Author results

3Q3X
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CRYSTAL STRUCTURE OF THE MAIN PROTEASE (3C) FROM HUMAN ENTEROVIRUS B EV93
Descriptor:HEVB EV93 3C protease, GLYCEROL, MAGNESIUM ION
Authors:Costenaro, L., Sola, M., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2010-12-22
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3Q3Y
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COMPLEX STRUCTURE OF HEVB EV93 MAIN PROTEASE 3C WITH COMPOUND 1 (AG7404)
Descriptor:HEVB EV93 3C protease, ethyl (4R)-4-({(2S)-2-[3-{[(5-methyl-1,2-oxazol-3-yl)carbonyl]amino}-2-oxopyridin-1(2H)-yl]pent-4-ynoyl}amino)-5-[(3S)-2-oxopyrrolidin-3-yl]pentanoate, 1,2-ETHANEDIOL, ...
Authors:Costenaro, L., Kaczmarska, Z., Arnan, C., Sola, M., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2010-12-22
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.32 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
3RUO
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COMPLEX STRUCTURE OF HEVB EV93 MAIN PROTEASE 3C WITH RUPINTRIVIR (AG7088)
Descriptor:HEVB EV93 3C PROTEASE, 4-{2-(4-FLUORO-BENZYL)-6-METHYL-5-[(5-METHYL-ISOXAZOLE-3-CARBONYL)-AMINO]-4-OXO-HEPTANOYLAMINO}-5-(2-OXO-PYRROLIDIN-3-YL)-PENTANOIC ACID ETHYL ESTER, MAGNESIUM ION, ...
Authors:Kaczmarska, Z., Janowski, R., Costenaro, L., Coutard, B., Norder, H., Canard, B., Coll, M.
Deposit date:2011-05-05
Release date:2011-09-07
Last modified:2011-10-05
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Structural Basis for Antiviral Inhibition of the Main Protease, 3C, from Human Enterovirus 93.
J.Virol., 85, 2011
4UD1
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STRUCTURE OF THE N TERMINAL DOMAIN OF THE MERS COV NUCLEOCAPSID
Descriptor:N PROTEIN, AMMONIUM ION, IMIDAZOLE, ...
Authors:Papageorgiou, N., Lichiere, J., Ferron, F., Canard, B., Coutard, B.
Deposit date:2014-12-05
Release date:2015-12-02
Last modified:2016-03-02
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structural Characterization of the N-Terminal Part of the Mers-Cov Nucleocapsid by X-Ray Diffraction and Small-Angle X-Ray Scattering
Acta Crystallogr.,Sect.D, 72, 2016
5FVA
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TOSCANA VIRUS NUCLEOCAPSID PROTEIN
Descriptor:NUCLEOPROTEIN, SODIUM ION
Authors:Baklouti, A., Sevajol, M., Goulet, A., Lichiere, J., Ferron, F., Canard, B., Charrel, R.N., Coutard, B., Papageorgiou, N.
Deposit date:2016-02-03
Release date:2016-03-09
Last modified:2017-08-23
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Toscana virus nucleoprotein oligomer organization observed in solution.
Acta Crystallogr D Struct Biol, 73, 2017
6G13
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C-TERMINAL DOMAIN OF MERS-COV NUCLEOCAPSID
Descriptor:Nucleoprotein, trimethylamine oxide, DI(HYDROXYETHYL)ETHER, ...
Authors:Nguyen, T.H.V., Ferron, F.P., Lichiere, J., Canard, B., Papageorgiou, N., Coutard, B.
Deposit date:2018-03-20
Release date:2019-02-27
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Structure and oligomerization state of the C-terminal region of the Middle East respiratory syndrome coronavirus nucleoprotein.
Acta Crystallogr D Struct Biol, 75, 2019
1OKS
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CRYSTAL STRUCTURE OF THE MEASLES VIRUS PHOSPHOPROTEIN XD DOMAIN
Descriptor:RNA POLYMERASE ALPHA SUBUNIT, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID
Authors:Johansson, K., Bourhis, J.-M., Campanacci, V., Cambillau, C., Canard, B., Longhi, S.
Deposit date:2003-07-29
Release date:2003-09-01
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of the Measles Virus Phosphoprotein Domain Responsible for the Induced Folding of the C-Terminal Domain of the Nucleoprotein
J.Biol.Chem., 278, 2003
2J7U
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN
Descriptor:RNA DEPENDENT RNA POLYMERASE, ZINC ION, MAGNESIUM ION, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
2J7W
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DENGUE VIRUS NS5 RNA DEPENDENT RNA POLYMERASE DOMAIN COMPLEXED WITH 3' DGTP
Descriptor:POLYPROTEIN, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Yap, T.L., Xu, T., Chen, Y.L., Malet, H., Egloff, M.P., Canard, B., Vasudevan, S.G., Lescar, J.
