5T2T

Crystal structure of Lymphocytic choriomeningitis mammarenavirus endonuclease bound to compound L742001

Summary for 5T2T

• Entry DOI: 10.2210/pdb5t2t/pdb
• Descriptor: RNA-directed RNA polymerase L, MANGANESE (II) ION, (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, ... (7 entities in total)
• Functional Keywords: mammarenavirus, lcmv, endonuclease, inhibitor, transferase
• Biological source: Lymphocytic choriomeningitis mammarenavirus
• Cellular location: Virion : A0A059U382
• Total number of polymer chains: 2
• Total formula weight: 48269.19

Authors

Saez-Ayala, M.,Yekwa, E.L.,Canard, B.,Alvarez, K.,Ferron, F. (deposition date: 2016-08-24, release date: 2017-09-13, Last modification date: 2024-01-17)

• Primary citation: Saez-Ayala, M.,Yekwa, E.L.,Carcelli, M.,Canard, B.,Alvarez, K.,Ferron, F.; Crystal structures ofLymphocytic choriomeningitis virusendonuclease domain complexed with diketo-acid ligands.; IUCrJ, 5:223-235, 2018; PubMed: 29765612; DOI: 10.1107/S2052252518001021

Experimental method

X-RAY DIFFRACTION (1.967 Å)