTAMIC ACID, ... | Authors: | Lu, W, Du, J, Goehring, A, Gouaux, E. | Deposit date: | 2017-02-01 | Release date: | 2017-03-22 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation. Science, 355, 2017
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6CUD
| Structure of the human TRPC3 in a lipid-occupied, closed state | Descriptor: | (2R)-3-hydroxypropane-1,2-diyl dihexanoate, (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Lu, W, Du, J, Fan, C, Choi, W. | Deposit date: | 2018-03-25 | Release date: | 2018-05-16 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the human lipid-gated cation channel TRPC3. Elife, 7, 2018
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6UIW
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6UIV
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6UIX
| Cryo-EM structure of human CALHM2 gap junction | Descriptor: | Calcium homeostasis modulator protein 2 | Authors: | Lu, W, Du, J, Choi, W. | Deposit date: | 2019-10-01 | Release date: | 2019-11-27 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | The structures and gating mechanism of human calcium homeostasis modulator 2. Nature, 576, 2019
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6WBK
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6WBL
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6WBI
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6WBG
| Cryo-EM structure of human Pannexin 1 channel with its C-terminal tail cleaved by caspase-7 | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Lu, W, Du, J, Ruan, Z. | Deposit date: | 2020-03-26 | Release date: | 2020-06-03 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.97 Å) | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature, 584, 2020
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6WBF
| Cryo-EM structure of wild type human Pannexin 1 channel | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL, ... | Authors: | Lu, W, Du, J, Ruan, Z. | Deposit date: | 2020-03-26 | Release date: | 2020-06-03 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature, 584, 2020
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6WBN
| Cryo-EM structure of human Pannexin 1 channel N255A mutant, gap junction | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, DIACYL GLYCEROL, ... | Authors: | Lu, W, Du, J, Ruan, Z. | Deposit date: | 2020-03-26 | Release date: | 2020-06-03 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature, 584, 2020
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6WBM
| Cryo-EM structure of human Pannexin 1 channel N255A mutant | Descriptor: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, CHOLESTEROL, DIACYL GLYCEROL, ... | Authors: | Lu, W, Du, J, Ruan, Z. | Deposit date: | 2020-03-26 | Release date: | 2020-06-03 | Last modified: | 2021-06-30 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of human pannexin 1 reveal ion pathways and mechanism of gating. Nature, 584, 2020
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7JNC
| cryo-EM structure of human proton-activated chloride channel PAC at pH 4 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel | Authors: | Lu, W, Ruan, R, Du, J. | Deposit date: | 2020-08-04 | Release date: | 2020-11-11 | Last modified: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.73 Å) | Cite: | Structures and pH-sensing mechanism of the proton-activated chloride channel. Nature, 588, 2020
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7JNA
| Cryo-EM structure of human proton-activated chloride channel PAC at pH 8 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Proton-activated chloride channel | Authors: | Lu, W, Ruan, R, Du, J. | Deposit date: | 2020-08-04 | Release date: | 2020-11-11 | Last modified: | 2020-12-23 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures and pH-sensing mechanism of the proton-activated chloride channel. Nature, 588, 2020
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4EYC
| Crystal structure of the cathelin-like domain of human cathelicidin LL-37 (hCLD) | Descriptor: | Cathelicidin antimicrobial peptide | Authors: | Pazgier, M, Pozharski, E, Toth, E, Lu, W. | Deposit date: | 2012-05-01 | Release date: | 2013-02-27 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structural and Functional Analysis of the Pro-Domain of Human Cathelicidin, LL-37. Biochemistry, 52, 2013
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7O0Y
| ABC transporter NosDFY, nucleotide-free in GDN | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O15
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O16
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O14
| ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 1 | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O12
| ABC transporter NosDFY, AMPPNP-bound in GDN | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Probable ABC transporter ATP-binding protein NosF, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O11
| ABC transporter NosDFY, nucleotide-free in GDN, R-domain 1 | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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7O10
| ABC transporter NosDFY, nucleotide-free in GDN, R-domain 2 | Descriptor: | MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... | Authors: | Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. | Deposit date: | 2021-03-28 | Release date: | 2022-04-13 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
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