Deposit date:2006-10-17
Release date:2007-03-13
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal Structure of the Dengue Virus RNA- Dependent RNA Polymerase Catalytic Domain at 1.85 Angstrom Resolution.
J.Virol., 81, 2007
4C6A
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HIGH RESOLUTION STRUCTURE OF THE NUCLEOSIDE DIPHOSPHATE KINASE
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, DI(HYDROXYETHYL)ETHER
Authors:Priet, S., Ferron, F., Alvarez, K., Verron, M., Canard, B.
Deposit date:2013-09-18
Release date:2013-11-20
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (1.25 Å)
Cite:Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
4CP5
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NDPK IN COMPLEX WITH (RP)-SPMPAPP
Descriptor:NUCLEOSIDE DIPHOSPHATE KINASE, CYTOSOLIC, [[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-sulfanyl-phosphoryl] phosphono hydrogen phosphate
Authors:Priet, S., Ferron, F., Alvarez, K., Verron, M., Canard, B.
Deposit date:2014-01-31
Release date:2015-02-11
Last modified:2015-04-22
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Enzymatic Synthesis of Acyclic Nucleoside Thiophosphonate Diphosphates: Effect of the Alpha-Phosphorus Configuration on HIV-1 RT Activity.
Antiviral Res., 117, 2015
4UCI
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, S-ADENOSYLMETHIONINE, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-10-14
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCJ
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.26 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCK
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, S-ADENOSYLMETHIONINE
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCL
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-03
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCY
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, SULFATE ION
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.83 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UCZ
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, ZINC ION, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
4UD0
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X-RAY STRUCTURE AND ACTIVITIES OF AN ESSENTIAL MONONEGAVIRALES L- PROTEIN DOMAIN
Descriptor:RNA-DIRECTED RNA POLYMERASE L, SULFATE ION, ZINC ION, ...
Authors:Paesen, G.C., Collet, A., Sallamand, C., Debart, F., Vasseur, J.J., Canard, B., Decroly, E., Grimes, J.M.
Deposit date:2014-12-05
Release date:2015-11-18
Last modified:2019-04-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:X-Ray Structure and Activities of an Essential Mononegavirales L-Protein Domain.
Nat.Commun., 6, 2015
5LRP
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MOPEIA VIRUS EXONUCLEASE DOMAIN COMPLEXED WITH MAGNESIUM
Descriptor:Nucleoprotein, ZINC ION, MAGNESIUM ION
Authors:Yekwa, E.L., Khourieh, J., Canard, B., Ferron, F.
Deposit date:2016-08-19
Release date:2017-07-05
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.941 Å)
Cite:Activity inhibition and crystal polymorphism induced by active-site metal swapping.
Acta Crystallogr D Struct Biol, 73, 2017
5LS4
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MOPEIA VIRUS EXONUCLEASE DOMAIN COMPLEXED WITH CALCIUM
Descriptor:Nucleoprotein, CALCIUM ION, ZINC ION, ...
Authors:Yekwa, E.L., Canard, B., Ferron, F.
Deposit date:2016-08-22
Release date:2017-07-05
Last modified:2017-08-30
Method:X-RAY DIFFRACTION (1.469 Å)
Cite:Activity inhibition and crystal polymorphism induced by active-site metal swapping.
Acta Crystallogr D Struct Biol, 73, 2017
5LTF
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE COMPLEXED WITH CATALYTIC IONS
Descriptor:RNA-directed RNA polymerase L, MAGNESIUM ION
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Ferron, F.
Deposit date:2016-09-06
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.43 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5LTN
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE COMPLEXED WITH DPBA
Descriptor:RNA-directed RNA polymerase L, MAGNESIUM ION, GLYCEROL, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-09-07
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5LTS
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE MUTANT D118A
Descriptor:RNA-directed RNA polymerase L, CHLORIDE ION, SODIUM ION, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-09-07
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (2.51 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018
5NFY
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SARS-COV NSP10/NSP14 DYNAMIC COMPLEX
Descriptor:Polyprotein 1ab, ZINC ION, DI(HYDROXYETHYL)ETHER
Authors:Ferron, F., Gluais, L., Vonrhein, C., Bricogne, G., Canard, B., Imbert, I.
Deposit date:2017-03-16
Release date:2018-01-10
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.382 Å)
Cite:Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5T2T
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CRYSTAL STRUCTURE OF LYMPHOCYTIC CHORIOMENINGITIS MAMMARENAVIRUS ENDONUCLEASE BOUND TO COMPOUND L742001
Descriptor:RNA-directed RNA polymerase L, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, ...
Authors:Saez-Ayala, M., Yekwa, E.L., Canard, B., Alvarez, K., Ferron, F.
Deposit date:2016-08-24
Release date:2017-09-13
Last modified:2018-05-30
Method:X-RAY DIFFRACTION (1.967 Å)
Cite:Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.
IUCrJ, 5, 2018