Author results

6CS2
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SARS SPIKE GLYCOPROTEIN - HUMAN ACE2 COMPLEX, STABILIZED VARIANT, ALL ACE2-BOUND PARTICLES
Descriptor:Spike glycoprotein,Fibritin, Angiotensin-converting enzyme 2, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Kirchdoerfer, R.N., Wang, N., Pallesen, J., Turner, H.L., Cottrell, C.A., McLellan, J.S., Ward, A.B.
Deposit date:2018-03-19
Release date:2018-04-11
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis.
Sci Rep, 8, 2018
6DJB
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STRUCTURE OF HUMAN VOLUME REGULATED ANION CHANNEL COMPOSED OF SWELL1 (LRRC8A)
Descriptor:Volume-regulated anion channel subunit LRRC8A
Authors:Kefauver, J.M., Saotome, K., Pallesen, J., Cottrell, C.A., Ward, A.B., Patapoutian, A.
Deposit date:2018-05-24
Release date:2018-08-15
Last modified:2019-11-20
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structure of the human volume regulated anion channel.
Elife, 7, 2018
6PZ8
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MERS S0 TRIMER IN COMPLEX WITH VARIABLE DOMAIN OF ANTIBODY G2
Descriptor:S protein, G2 heavy chain, G2 light chain, ...
Authors:Bowman, C.A., Pallesen, J., Ward, A.B.
Deposit date:2019-07-31
Release date:2019-10-09
Method:ELECTRON MICROSCOPY (4.19 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6FZ4
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STRUCTURE OF GLUK1 LIGAND-BINDING DOMAIN IN COMPLEX WITH N-(7-FLUORO-2,3-DIOXO-6-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINOXALIN-1(2H)-YL)-2-HYDROXYBENZAMIDE AT 1.85 A RESOLUTION
Descriptor:Glutamate receptor ionotropic, kainate 1,Glutamate receptor ionotropic, kainate 1, ...
Authors:Kastrup, J.S., Frydenvang, K., Mollerud, S.
Deposit date:2018-03-14
Release date:2019-01-23
Last modified:2019-03-27
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
Acs Chem Neurosci, 10, 2019
5VZR
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G4 FAB
Descriptor:G4 antibody heavy chain, G4 antibody light chain, GLYCEROL
Authors:Wang, N., Wrapp, D., McLellan, J.S.
Deposit date:2017-05-29
Release date:2017-08-30
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.57 Å)
Cite:Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6CNV
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INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX
Descriptor:Hemagglutinin, Envelope glycoprotein, SD84h, ...
Authors:Luo, J., Obmolova, G.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CNW
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STRUCTURE OF HUMANIZED SINGLE DOMAIN ANTIBODY SD84
Descriptor:humanized antibody SD84h, ACETATE ION, DI(HYDROXYETHYL)ETHER
Authors:Luo, J., Obmolova, O.
Deposit date:2018-03-09
Release date:2018-11-14
Method:X-RAY DIFFRACTION (0.92 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6CK8
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CRYSTAL STRUCTURE OF ANTI-INFLUENZA SINGLE-DOMAIN LLAMA ANTIBODY SD38
Descriptor:Llama antibody SD38, SULFATE ION, PENTAETHYLENE GLYCOL, ...
Authors:Zhu, X., Wilson, I.A.
Deposit date:2018-02-27
Release date:2018-11-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYS
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STRUCTURE OF SINGLE DOMAIN ANTIBODY SD83
Descriptor:Single domain antibody SD83, 1,2-ETHANEDIOL
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYT
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STRUCTURE OF H1 (A/SOLOMON ISLANDS/3/06) INFLUENZA HEMAGGLUTININ IN COMPLEX WITH SD38
Descriptor:Hemagglutinin, Single domain antibody SD38, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYU
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STRUCTURE OF H7(A/SHANGHAI/2/2013) INFLUENZA HEMAGGLUTININ IN COMPLEX SD36
Descriptor:Hemaggluinin HA1, Hemagglutinin, Single domain antibody SD36, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.643 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6FYW
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STRUCTURE OF B/BRISBANE/60/2008 INFLUENZA HEMAGGLUTININ IN COMPLEX WITH SD83
Descriptor:Hemagglutinin, Single domain antibody SD83, N-ACETYL-D-GLUCOSAMINE, ...
Authors:Laursen, N.S., Wilson, I.A.
Deposit date:2018-03-12
Release date:2018-11-07
Last modified:2018-11-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin.
Science, 362, 2018
6SBT
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STRUCTURE OF GLUK1 LIGAND-BINDING DOMAIN (S1S2) IN COMPLEX WITH N-(7-(1H-IMIDAZOL-1-YL)-2,3-DIOXO-6-(TRIFLUOROMETHYL)-3,4-DIHYDROQUINOXALIN-1(2H)-YL BENZAMIDE AT 2.3 A RESOLUTION
Descriptor:Glutamate receptor ionotropic, kainate 1, SULFATE ION, ...
Authors:Moellerud, S., Frydenvang, K., Kastrup, J.S.
Deposit date:2019-07-22
Release date:2019-10-30
Last modified:2019-11-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo Pharmacology.
Acs Chem Neurosci, 10, 2019
6AVN
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CRYSTAL STRUCTURE OF UNBOUND ANTI-HIV ANTIBODY FAB PGV19 AT 2.5 A
Descriptor:PGV19 Fab heavy chain, PGV19 Fab light chain, GLYCEROL, ...
Authors:Sarkar, A., Wilson, I.A.
Deposit date:2017-09-03
Release date:2018-06-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6B0N
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CRYSTAL STRUCTURE OF THE CLEAVAGE-INDEPENDENT PREFUSION HIV ENV GLYCOPROTEIN TRIMER OF THE CLADE A BG505 ISOLATE (NFL CONSTRUCT) IN COMPLEX WITH FABS PGT122 AND PGV19 AT 3.39 A
Descriptor:PGV19 Fab heavy chain, PGV19 light chain, Envelope glycoprotein gp140, ...
Authors:Sarkar, A., Irimia, A., Wilson, I.A.
Deposit date:2017-09-14
Release date:2018-05-30
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
Nat Commun, 9, 2018
6PXG
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CRYSTAL STRUCTURE OF MERS-COV NEUTRALIZING ANTIBODY G2 FAB
Descriptor:G2 Fab Heavy Chain, G2 Fab Light chain
Authors:Wang, N., McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
6PXH
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CRYSTAL STRUCTURE OF MERS-COV S1-NTD BOUND WITH G2 FAB
Descriptor:MERS-CoV S1-NTD, G2 heavy chain, G2 light chain, ...
Authors:Wang, N., McLellan, J.S.
Deposit date:2019-07-26
Release date:2019-09-25
Last modified:2019-10-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural Definition of a Neutralization-Sensitive Epitope on the MERS-CoV S1-NTD.
Cell Rep, 28, 2019
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