7JNC

cryo-EM structure of human proton-activated chloride channel PAC at pH 4

Summary for 7JNC

• Entry DOI: 10.2210/pdb7jnc/pdb
• Related: 7JNA
• EMDB information: 22403 22404
• Descriptor: Proton-activated chloride channel, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: pac, pacc1, paorac, asor, tmem206, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 123540.22

Authors

Lu, W.,Ruan, R.,Du, J. (deposition date: 2020-08-04, release date: 2020-11-11, Last modification date: 2020-12-23)

• Primary citation: Ruan, Z.,Osei-Owusu, J.,Du, J.,Qiu, Z.,Lu, W.; Structures and pH-sensing mechanism of the proton-activated chloride channel.; Nature, 588:350-354, 2020; PubMed: 33149300; DOI: 10.1038/s41586-020-2875-7

Experimental method

ELECTRON MICROSCOPY (3.73 Å)